DE69128479D1 - Glukagon-analoge mit austauschungen oder deletionen in asp-9 - Google Patents

Glukagon-analoge mit austauschungen oder deletionen in asp-9

Info

Publication number
DE69128479D1
DE69128479D1 DE69128479T DE69128479T DE69128479D1 DE 69128479 D1 DE69128479 D1 DE 69128479D1 DE 69128479 T DE69128479 T DE 69128479T DE 69128479 T DE69128479 T DE 69128479T DE 69128479 D1 DE69128479 D1 DE 69128479D1
Authority
DE
Germany
Prior art keywords
glucagon analogs
deletions
asp
exchanges
acid residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69128479T
Other languages
English (en)
Other versions
DE69128479T2 (de
Inventor
Robert Merrifield
Cecilia Unson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Publication of DE69128479D1 publication Critical patent/DE69128479D1/de
Application granted granted Critical
Publication of DE69128479T2 publication Critical patent/DE69128479T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69128479T 1990-08-31 1991-08-08 Glukagon-analoge mit austauschungen oder deletionen in asp-9 Expired - Fee Related DE69128479T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57597090A 1990-08-31 1990-08-31
PCT/US1991/005643 WO1992004042A1 (en) 1990-08-31 1991-08-08 Glucagon analogs with asp9 replacements or deletions

Publications (2)

Publication Number Publication Date
DE69128479D1 true DE69128479D1 (de) 1998-01-29
DE69128479T2 DE69128479T2 (de) 1998-06-04

Family

ID=24302433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69128479T Expired - Fee Related DE69128479T2 (de) 1990-08-31 1991-08-08 Glukagon-analoge mit austauschungen oder deletionen in asp-9

Country Status (5)

Country Link
EP (1) EP0546013B1 (de)
AT (1) ATE161184T1 (de)
AU (1) AU8497391A (de)
DE (1) DE69128479T2 (de)
WO (1) WO1992004042A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480867A (en) * 1993-12-29 1996-01-02 The Rockefeller University Glucagon analogs with serine replacements
WO2013004983A1 (en) 2011-07-04 2013-01-10 Imperial Innovations Limited Novel compounds and their effects on feeding behaviour

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879273A (en) * 1987-05-22 1989-11-07 The Rockefeller University Glucagon homologs and therapeutic use thereof
DK0567562T3 (da) * 1991-01-17 1996-07-29 Zymogenetics Inc Fremgangsmåde til påvisning af glucagonantagonister

Also Published As

Publication number Publication date
EP0546013B1 (de) 1997-12-17
WO1992004042A1 (en) 1992-03-19
ATE161184T1 (de) 1998-01-15
DE69128479T2 (de) 1998-06-04
AU8497391A (en) 1992-03-30
EP0546013A4 (en) 1993-09-15
EP0546013A1 (de) 1993-06-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee