DE691581C - Process for the production of long-lasting solutions of mustard - Google Patents

Process for the production of long-lasting solutions of mustard

Info

Publication number
DE691581C
DE691581C DE1938M0140969 DEM0140969D DE691581C DE 691581 C DE691581 C DE 691581C DE 1938M0140969 DE1938M0140969 DE 1938M0140969 DE M0140969 D DEM0140969 D DE M0140969D DE 691581 C DE691581 C DE 691581C
Authority
DE
Germany
Prior art keywords
mustard
production
long
mustard oil
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1938M0140969
Other languages
German (de)
Inventor
Dr Phil Alfred Kuhn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL52445D priority Critical patent/NL52445C/xx
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Priority to DE1938M0140969 priority patent/DE691581C/en
Application granted granted Critical
Publication of DE691581C publication Critical patent/DE691581C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)

Description

Verfahren zur Herstellung haltbarer Lösungen von Senföl Die Erfindung betrifft ein Verfahren zur Herstellung haltbarer Lösungen von Senföl.Method of Making Stable Solutions of Mustard Oil The invention relates to a process for making durable solutions of mustard oil.

Das Verfahren besteht darin, daß Senföl in Gegenwart von Ameisensäure und Åthylacetat als Lösungsvermittler in Benzin oder Tetrachlorkohlenstoff gelöst wird. Diese Lösung stellt ein besonders gutes Hautreizinittel dar.The method consists in making mustard oil in the presence of formic acid and ethyl acetate as a solubilizer dissolved in gasoline or carbon tetrachloride will. This solution is a particularly good skin irritant.

Es ist bekannt, daß Senföl in verdünnter Lösung, z.B. 2%iger Lösung, ein ausgezeichnetes Hautreizmittel darstellt, ebenso bekannt ist es, daß das Öl sich in Benzin löst. Nach dem Deutschen Arzneibuch wird als Verdünnungsmittel Weingeist verwendet. Diese Zubereitung hat bekanntlich den großen Nachteil, daß sie in kurzer Zeit durch Umsetzung des Senföles wirkungslos wird. It is known that mustard oil in a dilute solution, e.g. 2% solution, is an excellent skin irritant, just as it is known that the oil dissolves in gasoline. According to the German Pharmacopoeia, alcohol is used as a diluent used. This preparation is known to have the major disadvantage that it is in short Time becomes ineffective through conversion of the mustard oil.

Nach der neuen Erfindung werden diese Schwierigkeiten vermieden, wenn man Senföl (in der Technik werden hierfür 2 Obige Lösungen venvendet) in Gegenwart von Ameisensäure und Äthylacetat als Lösungsvermittler in Benzin oder Tetrachlorkohlenstoff löst. According to the new invention, these difficulties are avoided, if you have mustard oil (in the technology 2 above solutions are used for this) in the presence of formic acid and ethyl acetate as solubilizers in gasoline or carbon tetrachloride solves.

Diese Zubereitungen sind, wenn sie vor Licht geschützt sind, über Jahre haltbar. Als Lichtschutz genügt die in der Pharmazie übliche braune Flasche. Die Zubereitung mit Tetrachlorkohlenstoff hat den besonderen Vorteil, daß sie nicht brennbar ist. These preparations are over when protected from light Durable for years. The brown bottle commonly used in pharmacy is sufficient as light protection. The preparation with carbon tetrachloride has the particular advantage that it does not is flammable.

Durch die Gegenwart von Anie-is ens äure, die sich weder in Benzin noch in Tetrachlorkohlenstoff löst, wird die Wirkung des Senföls als Hautreizmittel gesteigert. DurchÄthylacetat als Lösungsvermittler gelingt es, die gewünschte Menge Ameisensäure in dem Benzin bzw. dem Tetrachlorkohlenstoff in Lösung zu bringen. By the presence of anie-isic acid, which is neither in gasoline Still dissolving in carbon tetrachloride, mustard oil acts as a skin irritant increased. By using ethyl acetate as a solubilizer, it is possible to obtain the desired amount To bring formic acid in the gasoline or the carbon tetrachloride in solution.

Ausf ührungsb eis,pliel Zu 6,8 kg Tetrachlorkohlenstoff werden ?..2 kg Senföl zugesetzt; dann werden 2,5 kg Äthylacetat zugefügt und zuletzt o, 5 kg Ameisensäure. Execution rules, pliel To become 6.8 kg of carbon tetrachloride? .. 2 kg of mustard oil added; then 2.5 kg of ethyl acetate are added and finally 0.5 kg Formic acid.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung haltbarer Lösungen von Senföl, dadurch gekennzeichnet, daß Senföl in Gegenwart von Ameisensäure und Äthylacetat als Lösungsvermittler in Benzin oder Tetrachlorkohlenstoff gelöst wird. PATENT CLAIM: Process for the production of durable solutions of Mustard oil, characterized in that mustard oil in the presence of formic acid and ethyl acetate is dissolved as a solubilizer in gasoline or carbon tetrachloride.
DE1938M0140969 1938-03-10 1938-03-10 Process for the production of long-lasting solutions of mustard Expired DE691581C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NL52445D NL52445C (en) 1938-03-10
DE1938M0140969 DE691581C (en) 1938-03-10 1938-03-10 Process for the production of long-lasting solutions of mustard

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1938M0140969 DE691581C (en) 1938-03-10 1938-03-10 Process for the production of long-lasting solutions of mustard

Publications (1)

Publication Number Publication Date
DE691581C true DE691581C (en) 1940-05-31

Family

ID=7334698

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1938M0140969 Expired DE691581C (en) 1938-03-10 1938-03-10 Process for the production of long-lasting solutions of mustard

Country Status (2)

Country Link
DE (1) DE691581C (en)
NL (1) NL52445C (en)

Also Published As

Publication number Publication date
NL52445C (en)

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