IL99441A - 1,3 dioxane-5-YL-5 (thiazolyl or imidazolyl) alkenoic acid derivatives their preparation and pharmaceutical compositions containing them - Google Patents

1,3 dioxane-5-YL-5 (thiazolyl or imidazolyl) alkenoic acid derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL99441A
IL99441A IL9944191A IL9944191A IL99441A IL 99441 A IL99441 A IL 99441A IL 9944191 A IL9944191 A IL 9944191A IL 9944191 A IL9944191 A IL 9944191A IL 99441 A IL99441 A IL 99441A
Authority
IL
Israel
Prior art keywords
formula
compound
methyl
group
solution
Prior art date
Application number
IL9944191A
Other languages
English (en)
Other versions
IL99441A0 (en
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL99441A0 publication Critical patent/IL99441A0/xx
Publication of IL99441A publication Critical patent/IL99441A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL9944191A 1990-10-04 1991-09-08 1,3 dioxane-5-YL-5 (thiazolyl or imidazolyl) alkenoic acid derivatives their preparation and pharmaceutical compositions containing them IL99441A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909021571A GB9021571D0 (en) 1990-10-04 1990-10-04 Heterocyclic acids

Publications (2)

Publication Number Publication Date
IL99441A0 IL99441A0 (en) 1992-08-18
IL99441A true IL99441A (en) 1996-12-05

Family

ID=10683219

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9944191A IL99441A (en) 1990-10-04 1991-09-08 1,3 dioxane-5-YL-5 (thiazolyl or imidazolyl) alkenoic acid derivatives their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (2) US5219874A (de)
EP (1) EP0482771B1 (de)
JP (1) JPH04273871A (de)
KR (1) KR100191763B1 (de)
AT (1) ATE154603T1 (de)
AU (1) AU646493B2 (de)
CA (1) CA2052294A1 (de)
DE (1) DE69126593T2 (de)
DK (1) DK0482771T3 (de)
ES (1) ES2103301T3 (de)
FI (1) FI914621A7 (de)
GB (2) GB9021571D0 (de)
GR (1) GR3023804T3 (de)
IE (1) IE913111A1 (de)
IL (1) IL99441A (de)
NO (1) NO303781B1 (de)
NZ (1) NZ239698A (de)
PT (1) PT99153B (de)
ZA (1) ZA917066B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
CA2179168A1 (en) * 1993-12-17 1995-06-22 Douglas A. Kniss Antisense oligonucleotides to suppress eicosanoid formation

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58150575A (ja) * 1982-03-04 1983-09-07 Chugai Pharmaceut Co Ltd 新規なプロスタグランジン誘導体
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8330099D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cycloalkane derivatives
GB8330097D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cyclic ethers
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8330120D0 (en) * 1983-11-11 1983-12-21 Ici Plc Chemical process
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
HU198706B (en) * 1985-05-10 1989-11-28 Ici Plc Process for producing 1,3-dioxan-ethers and pharmaceutical compositions containing them
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
GB8511894D0 (en) * 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
DE3685775T2 (de) * 1985-05-10 1993-01-21 Ici Plc Alkenderivate.
WO1987002983A1 (en) * 1985-11-12 1987-05-21 Imperial Chemical Industries Plc Amide derivatives
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
EP0346511A1 (de) * 1988-06-15 1989-12-20 Fujisawa Pharmaceutical Co., Ltd. Sauerstoff enthaltende heterozyklische Verbindung, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
GB8814340D0 (en) * 1988-06-16 1988-07-20 Ici Plc Process
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
IL95760A0 (en) * 1989-09-27 1992-05-25 Rhone Poulenc Sante Imidazole derivatives,their preparation and pharmaceutical compositions containing the same
KR910006904B1 (ko) * 1989-10-16 1991-09-10 한국과학기술연구원 새로운 에스테르 화합물 및 그의 제조방법

Also Published As

Publication number Publication date
KR100191763B1 (ko) 1999-06-15
NO913886D0 (no) 1991-10-03
GB9118729D0 (en) 1991-10-16
PT99153B (pt) 1999-04-30
IE913111A1 (en) 1992-04-08
GB9021571D0 (en) 1990-11-21
FI914621A7 (fi) 1992-04-05
NZ239698A (en) 1994-03-25
KR920008022A (ko) 1992-05-27
JPH04273871A (ja) 1992-09-30
PT99153A (pt) 1992-09-30
DE69126593D1 (de) 1997-07-24
FI914621A0 (fi) 1991-10-02
NO303781B1 (no) 1998-08-31
NO913886L (no) 1992-04-06
IL99441A0 (en) 1992-08-18
ES2103301T3 (es) 1997-09-16
AU646493B2 (en) 1994-02-24
EP0482771A3 (en) 1992-07-01
EP0482771B1 (de) 1997-06-18
AU8372791A (en) 1993-03-18
EP0482771A2 (de) 1992-04-29
ATE154603T1 (de) 1997-07-15
GR3023804T3 (en) 1997-09-30
ZA917066B (en) 1992-06-24
CA2052294A1 (en) 1992-04-05
DE69126593T2 (de) 1997-10-02
DK0482771T3 (da) 1998-01-26
US5219874A (en) 1993-06-15
US5410064A (en) 1995-04-25

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees