DE69026639D1 - Heterozyklische zyklische Ether mit hemmender Wirkung auf 5-Lipoxygenase - Google Patents
Heterozyklische zyklische Ether mit hemmender Wirkung auf 5-LipoxygenaseInfo
- Publication number
- DE69026639D1 DE69026639D1 DE69026639T DE69026639T DE69026639D1 DE 69026639 D1 DE69026639 D1 DE 69026639D1 DE 69026639 T DE69026639 T DE 69026639T DE 69026639 T DE69026639 T DE 69026639T DE 69026639 D1 DE69026639 D1 DE 69026639D1
- Authority
- DE
- Germany
- Prior art keywords
- alkylene
- lipoxygenase
- ring
- inhibitory effect
- sulphinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89400558 | 1989-02-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69026639D1 true DE69026639D1 (de) | 1996-05-30 |
DE69026639T2 DE69026639T2 (de) | 1996-11-14 |
Family
ID=8202929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69026639T Expired - Fee Related DE69026639T2 (de) | 1989-02-28 | 1990-02-23 | Heterozyklische zyklische Ether mit hemmender Wirkung auf 5-Lipoxygenase |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0385679B1 (de) |
JP (1) | JPH02273673A (de) |
AT (1) | ATE137234T1 (de) |
AU (1) | AU626988B2 (de) |
CA (1) | CA2009827A1 (de) |
DE (1) | DE69026639T2 (de) |
ES (1) | ES2085330T3 (de) |
FI (1) | FI901010A0 (de) |
GR (1) | GR3019759T3 (de) |
IL (1) | IL93344A0 (de) |
NO (1) | NO174890C (de) |
NZ (1) | NZ232515A (de) |
PT (1) | PT93289A (de) |
ZA (1) | ZA901043B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089495A (en) * | 1989-01-30 | 1992-02-18 | Imperial Chemical Industries Plc | Heterocyclic thiazole derivatives and pharmaceutical compositions comprising said derivatives |
IE70521B1 (en) * | 1989-02-28 | 1996-12-11 | Zeneca Pharma Sa | Heterocycles with inhibitory activity of 5-lipoxygenase |
IL93343A0 (en) * | 1989-02-28 | 1990-11-29 | Ici Plc | Heterocyclic cycloalkanes |
IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
EP0462831B1 (de) * | 1990-06-21 | 1996-02-28 | Zeneca Limited | Bizyklische Pyran-Derivate und ihre Verwendung als 5-Lipoxygenasehemmer |
IE911919A1 (en) * | 1990-06-21 | 1992-01-01 | Zeneca Ltd | Bicyclic heterocyclic compounds |
IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0540165A1 (de) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkonsäurederivate |
GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5268379A (en) * | 1992-08-24 | 1993-12-07 | Abbott Laboratories | Ether-containing inhibitors of 5-lipoxygenase |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0586229A1 (de) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(Subst.-Alkyl)-Pyrrolidine als 5-Lipoxygenase-Inhibitoren |
IL110280A0 (en) * | 1993-07-27 | 1994-10-21 | Zeneca Ltd | Thiazole derivatives |
EP0636624A1 (de) * | 1993-07-27 | 1995-02-01 | Zeneca Limited | Thiazolederivative als Lipoxygenasehemmer |
US6825221B2 (en) | 2001-10-18 | 2004-11-30 | Allergan, Inc. | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4518416A (en) * | 1982-06-04 | 1985-05-21 | Bayer Aktiengesellschaft | Certain trimethyl silyl-lower-alkyl esters of pyridyloxy-phenoxy-lower alkanoic acids, compositions containing same and herbicidal method of use |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4681940A (en) * | 1985-11-19 | 1987-07-21 | American Home Products Corporation | 5-[3-[[2-quinolyl]methoxy]phenyl]-1,3-oxazoles |
GB8711802D0 (en) * | 1987-05-19 | 1987-06-24 | Fujisawa Pharmaceutical Co | Dithioacetal compounds |
-
1990
- 1990-02-11 IL IL93344A patent/IL93344A0/xx unknown
- 1990-02-12 CA CA002009827A patent/CA2009827A1/en not_active Abandoned
- 1990-02-12 ZA ZA901043A patent/ZA901043B/xx unknown
- 1990-02-13 NZ NZ232515A patent/NZ232515A/en unknown
- 1990-02-14 AU AU49763/90A patent/AU626988B2/en not_active Ceased
- 1990-02-23 EP EP90301987A patent/EP0385679B1/de not_active Expired - Lifetime
- 1990-02-23 DE DE69026639T patent/DE69026639T2/de not_active Expired - Fee Related
- 1990-02-23 ES ES90301987T patent/ES2085330T3/es not_active Expired - Lifetime
- 1990-02-23 AT AT90301987T patent/ATE137234T1/de not_active IP Right Cessation
- 1990-02-27 NO NO900918A patent/NO174890C/no unknown
- 1990-02-28 PT PT93289A patent/PT93289A/pt not_active Application Discontinuation
- 1990-02-28 FI FI901010A patent/FI901010A0/fi not_active Application Discontinuation
- 1990-02-28 JP JP2046013A patent/JPH02273673A/ja active Pending
-
1996
- 1996-04-25 GR GR960400833T patent/GR3019759T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA901043B (en) | 1990-10-31 |
NO174890C (no) | 1994-07-27 |
PT93289A (pt) | 1990-08-31 |
EP0385679A2 (de) | 1990-09-05 |
NO174890B (no) | 1994-04-18 |
NZ232515A (en) | 1992-03-26 |
AU4976390A (en) | 1990-09-06 |
AU626988B2 (en) | 1992-08-13 |
EP0385679A3 (de) | 1991-11-27 |
ATE137234T1 (de) | 1996-05-15 |
IL93344A0 (en) | 1990-11-29 |
NO900918L (no) | 1990-08-29 |
FI901010A0 (fi) | 1990-02-28 |
EP0385679B1 (de) | 1996-04-24 |
NO900918D0 (no) | 1990-02-27 |
DE69026639T2 (de) | 1996-11-14 |
JPH02273673A (ja) | 1990-11-08 |
CA2009827A1 (en) | 1990-08-31 |
GR3019759T3 (en) | 1996-07-31 |
ES2085330T3 (es) | 1996-06-01 |
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Publication | Publication Date | Title |
---|---|---|
DE69026639D1 (de) | Heterozyklische zyklische Ether mit hemmender Wirkung auf 5-Lipoxygenase | |
DE69024076T2 (de) | Heterozyklische Verbindungen mit hemmender Wirkung auf 5-Lipoxygenase | |
ATE110073T1 (de) | Heterozyklische derative. | |
DE69023940D1 (de) | Heterozyklische Zykloalkane mit hemmender Wirkung auf 5-Lipoxygenase. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |