DE69015919D1 - 4-(2-Methyl-2-hydrooxypropylamino)-5,6-dihydrothieno-(2,3-B)thiopyran-2-sulfonamid-7,7-dioxid. - Google Patents

4-(2-Methyl-2-hydrooxypropylamino)-5,6-dihydrothieno-(2,3-B)thiopyran-2-sulfonamid-7,7-dioxid.

Info

Publication number
DE69015919D1
DE69015919D1 DE69015919T DE69015919T DE69015919D1 DE 69015919 D1 DE69015919 D1 DE 69015919D1 DE 69015919 T DE69015919 T DE 69015919T DE 69015919 T DE69015919 T DE 69015919T DE 69015919 D1 DE69015919 D1 DE 69015919D1
Authority
DE
Germany
Prior art keywords
hydrooxypropylamino
dihydrothieno
thiopyran
sulfonamide
dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69015919T
Other languages
English (en)
Other versions
DE69015919T2 (de
Inventor
Jacob M Hoffman
Antony G Zacchei
Ling L Lee
Sandor L Varga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69015919D1 publication Critical patent/DE69015919D1/de
Publication of DE69015919T2 publication Critical patent/DE69015919T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69015919T 1989-07-31 1990-07-27 4-(2-Methyl-2-hydrooxypropylamino)-5,6-dihydrothieno-(2,3-B)thiopyran-2-sulfonamid-7,7-dioxid. Expired - Fee Related DE69015919T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,033 US4946859A (en) 1989-07-31 1989-07-31 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide

Publications (2)

Publication Number Publication Date
DE69015919D1 true DE69015919D1 (de) 1995-02-23
DE69015919T2 DE69015919T2 (de) 1995-06-08

Family

ID=23528160

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69015919T Expired - Fee Related DE69015919T2 (de) 1989-07-31 1990-07-27 4-(2-Methyl-2-hydrooxypropylamino)-5,6-dihydrothieno-(2,3-B)thiopyran-2-sulfonamid-7,7-dioxid.

Country Status (5)

Country Link
US (1) US4946859A (de)
EP (1) EP0411702B1 (de)
JP (1) JPH03141284A (de)
CA (1) CA2022118A1 (de)
DE (1) DE69015919T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120757A (en) * 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
US5157129A (en) * 1990-04-18 1992-10-20 Merck & Co., Inc. Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
ES2118941T3 (es) * 1992-02-21 1998-10-01 Alcon Lab Inc Composiciones antiglaucoma topicas que comprenden inhibidores de anhidrasa carbonica y bloqueantes beta.
CA2536185C (en) * 2003-08-20 2012-06-26 Santen Pharmaceutical Co., Ltd. Drug delivery system by administrating fine particles to sub-tenon
RU2414193C2 (ru) * 2005-07-29 2011-03-20 Сантен Фармасьютикал Ко., Лтд. Неинвазивная система доставки лекарственного средства к ткани заднего сегмента глаза с применением твердой композиции
US20090026101A1 (en) * 2007-07-24 2009-01-29 Hicks Zellestine C Disposable scented sanitary bag

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
US4677115A (en) * 1984-12-12 1987-06-30 Merck & Co., Inc. Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof
US4797413A (en) * 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4824968A (en) * 1984-12-12 1989-04-25 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
CA1320487C (en) * 1987-08-03 1993-07-20 George D. Hartman Substituted thieno[2,3-.beta.]thiophene-2-sulfonamides as antiglaucoma agents

Also Published As

Publication number Publication date
JPH03141284A (ja) 1991-06-17
EP0411702B1 (de) 1995-01-11
DE69015919T2 (de) 1995-06-08
US4946859A (en) 1990-08-07
CA2022118A1 (en) 1991-02-01
EP0411702A1 (de) 1991-02-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee