DE69122545T2 - Verfahren zur Herstellung von menschlichem Nervenwachstumsfaktor durch Genmanipulation - Google Patents

Verfahren zur Herstellung von menschlichem Nervenwachstumsfaktor durch Genmanipulation

Info

Publication number
DE69122545T2
DE69122545T2 DE1991622545 DE69122545T DE69122545T2 DE 69122545 T2 DE69122545 T2 DE 69122545T2 DE 1991622545 DE1991622545 DE 1991622545 DE 69122545 T DE69122545 T DE 69122545T DE 69122545 T2 DE69122545 T2 DE 69122545T2
Authority
DE
Germany
Prior art keywords
production
growth factor
genetic engineering
nerve growth
human nerve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE1991622545
Other languages
English (en)
Other versions
DE69122545D1 (de
Inventor
Norio Shimizu
Kiyoshi Fujimori
Shinichi Fukuzono
Naoe Kotomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Application granted granted Critical
Publication of DE69122545D1 publication Critical patent/DE69122545D1/de
Publication of DE69122545T2 publication Critical patent/DE69122545T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1991622545 1990-02-21 1991-02-21 Verfahren zur Herstellung von menschlichem Nervenwachstumsfaktor durch Genmanipulation Expired - Fee Related DE69122545T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3835890A JPH03244385A (ja) 1990-02-21 1990-02-21 ヒト神経成長因子の遺伝子工学的生産方法

Publications (2)

Publication Number Publication Date
DE69122545D1 DE69122545D1 (de) 1996-11-14
DE69122545T2 true DE69122545T2 (de) 1997-04-24

Family

ID=12523059

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1991622545 Expired - Fee Related DE69122545T2 (de) 1990-02-21 1991-02-21 Verfahren zur Herstellung von menschlichem Nervenwachstumsfaktor durch Genmanipulation

Country Status (3)

Country Link
EP (1) EP0458437B1 (de)
JP (1) JPH03244385A (de)
DE (1) DE69122545T2 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161152C (da) * 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat
JPH01211490A (ja) * 1988-02-19 1989-08-24 Tosoh Corp ヒト神経成長因子遺伝子セグメント
DE68915841T2 (de) * 1988-03-30 1995-02-02 Hitachi Ltd Verfahren zur Herstellung von Epidermal-Wachstumsfaktor durch genetische Transformation.

Also Published As

Publication number Publication date
JPH03244385A (ja) 1991-10-31
DE69122545D1 (de) 1996-11-14
EP0458437A1 (de) 1991-11-27
EP0458437B1 (de) 1996-10-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee