DE69004455D1 - Alpha-adrenergene Rezeptor-Antagonisten. - Google Patents

Alpha-adrenergene Rezeptor-Antagonisten.

Info

Publication number
DE69004455D1
DE69004455D1 DE90301741T DE69004455T DE69004455D1 DE 69004455 D1 DE69004455 D1 DE 69004455D1 DE 90301741 T DE90301741 T DE 90301741T DE 69004455 T DE69004455 T DE 69004455T DE 69004455 D1 DE69004455 D1 DE 69004455D1
Authority
DE
Germany
Prior art keywords
receptor antagonists
adrenergic receptor
alpha adrenergic
alpha
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90301741T
Other languages
English (en)
Other versions
DE69004455T2 (de
Inventor
Thomas Wen-Fu Ku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
SmithKline Beecham Corp
Original Assignee
GlaxoSmithKline LLC
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline LLC, SmithKline Beecham Corp filed Critical GlaxoSmithKline LLC
Application granted granted Critical
Publication of DE69004455D1 publication Critical patent/DE69004455D1/de
Publication of DE69004455T2 publication Critical patent/DE69004455T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE90301741T 1989-02-23 1990-02-19 Alpha-adrenergene Rezeptor-Antagonisten. Expired - Fee Related DE69004455T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/315,370 US4981849A (en) 1989-02-23 1989-02-23 Alpha-adrenergic receptor antagonists

Publications (2)

Publication Number Publication Date
DE69004455D1 true DE69004455D1 (de) 1993-12-16
DE69004455T2 DE69004455T2 (de) 1994-03-10

Family

ID=23224088

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90301741T Expired - Fee Related DE69004455T2 (de) 1989-02-23 1990-02-19 Alpha-adrenergene Rezeptor-Antagonisten.

Country Status (4)

Country Link
US (1) US4981849A (de)
EP (1) EP0384676B1 (de)
JP (1) JPH02240085A (de)
DE (1) DE69004455T2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5458883A (en) * 1994-01-12 1995-10-17 Duke University Method of treating disorders of the eye
US20090253654A1 (en) 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
EP1777222A1 (de) 2005-09-22 2007-04-25 Galantos Pharma GmbH Cholinesterase Inhibitoren mit erhöter Blut Hirn Schranke Permeabilität zur Behandlung von kognitiven Störungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3906000A (en) * 1972-02-23 1975-09-16 Pfizer Tricyclicazaindole derivatives
US3904645A (en) * 1972-02-23 1975-09-09 Pfizer Tricyclicazaindole derivatives
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
JPS5630176A (en) * 1979-08-22 1981-03-26 Hitachi Ltd Character generator
US4469634A (en) * 1982-07-29 1984-09-04 Smithkline Beckman Corporation Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines
ATE34392T1 (de) * 1983-10-17 1988-06-15 Synthelabo Imidazolinderivate, ihre herstellung und therapeutische verwendung.
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4769368A (en) * 1986-02-10 1988-09-06 Smithkline Beckman Corporation 2,3,4,8,9,9A-Hexahydro-4-aryl-1H-indeno(1,7-CD)azepines

Also Published As

Publication number Publication date
US4981849A (en) 1991-01-01
EP0384676B1 (de) 1993-11-10
DE69004455T2 (de) 1994-03-10
JPH02240085A (ja) 1990-09-25
EP0384676A1 (de) 1990-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee