DE69109592D1 - Pyrazoloquinolinderivate. - Google Patents

Pyrazoloquinolinderivate.

Info

Publication number
DE69109592D1
DE69109592D1 DE69109592T DE69109592T DE69109592D1 DE 69109592 D1 DE69109592 D1 DE 69109592D1 DE 69109592 T DE69109592 T DE 69109592T DE 69109592 T DE69109592 T DE 69109592T DE 69109592 D1 DE69109592 D1 DE 69109592D1
Authority
DE
Germany
Prior art keywords
alkyl group
lower alkyl
hydrogen atom
activity
pyrazoloquinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69109592T
Other languages
English (en)
Other versions
DE69109592T2 (de
Inventor
Fumio Suzuki
Yoshisuke Nakasato
Kenji Ohmori
Tadafumi Tamura
Hisashi Hosoe
Kazuhiro Kubo
Ikufumi Yoshitake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE69109592D1 publication Critical patent/DE69109592D1/de
Application granted granted Critical
Publication of DE69109592T2 publication Critical patent/DE69109592T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69109592T 1990-09-14 1991-09-13 Pyrazoloquinolinderivate. Expired - Fee Related DE69109592T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24538990 1990-09-14

Publications (2)

Publication Number Publication Date
DE69109592D1 true DE69109592D1 (de) 1995-06-14
DE69109592T2 DE69109592T2 (de) 1995-10-05

Family

ID=17132930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69109592T Expired - Fee Related DE69109592T2 (de) 1990-09-14 1991-09-13 Pyrazoloquinolinderivate.

Country Status (7)

Country Link
US (1) US5192768A (de)
EP (1) EP0476544B1 (de)
AT (1) ATE122351T1 (de)
CA (1) CA2051310C (de)
DE (1) DE69109592T2 (de)
DK (1) DK0476544T3 (de)
ES (1) ES2072503T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194515A (ja) * 1991-07-31 1993-08-03 Kyowa Hakko Kogyo Co Ltd 縮合ナフチリジン誘導体
US5281610A (en) * 1991-07-31 1994-01-25 Kyowa Hakko Kogyo Co., Ltd. Condensed naphthyridine derivatives
TW304945B (de) * 1992-06-27 1997-05-11 Hoechst Ag
US6909001B2 (en) * 2002-12-12 2005-06-21 Pharmacia Corporation Method of making tricyclic aminocyanopyridine compounds
US20040127519A1 (en) * 2002-12-12 2004-07-01 Pharmacia Corporation Method of using aminocyanopyridine compounds as mitogen activated protein kinase-activated protein kinase-2 inhibitors
US20040142978A1 (en) * 2002-12-12 2004-07-22 Pharmacia Corporation Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
WO2005028474A2 (en) * 2003-05-29 2005-03-31 Millennium Pharmaceuticals, Inc. Pyrazoloquinoline derivatives as chk-1 inhibitors
WO2005080392A1 (ja) 2004-02-19 2005-09-01 Takeda Pharmaceutical Company Limited ピラゾロキノロン誘導体およびその用途
EA023493B1 (ru) 2010-09-07 2016-06-30 Астеллас Фарма Инк. Производное пиразолохинолина
CN111514144B (zh) 2015-05-26 2021-10-26 高雄医学大学 具抑制细菌葡萄糖醛酸酶活性的吡唑并[4,3-c]喹啉衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524146A (en) * 1982-12-08 1985-06-18 Ciba-Geigy Corporation Certain -2-heterocycle substituted pyrazoloquinolines
PH21213A (en) * 1984-10-26 1987-08-21 Fujisawa Pharmaceutical Co Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same
US4748246A (en) * 1987-05-07 1988-05-31 American Home Products Corporation Pyrazolo(4,3-c)quinolines

Also Published As

Publication number Publication date
US5192768A (en) 1993-03-09
CA2051310C (en) 2001-04-10
DK0476544T3 (da) 1995-08-07
ES2072503T3 (es) 1995-07-16
EP0476544A1 (de) 1992-03-25
CA2051310A1 (en) 1992-03-15
ATE122351T1 (de) 1995-05-15
EP0476544B1 (de) 1995-05-10
DE69109592T2 (de) 1995-10-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee