DE69206765D1 - Verfahren zur herstellung von 2',3'-dideoxy-beta-nucleosiden - Google Patents

Verfahren zur herstellung von 2',3'-dideoxy-beta-nucleosiden

Info

Publication number
DE69206765D1
DE69206765D1 DE69206765T DE69206765T DE69206765D1 DE 69206765 D1 DE69206765 D1 DE 69206765D1 DE 69206765 T DE69206765 T DE 69206765T DE 69206765 T DE69206765 T DE 69206765T DE 69206765 D1 DE69206765 D1 DE 69206765D1
Authority
DE
Germany
Prior art keywords
dideoxy
producing
nucleosides
beta
beta nucleosides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69206765T
Other languages
English (en)
Other versions
DE69206765T2 (de
Inventor
Hiroshi Kawakami
Katsuya Matsumoto
Koshi Koseki
Takashi Ebata
Hajime Matsushita
Kazuo Itoh
Yoshitake Naoi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tobacco Inc
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of DE69206765D1 publication Critical patent/DE69206765D1/de
Application granted granted Critical
Publication of DE69206765T2 publication Critical patent/DE69206765T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69206765T 1991-06-14 1992-06-12 Verfahren zur herstellung von 2',3'-dideoxy-beta-nucleosiden Expired - Fee Related DE69206765T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3143446A JPH04368382A (ja) 1991-06-14 1991-06-14 ２′，３′−ジデオキシ−β−ヌクレオシドの製造方法
PCT/JP1992/000752 WO1992022548A1 (en) 1991-06-14 1992-06-12 PROCESS FOR PRODUCING 2',3'-DIDEOXY-β-NUCLEOSIDE

Publications (2)

Publication Number Publication Date
DE69206765D1 true DE69206765D1 (de) 1996-01-25
DE69206765T2 DE69206765T2 (de) 1996-09-05

Family

ID=15338890

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69206765T Expired - Fee Related DE69206765T2 (de) 1991-06-14 1992-06-12 Verfahren zur herstellung von 2',3'-dideoxy-beta-nucleosiden

Country Status (5)

Country Link
US (1) US5416204A (de)
EP (1) EP0544010B1 (de)
JP (1) JPH04368382A (de)
DE (1) DE69206765T2 (de)
WO (1) WO1992022548A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002255707A1 (en) 2001-03-15 2002-10-03 Trustees Of Boston College, The Selective anti-viral nucleoside chain terminators
JP4603274B2 (ja) * 2004-02-24 2010-12-22 三井化学株式会社 ２’−デオキシ−５−トリフルオロメチルウリジンの製造方法
AT502635A1 (de) * 2005-11-09 2007-05-15 Saischek Und Partner Meg Neue 1,3-dithioverbindungen, verfahren zu deren herstellung und ihre verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640267B2 (fr) * 1988-01-19 1992-02-14 Univ Paris Curie Procede de synthese de l'azido-3(prime)-desoxy-3(prime)-thymidine et analogues
US4921950A (en) * 1988-06-09 1990-05-01 Burroughs Wellcome Co. Preparation of 3'azido-3-'-deoxythymidine
US4987224A (en) * 1988-08-02 1991-01-22 University Of Georgia Research Foundation, Inc. Method of preparation of 2',3'-dideoxynucleosides
JPH03215484A (ja) * 1990-01-16 1991-09-20 Japan Tobacco Inc ２’，３’―ジデオキシ―β―リボヌクレオシドの製造方法
JPH0454193A (ja) * 1990-05-25 1992-02-21 Japan Tobacco Inc ２’，３’―ジデオキシ―２’，３’―ジデヒドロ―β―リボヌクレオシドの製造方法
US5220003A (en) * 1991-03-29 1993-06-15 The Regents Of The University Of California Process for the synthesis of 2',3'-dideoxynucleosides

Also Published As

Publication number Publication date
US5416204A (en) 1995-05-16
EP0544010A4 (en) 1993-07-14
EP0544010A1 (de) 1993-06-02
DE69206765T2 (de) 1996-09-05
WO1992022548A1 (en) 1992-12-23
EP0544010B1 (de) 1995-12-13
JPH04368382A (ja) 1992-12-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee