DE69127846D1 - Stereoselektives Verfahren zur Herstellung von 2-Amino-Ethanol-Derivaten mit zentralanalgetischer Aktivität und Zwischenprodukten - Google Patents

Stereoselektives Verfahren zur Herstellung von 2-Amino-Ethanol-Derivaten mit zentralanalgetischer Aktivität und Zwischenprodukten

Info

Publication number
DE69127846D1
DE69127846D1 DE69127846T DE69127846T DE69127846D1 DE 69127846 D1 DE69127846 D1 DE 69127846D1 DE 69127846 T DE69127846 T DE 69127846T DE 69127846 T DE69127846 T DE 69127846T DE 69127846 D1 DE69127846 D1 DE 69127846D1
Authority
DE
Germany
Prior art keywords
preparation
intermediates
analgesic activity
stereoselective process
central analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69127846T
Other languages
English (en)
Other versions
DE69127846T2 (de
Inventor
Mauro Napoletano
Gian Carlo Grancini
Carlo Veneziani
Dario Chiarino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Application granted granted Critical
Publication of DE69127846D1 publication Critical patent/DE69127846D1/de
Publication of DE69127846T2 publication Critical patent/DE69127846T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
DE69127846T 1990-03-28 1991-03-08 Stereoselektives Verfahren zur Herstellung von 2-Amino-Ethanol-Derivaten mit zentralanalgetischer Aktivität und Zwischenprodukten Expired - Fee Related DE69127846T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19856A IT1239950B (it) 1990-03-28 1990-03-28 Processo per la preparazione di composti con attivita' analgesica centrale

Publications (2)

Publication Number Publication Date
DE69127846D1 true DE69127846D1 (de) 1997-11-13
DE69127846T2 DE69127846T2 (de) 1998-05-14

Family

ID=11161831

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69127846T Expired - Fee Related DE69127846T2 (de) 1990-03-28 1991-03-08 Stereoselektives Verfahren zur Herstellung von 2-Amino-Ethanol-Derivaten mit zentralanalgetischer Aktivität und Zwischenprodukten

Country Status (6)

Country Link
US (1) US5142066A (de)
EP (1) EP0449011B1 (de)
JP (1) JPH06279400A (de)
AT (1) ATE159011T1 (de)
DE (1) DE69127846T2 (de)
IT (1) IT1239950B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069793A2 (en) 2003-01-28 2004-08-19 Bristol-Myers Squibb Company Novel 2-substituted cyclic amines as calcium sensing receptor modulators
US7205322B2 (en) 2003-02-12 2007-04-17 Bristol-Myers Squibb Company Thiazolidine compounds as calcium sensing receptor modulators
US7265145B2 (en) 2003-05-28 2007-09-04 Bristol-Myers Squibb Company Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775431A (en) * 1970-12-30 1973-11-27 Mobil Oil Corp Pyrrolidones from ypsilon-butyrolactones using a zeolite catalyst
DE3789557T2 (de) * 1986-07-31 1994-11-03 Nippon Catalytic Chem Ind Verfahren zur Herstellung von Maleimid.
US4999360A (en) * 1987-12-21 1991-03-12 Monsanto Company Method of inhibiting virus
DE3813416A1 (de) * 1988-04-21 1989-11-02 Hoechst Ag 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
IE61631B1 (en) * 1988-05-20 1994-11-16 Zambon Spa Compounds with central analgesic activity, process for their preparation and pharmaceutical compositions containing them
DD279669A1 (de) * 1989-01-31 1990-06-13 Akad Wissenschaften Ddr Verfahren zur herstellung von 1-aryl-3,5-bis(arylamino)-4-halogen-3-pyrrolin-2-onen

Also Published As

Publication number Publication date
IT1239950B (it) 1993-11-27
IT9019856A0 (it) 1990-03-28
ATE159011T1 (de) 1997-10-15
IT9019856A1 (it) 1991-09-28
JPH06279400A (ja) 1994-10-04
EP0449011B1 (de) 1997-10-08
EP0449011A2 (de) 1991-10-02
EP0449011A3 (en) 1992-05-27
DE69127846T2 (de) 1998-05-14
US5142066A (en) 1992-08-25

Similar Documents

Publication Publication Date Title
ATE150462T1 (de) Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung
ATE85608T1 (de) Verbindungen mit biologischer aktivitaet.
DE3775882D1 (de) Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeuren ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
ATE160341T1 (de) Benzolsulfonamid-derivate und verfahren zur herstellung
EA199800477A1 (ru) Производные хинолина
PT101077A (pt) Processo para a preparacao de derivados de tiazolidinodiona susbtituidos
DE69009195D1 (de) Isoxazol-Derivate mit Anti-Serotonin-Aktivität, deren Herstellungsverfahren und diese enthaltende Zusammensetzungen.
DE68928174D1 (de) Verfahren zur Herstellung von Cephemderivaten
ATE92489T1 (de) Imid-derivate, ihre herstellung und verwendung.
DE3586649D1 (de) Verwendung von spergualinderivaten zur herstellung von arzneimitteln mit immunodepressiver wirkung.
DE69127846D1 (de) Stereoselektives Verfahren zur Herstellung von 2-Amino-Ethanol-Derivaten mit zentralanalgetischer Aktivität und Zwischenprodukten
YU47973B (sh) S-enantiomerni glutaramidi i postupak za njihovo dobijanje
DE69625795D1 (de) Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven Eigenschaften, Verfahren zu deren Herstellung und pharmazeutischen Zusammenstellungen, die sie enthalten
ATE88176T1 (de) 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
ATE126510T1 (de) Herstellung von isochinolinderivaten.
ATE100102T1 (de) Substituierte derivate von 20,21dinoreburnamenin, verfahren zur herstellung und so hergestellte zwischenprodukte, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
ATE229504T1 (de) Verfahren zur herstellung von 3-amino-2-oxo- pyrrolidinen, zwischenprodukte und deren verwendung
ATE38671T1 (de) Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.
IT1229846B (it) Esteri di catecolammine.
DE69109953D1 (de) Alfa-fluorocarbonsäurederivate als Zwischenprodukte zur Herstellung von Fungiziden.
ES2195996T3 (es) Compuestos de hidroxipropionitrilo ciclohexapeptidilo.
FR2677647B1 (fr) Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
ATE66671T1 (de) Gamma-l-glutanyl-4-nitoanilid-derivate und verfahren zur bestimmung von gamma-gtp-aktivitaet unter verwendung dieser derivate.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee