DE69212135D1 - Herstellung von homogenen Hydrogel-Copolymeren - Google Patents

Herstellung von homogenen Hydrogel-Copolymeren

Info

Publication number
DE69212135D1
DE69212135D1 DE69212135T DE69212135T DE69212135D1 DE 69212135 D1 DE69212135 D1 DE 69212135D1 DE 69212135 T DE69212135 T DE 69212135T DE 69212135 T DE69212135 T DE 69212135T DE 69212135 D1 DE69212135 D1 DE 69212135D1
Authority
DE
Germany
Prior art keywords
ewc
monomer
homopolymer
hydrogel
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69212135T
Other languages
English (en)
Other versions
DE69212135T2 (de
Inventor
Peter Kuzma
Daniel Moro
Harry Quandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indevus Pharmaceuticals Inc
Original Assignee
Valera Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valera Pharmaceuticals Inc filed Critical Valera Pharmaceuticals Inc
Publication of DE69212135D1 publication Critical patent/DE69212135D1/de
Application granted granted Critical
Publication of DE69212135T2 publication Critical patent/DE69212135T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C41/04—Rotational or centrifugal casting, i.e. coating the inside of a mould by rotating the mould
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Nanotechnology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)
DE69212135T 1992-01-14 1992-01-16 Herstellung von homogenen Hydrogel-Copolymeren Expired - Lifetime DE69212135T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU10182/92A AU652984B2 (en) 1992-01-14 1992-01-14 Preparation of homogeneous hydrogel copolymers
CA002059406A CA2059406C (en) 1992-01-14 1992-01-15 Preparation of homogeneous hydrogel copolymers
EP92300395A EP0551699B1 (de) 1992-01-14 1992-01-16 Herstellung von homogenen Hydrogel-Copolymeren
JP02024792A JP3227462B2 (ja) 1992-01-14 1992-02-05 均一ヒドロゲルコポリマーの製法

Publications (2)

Publication Number Publication Date
DE69212135D1 true DE69212135D1 (de) 1996-08-14
DE69212135T2 DE69212135T2 (de) 1997-01-30

Family

ID=27422424

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69212135T Expired - Lifetime DE69212135T2 (de) 1992-01-14 1992-01-16 Herstellung von homogenen Hydrogel-Copolymeren

Country Status (6)

Country Link
EP (1) EP0551699B1 (de)
JP (1) JP3227462B2 (de)
AT (1) ATE140243T1 (de)
AU (1) AU652984B2 (de)
CA (1) CA2059406C (de)
DE (1) DE69212135T2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1177627C (zh) * 1997-06-20 2004-12-01 阿克佐诺贝尔公司 预装填的置入装置
US6645192B2 (en) * 1998-09-30 2003-11-11 Ivy Animal Health, Inc. Pellet implant system for immediate and delayed release of antiparasitic drug
JP3917052B2 (ja) 2002-10-16 2007-05-23 信和化工株式会社 コポリマー、これを用いた吸着剤又は濃縮媒体、固相マイクロ抽出用注射針
WO2006099288A2 (en) * 2005-03-11 2006-09-21 Indevus Pharmaceuticals, Inc. Controlled release formulations of octreotide
US7759312B2 (en) 2005-03-11 2010-07-20 Endo Pharmaceuticals Solutions Inc. Delivery of dry formulations of octreotide
AU2008245710B2 (en) 2007-04-27 2013-10-17 Endo Pharmaceuticals Solutions Inc. Implant device release agents and methods of using same
EP2303226B1 (de) 2008-06-25 2016-03-23 Endo Pharmaceuticals Solutions Inc. Verlängerte freisetzung von exenatid und anderen polypeptiden
CA2729139C (en) 2008-06-25 2016-07-26 Endo Pharmaceuticals Solutions Inc. Octreotide implant having a release agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2168331A (en) * 1936-10-17 1939-08-08 Du Pont Cast resin with integral sheen
GB1306541A (en) * 1969-01-20 1973-02-14 Ceskoslovenska Akademie Ved Method of manufacturing tubes by centrifugal casting
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
WO1990009168A1 (en) * 1989-02-16 1990-08-23 National Research Development Corporation Dispensing device

Also Published As

Publication number Publication date
AU652984B2 (en) 1994-09-15
JPH05269760A (ja) 1993-10-19
JP3227462B2 (ja) 2001-11-12
DE69212135T2 (de) 1997-01-30
AU1018292A (en) 1993-07-29
CA2059406C (en) 1996-05-28
EP0551699B1 (de) 1996-07-10
ATE140243T1 (de) 1996-07-15
CA2059406A1 (en) 1993-07-16
EP0551699A1 (de) 1993-07-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: PATENTANWAELTE RUFF, WILHELM, BEIER, DAUSTER & PARTNER, 70173 STUTTGART

8327 Change in the person/name/address of the patent owner

Owner name: HYDRO MED SCIENCES, INC., WILMINGTON, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: INDEVUS PHARMACEUTICALS, INC., LEXINGTON, MASS, US