DE69127549D1 - 5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonist - Google Patents
5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonistInfo
- Publication number
- DE69127549D1 DE69127549D1 DE69127549T DE69127549T DE69127549D1 DE 69127549 D1 DE69127549 D1 DE 69127549D1 DE 69127549 T DE69127549 T DE 69127549T DE 69127549 T DE69127549 T DE 69127549T DE 69127549 D1 DE69127549 D1 DE 69127549D1
- Authority
- DE
- Germany
- Prior art keywords
- cycloheptene
- dibenzo
- receptor antagonist
- muscarinic receptor
- muscarinic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/31—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by at least three rings
- C07C211/32—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by at least three rings containing dibenzocycloheptane or dibenzocycloheptene ring systems or condensed derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP90401332 | 1990-05-18 | ||
PCT/US1991/002914 WO1991017973A1 (en) | 1990-05-18 | 1991-04-25 | 5H-DIBENZO(a,d)CYCLOHEPTENES AS MUSCARINIC RECEPTOR ANTAGONISTS |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69127549D1 true DE69127549D1 (de) | 1997-10-09 |
DE69127549T2 DE69127549T2 (de) | 1998-04-23 |
Family
ID=8205710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69127549T Expired - Lifetime DE69127549T2 (de) | 1990-05-18 | 1991-04-25 | 5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonist |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0581767B1 (de) |
JP (1) | JPH05508399A (de) |
AU (1) | AU7957191A (de) |
DE (1) | DE69127549T2 (de) |
ES (1) | ES2109268T3 (de) |
WO (1) | WO1991017973A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508280A (en) * | 1990-05-18 | 1996-04-16 | Merrell Pharmaceuticals, Inc. | 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists |
GB9400600D0 (en) * | 1994-01-14 | 1994-03-09 | Pfizer Ltd | Treatment of motion seckness |
KR100700440B1 (ko) | 2005-01-14 | 2007-03-27 | 네오뷰코오롱 주식회사 | 청색 발광 유기 화합물 및 이를 포함하는 유기 발광다이오드 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA958643A (en) * | 1970-07-07 | 1974-12-03 | Frosst (Charles E.) And Co. | Pharmaceutical compositions containing cyclobenzaprine |
US3828034A (en) * | 1972-05-25 | 1974-08-06 | Syntex Inc | Tricyclic pharmacological agents,intermediates and methods of making |
ES8502099A1 (es) * | 1983-08-02 | 1984-12-16 | Espanola Farma Therapeut | Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina. |
-
1991
- 1991-04-25 WO PCT/US1991/002914 patent/WO1991017973A1/en active IP Right Grant
- 1991-04-25 DE DE69127549T patent/DE69127549T2/de not_active Expired - Lifetime
- 1991-04-25 EP EP91911520A patent/EP0581767B1/de not_active Expired - Lifetime
- 1991-04-25 AU AU79571/91A patent/AU7957191A/en not_active Abandoned
- 1991-04-25 JP JP3510147A patent/JPH05508399A/ja active Pending
- 1991-04-25 ES ES91911520T patent/ES2109268T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH05508399A (ja) | 1993-11-25 |
ES2109268T3 (es) | 1998-01-16 |
EP0581767B1 (de) | 1997-09-03 |
AU7957191A (en) | 1991-12-10 |
WO1991017973A1 (en) | 1991-11-28 |
EP0581767A1 (de) | 1994-02-09 |
DE69127549T2 (de) | 1998-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: AVENTIS INC. (N.D.GES.D. STAATES PENNSYLVANIA), GR |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: AVENTISUB II INC., GREENVILLE, DEL., US |