DE68918440D1 - Verfahren zur transformation von menschlichen b-lymphocyten. - Google Patents

Verfahren zur transformation von menschlichen b-lymphocyten.

Info

Publication number
DE68918440D1
DE68918440D1 DE68918440T DE68918440T DE68918440D1 DE 68918440 D1 DE68918440 D1 DE 68918440D1 DE 68918440 T DE68918440 T DE 68918440T DE 68918440 T DE68918440 T DE 68918440T DE 68918440 D1 DE68918440 D1 DE 68918440D1
Authority
DE
Germany
Prior art keywords
cells
transforming
lymphocytes
human
epstein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68918440T
Other languages
English (en)
Other versions
DE68918440T2 (de
Inventor
Riccardo Dalla-Favera
Stephanie Seremitis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University NYU filed Critical New York University NYU
Publication of DE68918440D1 publication Critical patent/DE68918440D1/de
Application granted granted Critical
Publication of DE68918440T2 publication Critical patent/DE68918440T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE68918440T 1988-12-19 1989-12-15 Verfahren zur transformation von menschlichen b-lymphocyten. Expired - Fee Related DE68918440T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28668088A 1988-12-19 1988-12-19
US34093989A 1989-04-20 1989-04-20
PCT/US1989/005885 WO1990006994A1 (en) 1988-12-19 1989-12-15 Method for transforming human b lymphocytes

Publications (2)

Publication Number Publication Date
DE68918440D1 true DE68918440D1 (de) 1994-10-27
DE68918440T2 DE68918440T2 (de) 1995-01-19

Family

ID=26964003

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68918440T Expired - Fee Related DE68918440T2 (de) 1988-12-19 1989-12-15 Verfahren zur transformation von menschlichen b-lymphocyten.

Country Status (6)

Country Link
EP (1) EP0404925B1 (de)
JP (1) JPH03503960A (de)
AT (1) ATE111954T1 (de)
CA (1) CA2005744A1 (de)
DE (1) DE68918440T2 (de)
WO (1) WO1990006994A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2398783A (en) 2003-02-26 2004-09-01 Antonio Lanzavecchia A method for producing immortalised human B memory lymphocytes
EP1615956A1 (de) * 2003-04-14 2006-01-18 Board Of Regents The University Of Texas System Verfahren zur ex-vivo, hybridomfreien, produktion von poly- und monoklonalen antikörpern und herstellung von immortalisierten zellpopulationen
WO2007060864A1 (ja) * 2005-11-24 2007-05-31 National University Corporation NARA Institute of Science and Technology 増殖と分化の制御可能な抗体産生前駆ｂ細胞

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652522A (en) * 1983-07-05 1987-03-24 The University Of Pennsylvania Continuous lymphocyte cell lines, their production and use
US4804627A (en) * 1985-05-09 1989-02-14 Sloan-Kettering Institute For Cancer Research Method for cloning lymphoblastoid cells

Also Published As

Publication number Publication date
CA2005744A1 (en) 1990-06-19
JPH03503960A (ja) 1991-09-05
DE68918440T2 (de) 1995-01-19
EP0404925A4 (en) 1992-07-08
WO1990006994A1 (en) 1990-06-28
EP0404925B1 (de) 1994-09-21
EP0404925A1 (de) 1991-01-02
ATE111954T1 (de) 1994-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee