DE69007010T2 - Nichtfestes Augenarzneimittel und Verfahren zur Herstellung dieses Arzneimittels. - Google Patents

Nichtfestes Augenarzneimittel und Verfahren zur Herstellung dieses Arzneimittels.

Info

Publication number
DE69007010T2
DE69007010T2 DE69007010T DE69007010T DE69007010T2 DE 69007010 T2 DE69007010 T2 DE 69007010T2 DE 69007010 T DE69007010 T DE 69007010T DE 69007010 T DE69007010 T DE 69007010T DE 69007010 T2 DE69007010 T2 DE 69007010T2
Authority
DE
Germany
Prior art keywords
medicinal product
solid
manufacturing
dissolution
microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69007010T
Other languages
English (en)
Other versions
DE69007010D1 (de
Inventor
Annouk Rozier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Original Assignee
Laboratories Merck Sharp and Dohme Chibret SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Merck Sharp and Dohme Chibret SAS filed Critical Laboratories Merck Sharp and Dohme Chibret SAS
Publication of DE69007010D1 publication Critical patent/DE69007010D1/de
Application granted granted Critical
Publication of DE69007010T2 publication Critical patent/DE69007010T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69007010T 1989-10-17 1990-10-12 Nichtfestes Augenarzneimittel und Verfahren zur Herstellung dieses Arzneimittels. Expired - Fee Related DE69007010T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8913533A FR2653018A1 (fr) 1989-10-17 1989-10-17 Composition ophtalmique non solide a base de microparticules de polymere contenant au moins un principe actif en suspension dans un milieu dispersant et procede de preparation de ladite composition.

Publications (2)

Publication Number Publication Date
DE69007010D1 DE69007010D1 (de) 1994-04-07
DE69007010T2 true DE69007010T2 (de) 1994-08-04

Family

ID=9386462

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69007010T Expired - Fee Related DE69007010T2 (de) 1989-10-17 1990-10-12 Nichtfestes Augenarzneimittel und Verfahren zur Herstellung dieses Arzneimittels.

Country Status (9)

Country Link
EP (1) EP0424042B1 (de)
JP (1) JPH03206031A (de)
AT (1) ATE102025T1 (de)
CA (1) CA2027607A1 (de)
DE (1) DE69007010T2 (de)
DK (1) DK0424042T3 (de)
ES (1) ES2062401T3 (de)
FR (1) FR2653018A1 (de)
IE (1) IE64044B1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
EP0577034A3 (de) * 1992-06-30 1994-12-14 Senju Pharma Co Futterzusammensetzung für Fische und Schalentiere und Verfahren zur Verhinderung der Verschmutzung des für die Züchtung von Fischen und Schalentiere benötigten Wassers.
CA2101126A1 (en) * 1992-08-03 1994-02-04 Yasushi Morita Preparation for local treatment
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
CZ285636B6 (cs) * 1995-02-07 1999-10-13 Ústav Makromolekulární Chemie Av Čr Nové lékové formy pro farmaka aplikovaná v očním lékařství s prolongovanou účinností a způsob jejich výroby
KR20030079990A (ko) * 2001-02-15 2003-10-10 가부시키가이샤산와카가쿠켄큐쇼 신규 안과용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions

Also Published As

Publication number Publication date
ES2062401T3 (es) 1994-12-16
DE69007010D1 (de) 1994-04-07
EP0424042B1 (de) 1994-03-02
DK0424042T3 (da) 1994-03-28
EP0424042A1 (de) 1991-04-24
ATE102025T1 (de) 1994-03-15
FR2653018A1 (fr) 1991-04-19
IE64044B1 (en) 1995-06-28
CA2027607A1 (en) 1991-04-18
JPH03206031A (ja) 1991-09-09
IE903712A1 (en) 1991-04-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LABORATOIRES MERCK SHARP & DOHME-CHIBRET SNC, PARI

8339 Ceased/non-payment of the annual fee