DE69109676D1 - Verminderung von kardiovaskulären gefässverschlüssen mit ascorbat und hemmstoffen der bindung von lipoprotein (a). - Google Patents

Verminderung von kardiovaskulären gefässverschlüssen mit ascorbat und hemmstoffen der bindung von lipoprotein (a).

Info

Publication number
DE69109676D1
DE69109676D1 DE69109676T DE69109676T DE69109676D1 DE 69109676 D1 DE69109676 D1 DE 69109676D1 DE 69109676 T DE69109676 T DE 69109676T DE 69109676 T DE69109676 T DE 69109676T DE 69109676 D1 DE69109676 D1 DE 69109676D1
Authority
DE
Germany
Prior art keywords
ascorbate
inhibitors
vessel closure
reducing cardiovascular
lipoprotein binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69109676T
Other languages
English (en)
Other versions
DE69109676T2 (de
Inventor
Matthias Rath
Linus C Pauling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MATTHIAS RATH INC., ELDORADO HILLS,, CALIF., US
Original Assignee
Therapy 2000
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/556,968 external-priority patent/US5230996A/en
Priority claimed from US07/557,516 external-priority patent/US5278189A/en
Application filed by Therapy 2000 filed Critical Therapy 2000
Publication of DE69109676D1 publication Critical patent/DE69109676D1/de
Application granted granted Critical
Publication of DE69109676T2 publication Critical patent/DE69109676T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69109676T 1990-06-04 1991-06-03 Verminderung von kardiovaskulären gefässverschlüssen mit ascorbat und hemmstoffen der bindung von lipoprotein (a). Expired - Fee Related DE69109676T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53312990A 1990-06-04 1990-06-04
US07/556,968 US5230996A (en) 1990-06-04 1990-07-24 Use of ascorbate and tranexamic acid solution for organ and blood vessel treatment prior to transplantation
US07/557,516 US5278189A (en) 1990-06-04 1990-07-24 Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A)
PCT/US1991/003876 WO1991019488A1 (en) 1990-06-04 1991-06-03 REDUCTION OF CARDIOVASCULAR VESSEL OCCLUSIONS WITH ASCORBATE AND LIPOPROTEIN (a) BINDING INHIBITORS

Publications (2)

Publication Number Publication Date
DE69109676D1 true DE69109676D1 (de) 1995-06-14
DE69109676T2 DE69109676T2 (de) 1996-02-08

Family

ID=27415114

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69109676T Expired - Fee Related DE69109676T2 (de) 1990-06-04 1991-06-03 Verminderung von kardiovaskulären gefässverschlüssen mit ascorbat und hemmstoffen der bindung von lipoprotein (a).

Country Status (4)

Country Link
EP (1) EP0532706B1 (de)
AU (1) AU8416391A (de)
DE (1) DE69109676T2 (de)
WO (1) WO1991019488A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1068868A3 (de) * 1997-07-08 2001-01-31 Rath, Matthias, Dr. med. Synergistischer Zusammensetzung, der Ascorbat und Lysin für Zustände enthält zur Behandlung extrazellularer Matrixdegeneration
EP0891771A1 (de) * 1997-07-08 1999-01-20 Health Now, Inc. Lysin und Ascorbat oder ihre Derivate zur Behandlung von kardiovaskulären Erkrankungen
JP2001247458A (ja) * 2000-03-08 2001-09-11 Hamari Chemicals Ltd トラネキサム酸亜鉛化合物を含む糖尿病治療剤
US6974833B2 (en) 2001-01-16 2005-12-13 Matthias Rath Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration
ES2184593B2 (es) * 2001-01-16 2005-05-01 Matthias Rath Uso de composiciones que comprenden inhibidores de la fibrinolisis y compuestos de ascorbato para el tratamiento del cancer.
BR0205944A (pt) * 2001-08-24 2004-12-28 Matthias Rath Compostos de ácido ascórbico, métodos de sìntese e suas aplicações
WO2003017942A2 (en) * 2001-08-24 2003-03-06 Rath Matthias M D Ascorbic acid derivatives with amino acids
EP1380290A1 (de) * 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-Beta-Strukturweg und seine therapeutische Relevanz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954521A (en) * 1976-07-01 1990-09-04 Sawyer Philip Nicholas Methods for administering anti-thrombotic compounds
JPS6078560A (ja) * 1983-10-04 1985-05-04 Kongo Yakuhin Kk 無酸味強化栄養剤
JP2618657B2 (ja) * 1987-10-02 1997-06-11 株式会社資生堂 抗色素沈着外用剤

Also Published As

Publication number Publication date
EP0532706B1 (de) 1995-05-10
AU8416391A (en) 1992-01-07
EP0532706A4 (en) 1993-06-30
EP0532706A1 (de) 1993-03-24
DE69109676T2 (de) 1996-02-08
WO1991019488A1 (en) 1991-12-26

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: HEALTH NOW, SAN FRANCISCO, CALIF., US

8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: ACKMANN, MENGES & DEMSKI PATENTANWAELTE, 80469 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: MATTHIAS RATH INC., ELDORADO HILLS,, CALIF., US

8328 Change in the person/name/address of the agent

Free format text: C. KLEINER UND KOLLEGEN, 70178 STUTTGART

8339 Ceased/non-payment of the annual fee