DE68915097D1 - Apovincaminsäure-Derivate. - Google Patents
Apovincaminsäure-Derivate.Info
- Publication number
- DE68915097D1 DE68915097D1 DE68915097T DE68915097T DE68915097D1 DE 68915097 D1 DE68915097 D1 DE 68915097D1 DE 68915097 T DE68915097 T DE 68915097T DE 68915097 T DE68915097 T DE 68915097T DE 68915097 D1 DE68915097 D1 DE 68915097D1
- Authority
- DE
- Germany
- Prior art keywords
- acid derivatives
- apovincamic acid
- injuries
- apovincamic
- hypertension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002253 acid Substances 0.000 title 1
- 230000006378 damage Effects 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- ZFCQLDAGNBFMJQ-QUCCMNQESA-N apovincaminic acid Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(O)=O)N5C2=C1 ZFCQLDAGNBFMJQ-QUCCMNQESA-N 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24688488 | 1988-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68915097D1 true DE68915097D1 (de) | 1994-06-09 |
DE68915097T2 DE68915097T2 (de) | 1994-08-25 |
Family
ID=17155177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68915097T Expired - Fee Related DE68915097T2 (de) | 1988-09-30 | 1989-09-27 | Apovincaminsäure-Derivate. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4980474A (de) |
EP (1) | EP0361888B1 (de) |
JP (1) | JPH02167279A (de) |
KR (1) | KR0126674B1 (de) |
AT (1) | ATE105289T1 (de) |
CA (1) | CA1333394C (de) |
DE (1) | DE68915097T2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0672413A1 (de) * | 1991-12-10 | 1995-09-20 | Taisho Pharmaceutical Co. Ltd | Neue verwendung von (+)-2-nitroxyethyl-apovincaminat |
HUT72416A (en) * | 1993-03-15 | 1996-04-29 | Byk Nederland Bv | Substituted alkyl-nitrates and their use to prepare pharmaceuticals for the treatment of pathologically increased intraocular pressure |
WO1996025161A1 (en) * | 1995-02-15 | 1996-08-22 | Takeda Chemical Industries, Ltd. | Use of vinpocetine derivatives for inhibiting production or secretion of amyloid beta protein |
GB2467661B (en) | 2007-09-20 | 2013-02-13 | Bradley Fixtures Corp | Lavatory system |
WO2011044247A1 (en) | 2009-10-07 | 2011-04-14 | Bradley Fixtures Corporation | Lavatory system with hand dryer |
US9267736B2 (en) | 2011-04-18 | 2016-02-23 | Bradley Fixtures Corporation | Hand dryer with point of ingress dependent air delay and filter sensor |
US9170148B2 (en) | 2011-04-18 | 2015-10-27 | Bradley Fixtures Corporation | Soap dispenser having fluid level sensor |
EP2828440B1 (de) | 2012-03-21 | 2018-06-27 | Bradley Fixtures Corporation | Becken und handtrocknungssystem |
US10100501B2 (en) | 2012-08-24 | 2018-10-16 | Bradley Fixtures Corporation | Multi-purpose hand washing station |
US11015329B2 (en) | 2016-06-08 | 2021-05-25 | Bradley Corporation | Lavatory drain system |
US10041236B2 (en) | 2016-06-08 | 2018-08-07 | Bradley Corporation | Multi-function fixture for a lavatory system |
CN114920743B (zh) * | 2022-05-09 | 2023-08-04 | 南京中医药大学 | 一种吲哚生物碱及其制备方法与应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2228479B1 (de) * | 1973-05-07 | 1976-05-14 | Synthelabo | |
IT1148733B (it) * | 1980-11-14 | 1986-12-03 | Medea Res Srl | Derivati della vincamina,metodo per la sua preparazione e composizione farmaceutiche che lo contengono |
HU187733B (en) * | 1982-06-30 | 1986-02-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing apovincaminic acid derivatives |
DK311683A (da) * | 1982-07-26 | 1984-01-27 | Fujisawa Pharmaceutical Co | Fremgangsmaade til fremstilling af pyridylalkylnitratforbindelser |
HU198207B (en) * | 1985-04-19 | 1989-08-28 | Richter Gedeon Vegyeszet | Process for production of derivatives of eburnamenin and medical compositions containing them |
-
1989
- 1989-08-22 JP JP1215571A patent/JPH02167279A/ja active Granted
- 1989-09-12 US US07/405,972 patent/US4980474A/en not_active Expired - Fee Related
- 1989-09-15 CA CA000611590A patent/CA1333394C/en not_active Expired - Fee Related
- 1989-09-27 DE DE68915097T patent/DE68915097T2/de not_active Expired - Fee Related
- 1989-09-27 EP EP89309829A patent/EP0361888B1/de not_active Expired - Lifetime
- 1989-09-27 AT AT8989309829T patent/ATE105289T1/de not_active IP Right Cessation
- 1989-09-29 KR KR1019890014015A patent/KR0126674B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE105289T1 (de) | 1994-05-15 |
DE68915097T2 (de) | 1994-08-25 |
EP0361888B1 (de) | 1994-05-04 |
JPH02167279A (ja) | 1990-06-27 |
CA1333394C (en) | 1994-12-06 |
EP0361888A3 (de) | 1991-01-02 |
KR0126674B1 (ko) | 1998-04-01 |
KR900004731A (ko) | 1990-04-12 |
JPH0549673B2 (de) | 1993-07-26 |
EP0361888A2 (de) | 1990-04-04 |
US4980474A (en) | 1990-12-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |