DE69126593T2 - Heterozyklische Säuren - Google Patents

Heterozyklische Säuren

Info

Publication number
DE69126593T2
DE69126593T2 DE69126593T DE69126593T DE69126593T2 DE 69126593 T2 DE69126593 T2 DE 69126593T2 DE 69126593 T DE69126593 T DE 69126593T DE 69126593 T DE69126593 T DE 69126593T DE 69126593 T2 DE69126593 T2 DE 69126593T2
Authority
DE
Germany
Prior art keywords
thromboxane
formula
group
alkyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69126593T
Other languages
English (en)
Other versions
DE69126593D1 (de
Inventor
Alan Wellington Faull
Keith Russell
William John Watkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of DE69126593D1 publication Critical patent/DE69126593D1/de
Application granted granted Critical
Publication of DE69126593T2 publication Critical patent/DE69126593T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69126593T 1990-10-04 1991-09-26 Heterozyklische Säuren Expired - Fee Related DE69126593T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909021571A GB9021571D0 (en) 1990-10-04 1990-10-04 Heterocyclic acids

Publications (2)

Publication Number Publication Date
DE69126593D1 DE69126593D1 (de) 1997-07-24
DE69126593T2 true DE69126593T2 (de) 1997-10-02

Family

ID=10683219

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69126593T Expired - Fee Related DE69126593T2 (de) 1990-10-04 1991-09-26 Heterozyklische Säuren

Country Status (19)

Country Link
US (2) US5219874A (de)
EP (1) EP0482771B1 (de)
JP (1) JPH04273871A (de)
KR (1) KR100191763B1 (de)
AT (1) ATE154603T1 (de)
AU (1) AU646493B2 (de)
CA (1) CA2052294A1 (de)
DE (1) DE69126593T2 (de)
DK (1) DK0482771T3 (de)
ES (1) ES2103301T3 (de)
FI (1) FI914621A (de)
GB (2) GB9021571D0 (de)
GR (1) GR3023804T3 (de)
IE (1) IE913111A1 (de)
IL (1) IL99441A (de)
NO (1) NO303781B1 (de)
NZ (1) NZ239698A (de)
PT (1) PT99153B (de)
ZA (1) ZA917066B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
KR960706358A (ko) * 1993-12-17 1996-12-09 폴지. 라피아티스 아이코사노이드 형성을 억제하는 안티센스 올리고뉴클레오타이드(Antisense Oligonucleotides to Suppress Elcosanoid Formation)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58150575A (ja) * 1982-03-04 1983-09-07 Chugai Pharmaceut Co Ltd 新規なプロスタグランジン誘導体
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8330097D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cyclic ethers
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8330120D0 (en) * 1983-11-11 1983-12-21 Ici Plc Chemical process
GB8330099D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cycloalkane derivatives
GB8511894D0 (en) * 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
HU198706B (en) * 1985-05-10 1989-11-28 Ici Plc Process for producing 1,3-dioxan-ethers and pharmaceutical compositions containing them
ES8802508A1 (es) * 1985-05-10 1988-07-16 Ici Plc Procedimiento para preparar derivados alquenicos.
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
ATE56967T1 (de) * 1985-11-12 1990-10-15 Ici Plc Amidderivate.
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
EP0346511A1 (de) * 1988-06-15 1989-12-20 Fujisawa Pharmaceutical Co., Ltd. Sauerstoff enthaltende heterozyklische Verbindung, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
GB8814340D0 (en) * 1988-06-16 1988-07-20 Ici Plc Process
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
AU6307690A (en) * 1989-09-27 1991-04-11 Rhone-Poulenc Sante Imidazoles
KR910006904B1 (ko) * 1989-10-16 1991-09-10 한국과학기술연구원 새로운 에스테르 화합물 및 그의 제조방법

Also Published As

Publication number Publication date
NZ239698A (en) 1994-03-25
DE69126593D1 (de) 1997-07-24
AU646493B2 (en) 1994-02-24
NO913886L (no) 1992-04-06
US5219874A (en) 1993-06-15
IE913111A1 (en) 1992-04-08
JPH04273871A (ja) 1992-09-30
FI914621A0 (fi) 1991-10-02
GB9118729D0 (en) 1991-10-16
EP0482771A2 (de) 1992-04-29
PT99153B (pt) 1999-04-30
EP0482771A3 (en) 1992-07-01
FI914621A (fi) 1992-04-05
DK0482771T3 (da) 1998-01-26
ATE154603T1 (de) 1997-07-15
NO913886D0 (no) 1991-10-03
GR3023804T3 (en) 1997-09-30
IL99441A0 (en) 1992-08-18
CA2052294A1 (en) 1992-04-05
GB9021571D0 (en) 1990-11-21
KR100191763B1 (ko) 1999-06-15
AU8372791A (en) 1993-03-18
KR920008022A (ko) 1992-05-27
IL99441A (en) 1996-12-05
PT99153A (pt) 1992-09-30
ES2103301T3 (es) 1997-09-16
US5410064A (en) 1995-04-25
EP0482771B1 (de) 1997-06-18
ZA917066B (en) 1992-06-24
NO303781B1 (no) 1998-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee