DE69105094D1 - Wässriges Gel von Retinsäure und Hydroxypropyl-beta-Zyklodextrin. - Google Patents

Wässriges Gel von Retinsäure und Hydroxypropyl-beta-Zyklodextrin.

Info

Publication number
DE69105094D1
DE69105094D1 DE69105094T DE69105094T DE69105094D1 DE 69105094 D1 DE69105094 D1 DE 69105094D1 DE 69105094 T DE69105094 T DE 69105094T DE 69105094 T DE69105094 T DE 69105094T DE 69105094 D1 DE69105094 D1 DE 69105094D1
Authority
DE
Germany
Prior art keywords
retinoic acid
aqueous gel
gel
beta cyclodextrin
hydroxypropyl beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69105094T
Other languages
English (en)
Other versions
DE69105094T2 (de
Inventor
Alain Rolland
Braham Shroot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Centre International de Recherches Dermatologiques Galderma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre International de Recherches Dermatologiques Galderma filed Critical Centre International de Recherches Dermatologiques Galderma
Application granted granted Critical
Publication of DE69105094D1 publication Critical patent/DE69105094D1/de
Publication of DE69105094T2 publication Critical patent/DE69105094T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Nanotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69105094T 1990-11-15 1991-11-14 Wässriges Gel von Retinsäure und Hydroxypropyl-beta-Zyklodextrin. Expired - Fee Related DE69105094T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU87843A LU87843A1 (fr) 1990-11-15 1990-11-15 Gel aqueux a base d'acide retinoique et d'hydroxypropyl-beta-cyclodextrine et son utilisation en medecine humaine et en cosmetique

Publications (2)

Publication Number Publication Date
DE69105094D1 true DE69105094D1 (de) 1994-12-15
DE69105094T2 DE69105094T2 (de) 1995-05-18

Family

ID=19731263

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69105094T Expired - Fee Related DE69105094T2 (de) 1990-11-15 1991-11-14 Wässriges Gel von Retinsäure und Hydroxypropyl-beta-Zyklodextrin.

Country Status (8)

Country Link
EP (1) EP0486395B1 (de)
JP (1) JP2650805B2 (de)
AT (1) ATE113831T1 (de)
CA (1) CA2055578A1 (de)
DE (1) DE69105094T2 (de)
DK (1) DK0486395T3 (de)
ES (1) ES2064958T3 (de)
LU (1) LU87843A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2047456B1 (es) * 1992-07-31 1994-10-01 Herrando Carlos Postigo Composicion para la obtencion de un producto cosmetico y productos similares.
SE9300971D0 (sv) * 1993-03-24 1993-03-24 Jan Wadstein Hudvaardskomposition
ES2083333B1 (es) * 1994-09-22 1997-01-16 Corral Begona Gozalo Crema para el tratamiento de la psoriasis.
DE69828620T2 (de) 1997-02-25 2005-12-01 The Regents Of The University Of Michigan, Ann Arbor Verfahren und zusammensetzungen zur vorbeugung und behandlung der chronologischer alterung der menschliches haut
WO1998050012A1 (en) * 1997-05-02 1998-11-12 Gist-Brocades B.V. Stable vitamin c concentrates
JP2002523475A (ja) * 1998-09-02 2002-07-30 アラーガン・セイルズ・インコーポレイテッド 防腐したシクロデキストリン含有組成物
KR20050084267A (ko) * 2002-12-12 2005-08-26 갈데르마 리써어치 앤드 디벨로프먼트,에스.엔.씨. 페놀성 유도체 및 레티노이드를 포함하는 수성-알코올성탈색 겔
JP4781680B2 (ja) * 2005-01-17 2011-09-28 株式会社Ａｄｅｋａ 防腐剤組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
GB8910069D0 (en) * 1989-05-03 1989-06-21 Janssen Pharmaceutica Nv Method of topically treating acne vulgaris
FR2647015B1 (fr) * 1989-05-17 1994-05-06 Cird Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique

Also Published As

Publication number Publication date
DE69105094T2 (de) 1995-05-18
ES2064958T3 (es) 1995-02-01
JP2650805B2 (ja) 1997-09-10
LU87843A1 (fr) 1992-08-25
JPH0656622A (ja) 1994-03-01
EP0486395A1 (de) 1992-05-20
CA2055578A1 (fr) 1992-05-16
ATE113831T1 (de) 1994-11-15
EP0486395B1 (de) 1994-11-09
DK0486395T3 (da) 1995-04-24

Similar Documents

Publication Publication Date Title
CA2165613A1 (fr) Composition cosmetique, dermatologique ou pharmaceutique stable contenant du disulfure de selenium et au moins un sel de zinc
BR9709079A (pt) Composição cosmética para rejuvenescimento da pele sem irritação da mesma
DE59410301D1 (de) Topische zubereitungen mit einem gehalt an l-arginin
MY105521A (en) Moisturizing vehicle for topical application of vitamin a acid.
ATE96651T1 (de) Kosmetisches praeparat.
DE69105094T2 (de) Wässriges Gel von Retinsäure und Hydroxypropyl-beta-Zyklodextrin.
DE69917858D1 (de) Gebrauch von Silicongummi zur Stabilisierung von Ascorbinsaüre und Vorbereitungen die diese Zusammensetzungen enthalten
DE69939721D1 (de) Fulvinsäure und deren Verwendung in der Behandlung von Candida Infektionen
NO175883C (no) Fremgangsmåte for fremstilling av et preparat i vandig gelform for topisk anbringelse
DK0631772T3 (da) Retinoidholdig sammensætning
ATE221780T1 (de) Fenbendazolformulierungen
ATE160088T1 (de) Topische wässrige gele oder suspension auf basis von pulverisiertem vulkanischen oder diagenischem minerale
TR199700694T1 (xx) D vitamini t�revlerinin dermotolojik kullan�m�.
NO173705C (no) Kosmetisk preparat for topisk paafoering
FR2416009A1 (fr) Substance cosmetique active a base de proteines de la peau
FI910112A0 (fi) Preparat foer lokalt bruk.
NO303666B1 (no) Preparat for lokal anvendelse, fremgangsmåte for fremstilling av slike, samt anvendelse av disse
DE69018570D1 (de) Wasserlösliche Vitamin A-Zubereitungen und deren Verwendung bei der Hautbehandlung.
ITMI912466A1 (it) Uso di 1, 2 dipalmitoil-l-alfa-fosfatidil-n, n-dimetiletanolammina, in composizioni dermatologiche
FR2612774B1 (fr) Compositions cosmetiques et pharmaceutiques, utilisees pour traiter le processus de l'alopecie androgenogenetique, contenant de l'acide azelaique
DE59801192D1 (de) Delta-aminolävulinsäure enthaltendes arzneimittel
GB1402282A (en) Preparation for skin treatment
CO4600670A1 (es) Composiciones topicas acuosas que comprenden un agente anti- acne acido y un glicoleter soluble en agua

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee