DE69018084D1 - Methoden und zusammensetzungen für heilung von knochen. - Google Patents
Methoden und zusammensetzungen für heilung von knochen.Info
- Publication number
- DE69018084D1 DE69018084D1 DE69018084T DE69018084T DE69018084D1 DE 69018084 D1 DE69018084 D1 DE 69018084D1 DE 69018084 T DE69018084 T DE 69018084T DE 69018084 T DE69018084 T DE 69018084T DE 69018084 D1 DE69018084 D1 DE 69018084D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- compositions
- bone healing
- ghl
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Prostheses (AREA)
- Polyurethanes Or Polyureas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/421,101 US5059588A (en) | 1989-10-13 | 1989-10-13 | Methods and compositions for healing bone using gly his lys: copper |
PCT/US1990/005838 WO1991005797A1 (en) | 1989-10-13 | 1990-10-11 | Methods and compositions for healing bone |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69018084D1 true DE69018084D1 (de) | 1995-04-27 |
DE69018084T2 DE69018084T2 (de) | 1995-07-27 |
Family
ID=23669168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69018084T Expired - Fee Related DE69018084T2 (de) | 1989-10-13 | 1990-10-11 | Methoden und zusammensetzungen für heilung von knochen. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5059588A (de) |
EP (1) | EP0495877B1 (de) |
JP (1) | JPH05501253A (de) |
KR (1) | KR927003079A (de) |
AT (1) | ATE120203T1 (de) |
AU (1) | AU648520B2 (de) |
CA (1) | CA2067505A1 (de) |
DE (1) | DE69018084T2 (de) |
DK (1) | DK0495877T3 (de) |
ES (1) | ES2069750T3 (de) |
FI (1) | FI921609A0 (de) |
NO (1) | NO921454L (de) |
WO (1) | WO1991005797A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5120831A (en) * | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
CA2065299C (en) * | 1989-08-09 | 2001-07-24 | Buck A. Rhodes | Direct radiolabeling of antibodies and other proteins with technetium or rhenium |
US5443816A (en) * | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
US5386012A (en) * | 1990-02-06 | 1995-01-31 | Strid; Lars | Growth factor in connection with artificial implants |
US5643549A (en) * | 1992-02-20 | 1997-07-01 | Rhomed Incorporated | Leukostimulatory agent for in vivo leukocyte tagging |
US5382431A (en) * | 1992-09-29 | 1995-01-17 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
WO1995026192A1 (en) * | 1994-03-28 | 1995-10-05 | Skin Biology, Inc. | Starch-metal complexes for skin and hair |
JPH07316192A (ja) * | 1994-05-27 | 1995-12-05 | Hoechst Japan Ltd | L−リシル−グリシル−l−ヒスチジンおよびこれを含有する創傷治療剤 |
US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
US6331285B1 (en) | 1996-06-05 | 2001-12-18 | Palatin Technologies, Inc. | Structurally determined cyclic metallo-constructs and applications |
US5888522A (en) * | 1996-08-23 | 1999-03-30 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US20030130185A1 (en) * | 2000-09-29 | 2003-07-10 | David Bar-Or | Metal-binding compounds and uses therefor |
CA2385551A1 (en) | 1999-10-01 | 2001-04-12 | Dmi Biosciences, Inc. | Metal-binding compounds and uses therefor |
US7632803B2 (en) * | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US7700660B2 (en) * | 2000-05-31 | 2010-04-20 | Encelle, Inc. | Method of treating chronic ulcers |
US7385025B2 (en) * | 2000-12-19 | 2008-06-10 | Palatin Technologies, Inc. | Metallopeptide compounds |
US20030148927A1 (en) * | 2001-10-05 | 2003-08-07 | Procyte Corporation | Stable solutions of peptide copper complexes and cosmetic and pharmaceutical formulations produced therefrom |
WO2004004671A1 (en) * | 2002-07-02 | 2004-01-15 | Procyte Corporation | Compositions containing peptide copper complexes and soft tissue fillers |
US20040138103A1 (en) * | 2002-11-07 | 2004-07-15 | Procyte Corporation | Compositions containing peptide copper complexes and metalloproteinase inhibitors and methods related thereto |
US20040142853A1 (en) * | 2002-11-07 | 2004-07-22 | Procyte Corporation | Stimulation of hair growth by compositions containing peptide copper complexes and minoxidil |
US7128923B2 (en) * | 2003-03-31 | 2006-10-31 | Procyte Corporation | Preserved and stable compositions containing peptide copper complexes and method related thereto |
US6927205B2 (en) * | 2003-04-28 | 2005-08-09 | Procyte Corporation | Compositions and methods for treatment of psoriasis |
US6927206B2 (en) * | 2003-06-06 | 2005-08-09 | Procyte Corporation | Compositions and methods for treatment of rosacea |
WO2005097061A1 (en) * | 2004-04-01 | 2005-10-20 | Procyte Corporation | Encapsulated peptide copper complexes and compositions and methods related thereto |
US20060052287A1 (en) * | 2004-08-18 | 2006-03-09 | Procyte Corporation | Polyethylene glycol - peptide copper complexes and compositions and methods related thereto |
US7897800B2 (en) | 2006-02-03 | 2011-03-01 | Jr Chem, Llc | Chemical compositions and methods of making them |
WO2007089267A1 (en) | 2006-02-03 | 2007-08-09 | Jr Chem, Llc | Anti-aging treatment using copper and zinc compositions |
US7687650B2 (en) | 2006-02-03 | 2010-03-30 | Jr Chem, Llc | Chemical compositions and methods of making them |
US7867522B2 (en) | 2006-09-28 | 2011-01-11 | Jr Chem, Llc | Method of wound/burn healing using copper-zinc compositions |
US8273791B2 (en) | 2008-01-04 | 2012-09-25 | Jr Chem, Llc | Compositions, kits and regimens for the treatment of skin, especially décolletage |
CA2750636C (en) | 2009-01-23 | 2017-07-25 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3194732A (en) * | 1960-10-03 | 1965-07-13 | Neuhauser Irene | Assisting healing of skin-denuded areas on the body with dried non-fibrous egg-shellmembrane products and compositions therefor |
US3558770A (en) * | 1967-09-01 | 1971-01-26 | Kraftco Corp | Wound treating composition employing an enzyme modified casein |
US3551554A (en) * | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
US3767784A (en) * | 1970-12-01 | 1973-10-23 | S Gluck | Composition for the protection and treatment of injured body tissue and method of utilizing the same |
US3832338A (en) * | 1972-03-23 | 1974-08-27 | Diagnostic Data Inc | Orgotein production using a buffer solution containing divalent metal salts |
US3758682A (en) * | 1972-03-23 | 1973-09-11 | Diagnostics Data Inc | Pharmaceutical compositions comprising orgotein and their use |
US4022888A (en) * | 1975-09-09 | 1977-05-10 | Diagnostic Data, Inc. | Esterified orgotein |
DE2700043C2 (de) * | 1977-01-03 | 1983-12-08 | Thera Gesellschaft für Patentverwertung mbH, 8036 Herrsching | Mittel zur Verbesserung der Durchblutung und Wundheilung |
US4167945A (en) * | 1977-01-31 | 1979-09-18 | Gottlieb Sheldon K | Method for enhancing the healing of grafted tissue |
US4287184A (en) * | 1977-11-23 | 1981-09-01 | The Massachusetts General Hospital | Process for healing wounds |
US4263428A (en) * | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
US4440788A (en) * | 1980-05-13 | 1984-04-03 | Mitsubishi Chemical Industries, Limited | Cysteine derivatives |
US4461724A (en) * | 1981-10-28 | 1984-07-24 | Nippon Zoki Pharmaceutical Co., Ltd. | Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them |
HU193289B (en) * | 1984-06-19 | 1987-09-28 | Universal Vegyipari Szoevetkez | Cosmetical composition for treating hair and nail containing blood plasma concentrate as active agent |
US4760051A (en) * | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
US4937230A (en) * | 1985-01-24 | 1990-06-26 | Procyte Corporation | Method of healing wounds in horses |
US4877770A (en) * | 1985-02-08 | 1989-10-31 | Procyte Corporation | Chemical derivatives of GHL-Cu |
US4810693A (en) * | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
US4767753A (en) * | 1985-02-08 | 1988-08-30 | Procyte Corporation | Methods and compositions for preventing ulcers |
US4665054A (en) * | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
DE3888718T2 (de) * | 1987-04-20 | 1994-07-14 | Procyte Corp | Chemische Derivate von GHL-Cu. |
-
1989
- 1989-10-13 US US07/421,101 patent/US5059588A/en not_active Expired - Fee Related
-
1990
- 1990-10-11 KR KR1019920700849A patent/KR927003079A/ko not_active Application Discontinuation
- 1990-10-11 JP JP2514583A patent/JPH05501253A/ja active Pending
- 1990-10-11 DE DE69018084T patent/DE69018084T2/de not_active Expired - Fee Related
- 1990-10-11 ES ES90915604T patent/ES2069750T3/es not_active Expired - Lifetime
- 1990-10-11 EP EP90915604A patent/EP0495877B1/de not_active Expired - Lifetime
- 1990-10-11 DK DK90915604.4T patent/DK0495877T3/da active
- 1990-10-11 WO PCT/US1990/005838 patent/WO1991005797A1/en active IP Right Grant
- 1990-10-11 AU AU66050/90A patent/AU648520B2/en not_active Ceased
- 1990-10-11 AT AT90915604T patent/ATE120203T1/de not_active IP Right Cessation
- 1990-10-11 CA CA002067505A patent/CA2067505A1/en not_active Abandoned
-
1992
- 1992-04-10 NO NO92921454A patent/NO921454L/no unknown
- 1992-04-10 FI FI921609A patent/FI921609A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH05501253A (ja) | 1993-03-11 |
ATE120203T1 (de) | 1995-04-15 |
US5059588A (en) | 1991-10-22 |
NO921454L (no) | 1992-06-10 |
FI921609A (fi) | 1992-04-10 |
NO921454D0 (no) | 1992-04-10 |
EP0495877A1 (de) | 1992-07-29 |
FI921609A0 (fi) | 1992-04-10 |
AU648520B2 (en) | 1994-04-28 |
WO1991005797A1 (en) | 1991-05-02 |
AU6605090A (en) | 1991-05-16 |
CA2067505A1 (en) | 1991-04-14 |
DK0495877T3 (da) | 1995-08-21 |
DE69018084T2 (de) | 1995-07-27 |
KR927003079A (ko) | 1992-12-17 |
ES2069750T3 (es) | 1995-05-16 |
EP0495877B1 (de) | 1995-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |