DE69131401T2 - Tc(III)-99m MITTEL ZUR MYOKARDIALEN DARSTELLUNG UND VERFAHREN ZUR VERWENDUNG - Google Patents

Tc(III)-99m MITTEL ZUR MYOKARDIALEN DARSTELLUNG UND VERFAHREN ZUR VERWENDUNG

Info

Publication number
DE69131401T2
DE69131401T2 DE69131401T DE69131401T DE69131401T2 DE 69131401 T2 DE69131401 T2 DE 69131401T2 DE 69131401 T DE69131401 T DE 69131401T DE 69131401 T DE69131401 T DE 69131401T DE 69131401 T2 DE69131401 T2 DE 69131401T2
Authority
DE
Germany
Prior art keywords
myocardial
agent
clearance
iii
humans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131401T
Other languages
English (en)
Other versions
DE69131401D1 (de
Inventor
Steven Woulfe
Edward Deutsch
Mary Dyszlewski
William Neumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/632,285 external-priority patent/US5112595A/en
Priority claimed from US07/680,446 external-priority patent/US5112594A/en
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of DE69131401D1 publication Critical patent/DE69131401D1/de
Application granted granted Critical
Publication of DE69131401T2 publication Critical patent/DE69131401T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
  • Coloring (AREA)
  • Pyrane Compounds (AREA)
  • Guiding Agricultural Machines (AREA)
DE69131401T 1990-12-21 1991-12-20 Tc(III)-99m MITTEL ZUR MYOKARDIALEN DARSTELLUNG UND VERFAHREN ZUR VERWENDUNG Expired - Fee Related DE69131401T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/632,285 US5112595A (en) 1990-12-21 1990-12-21 99MTC(III) myocardial imaging agents and method of use
US07/680,446 US5112594A (en) 1991-04-04 1991-04-04 Kit for preparing a technetium-99m myocardial imaging agent
PCT/US1991/009617 WO1992011040A2 (en) 1990-12-21 1991-12-20 99mTc(III) MYOCARDIAL IMAGING AGENTS AND METHOD OF USE

Publications (2)

Publication Number Publication Date
DE69131401D1 DE69131401D1 (de) 1999-08-05
DE69131401T2 true DE69131401T2 (de) 1999-12-23

Family

ID=27091590

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131401T Expired - Fee Related DE69131401T2 (de) 1990-12-21 1991-12-20 Tc(III)-99m MITTEL ZUR MYOKARDIALEN DARSTELLUNG UND VERFAHREN ZUR VERWENDUNG

Country Status (7)

Country Link
EP (1) EP0563328B1 (de)
JP (1) JPH06504063A (de)
AT (1) ATE181673T1 (de)
AU (1) AU665181B2 (de)
CA (1) CA2097081A1 (de)
DE (1) DE69131401T2 (de)
WO (1) WO1992011040A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489054A (en) * 1980-04-18 1984-12-18 Research Corporation Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4795626A (en) * 1985-05-10 1989-01-03 University Of Cincinnati 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo

Also Published As

Publication number Publication date
DE69131401D1 (de) 1999-08-05
WO1992011040A3 (en) 1992-10-15
AU665181B2 (en) 1995-12-21
JPH06504063A (ja) 1994-05-12
WO1992011040A2 (en) 1992-07-09
EP0563328A1 (de) 1993-10-06
AU1151492A (en) 1992-07-22
CA2097081A1 (en) 1992-06-22
EP0563328B1 (de) 1999-06-30
ATE181673T1 (de) 1999-07-15

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee