DE68915070T2 - Zellkultur-Reaktor. - Google Patents

Zellkultur-Reaktor.

Info

Publication number
DE68915070T2
DE68915070T2 DE68915070T DE68915070T DE68915070T2 DE 68915070 T2 DE68915070 T2 DE 68915070T2 DE 68915070 T DE68915070 T DE 68915070T DE 68915070 T DE68915070 T DE 68915070T DE 68915070 T2 DE68915070 T2 DE 68915070T2
Authority
DE
Germany
Prior art keywords
cell culture
culture reactor
reactor
cell
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68915070T
Other languages
English (en)
Other versions
DE68915070D1 (de
Inventor
David W Armstrong
L Perry Fleming
Deborah G Grenzowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
National Research Council of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada filed Critical National Research Council of Canada
Application granted granted Critical
Publication of DE68915070D1 publication Critical patent/DE68915070D1/de
Publication of DE68915070T2 publication Critical patent/DE68915070T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
DE68915070T 1988-07-19 1989-07-14 Zellkultur-Reaktor. Expired - Fee Related DE68915070T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000573901A CA1307225C (en) 1988-07-19 1988-07-19 Cell culture bioreactor

Publications (2)

Publication Number Publication Date
DE68915070D1 DE68915070D1 (de) 1994-06-09
DE68915070T2 true DE68915070T2 (de) 1994-12-01

Family

ID=4138494

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68915070T Expired - Fee Related DE68915070T2 (de) 1988-07-19 1989-07-14 Zellkultur-Reaktor.

Country Status (5)

Country Link
US (1) US4906577A (de)
EP (1) EP0353893B1 (de)
JP (1) JPH0276569A (de)
CA (1) CA1307225C (de)
DE (1) DE68915070T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3942014A4 (de) * 2019-04-22 2023-01-18 Lonza Ltd. Kontinuierliches schaufelrad

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US5252220A (en) * 1989-09-25 1993-10-12 Symbiotech Incorporated Preparation of analytical samples by liquid-liquid extraction using microporous hollow-fiber membranes
US5248613A (en) * 1991-07-08 1993-09-28 Roubicek Rudolf V Nonhomogeneous centrifugal film bioreactor
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
JP3246664B2 (ja) * 1993-01-29 2002-01-15 ニュー ブルンズウイック サイエンティフィック カンパニー インコーポレイテッド 足場および懸濁細胞の培養方法並びにその装置
US5342781A (en) * 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor
US5443985A (en) * 1993-07-22 1995-08-22 Alberta Research Council Cell culture bioreactor
US5512480A (en) * 1994-03-11 1996-04-30 Baxter International Inc. Flow-through bioreactor with grooves for cell retention
US5700087A (en) * 1995-10-06 1997-12-23 Beckett; Arnold H. Device maximizing dispersion of aggregate in liquid diluent
US6087155A (en) * 1998-01-14 2000-07-11 York; Billy G. On site microbial bioremediation system and method of using said system
US6001642A (en) * 1998-06-29 1999-12-14 Wyle Laboratories, Inc. Life Sciences Bioreactor and cell culturing processes using the bioreactor
US5972661A (en) 1998-09-28 1999-10-26 Penn State Research Foundation Mixing systems
EP1468289A4 (de) * 2001-10-26 2007-07-04 Millipore Corp Assaysysteme mit einstellbarer fluidkommunikation
US20080187949A1 (en) * 2001-10-26 2008-08-07 Millipore Corporation Multiplexed assays of cell migration
US20040126773A1 (en) * 2002-05-23 2004-07-01 Beske Oren E. Assays with coded sensor particles to sense assay conditions
US20080207465A1 (en) * 2002-10-28 2008-08-28 Millipore Corporation Assay systems with adjustable fluid communication
US7175118B2 (en) * 2003-01-31 2007-02-13 Hockmeyer Equipment Corp. Apparatus and method for processing high viscosity dispersions
US20090137018A1 (en) 2003-06-30 2009-05-28 University Of South Florida Magnetic three-dimensional cell culture apparatus and method
WO2005010139A2 (en) 2003-07-23 2005-02-03 University Of South Florida Ferromagnetic cell and tissue culture microcarriers
GB0318411D0 (en) * 2003-08-06 2003-09-10 Univ Hull Vessel
EP1687400A4 (de) 2003-10-08 2009-01-07 Wolf Wilson Mfg Corp Zellkulturverfahren und vorrichtungen mit nutzung gasdurchlässiger materialien
AU2004229070A1 (en) * 2003-11-13 2005-06-02 Dale C. Gyure Novel bioreactor
US20080020049A1 (en) * 2005-02-25 2008-01-24 Andrew Darling Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications
US7840272B2 (en) 2005-06-03 2010-11-23 Medrelief Inc. Methods for modulating osteochondral development using bioelectrical stimulation
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
WO2007025145A2 (en) * 2005-08-25 2007-03-01 Solix Biofuels, Inc. Method, apparatus and system for biodiesel production from algae
US7749761B2 (en) * 2005-09-29 2010-07-06 Industrial Technology Research Institute Hydrogel composition for cell culture apparatus
AU2007332869B2 (en) * 2006-12-07 2012-10-11 Wilson Wolf Manufacturing, LLC Highly efficient gas permeable devices and methods for culturing cells
NZ587206A (en) * 2008-01-31 2012-01-12 Ecoduna Og A photochemical process for cultivation of microorganisms in a bioreactor
US20090199904A1 (en) * 2008-02-13 2009-08-13 Babbitt Guy R Low shear pumps for use with bioreactors
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
JP5395171B2 (ja) * 2008-07-08 2014-01-22 ウィルソン ウォルフ マニュファクチャリング コーポレイション 気体透過性の細胞培養装置および使用方法
EP2318509A2 (de) * 2008-08-01 2011-05-11 Smart Biosystems APS Probeneinlass eines zellkultursystems
US9862923B2 (en) 2010-03-26 2018-01-09 Philip Morris Usa Inc. Cultured tobacco cells as a matrix for consumable products
KR101408800B1 (ko) * 2012-05-10 2014-06-19 서강대학교산학협력단 다중 격벽 구조를 갖는 광생물반응기
US10617070B2 (en) 2014-10-06 2020-04-14 Life Technologies Corporation Methods and systems for culturing microbial and cellular seed cultures
EP3207119B1 (de) 2014-10-17 2020-02-19 Sani-tech West, Inc. Misch- und filterungssystem
US10071350B2 (en) 2015-04-07 2018-09-11 President And Fellows Of Harvard College Microfluidic active mixing nozzle for three-dimensional printing of viscoelastic inks
PL227303B1 (pl) 2015-04-30 2017-11-30 Zachodniopomorski Univ Technologiczny W Szczecinie Dwukomorowy reaktor do magnetycznego wspomagania procesów chemicznych i układ z tym reaktorem
US10385364B1 (en) * 2016-07-01 2019-08-20 Mark K Gaalswyk Cellulose liquefaction module
CN108893253B (zh) * 2018-07-27 2021-11-12 吉林大学珠海学院 一种生物发酵装置
CN109294888B (zh) * 2018-08-31 2021-12-03 广东叶氏药业有限公司 益生菌发酵饮品制备装置、组分配比及其工艺方法
WO2021251312A1 (ja) * 2020-06-08 2021-12-16 国立大学法人 東京医科歯科大学 細胞培養方法
CN111662826B (zh) * 2020-06-23 2023-07-28 肇庆大华农生物药品有限公司 一种高密度大规模细胞培养的生物反应器

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US2244902A (en) * 1937-12-23 1941-06-10 Stich Eugen Process for the automatic cultivation of yeast
SU414298A1 (de) * 1971-04-06 1974-02-05
CH651587A5 (de) * 1980-11-18 1985-09-30 Chemap Ag Verfahren und vorrichtung zur submersen zuechtung von zellkulturen.
CH663422A5 (de) * 1982-05-27 1987-12-15 Chemap Ag Verfahren und fermenter zur zuechtung von gewebezellen.
US4764471A (en) * 1984-01-04 1988-08-16 Nabisco Brands, Inc. Continuous bioreactor and process
US4668632A (en) * 1985-02-06 1987-05-26 Vxr, Inc. Sparger and apparatus for and method of growing cells
WO1986005202A1 (en) * 1985-02-28 1986-09-12 Verax Corporation Fluidized bioreactor and cell cultivation process
DE3544382A1 (de) * 1985-12-14 1987-06-19 Ivan Prof Dr Ing Sekoulov Verfahren zur sauerstoffversorgung von bioreaktoren und vorrichtung zur durchfuehrung des verfahrens und die anwendung der vorrichtung
DE3612453A1 (de) * 1986-04-14 1987-10-15 Diessel Gmbh & Co Vorrichtung zur kultivierung von zellkulturen
DE3625698A1 (de) * 1986-07-30 1988-02-18 Hoechst Ag Sterilisierbarer wirbelschichtfermenter

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3942014A4 (de) * 2019-04-22 2023-01-18 Lonza Ltd. Kontinuierliches schaufelrad

Also Published As

Publication number Publication date
EP0353893A2 (de) 1990-02-07
DE68915070D1 (de) 1994-06-09
JPH0276569A (ja) 1990-03-15
EP0353893A3 (en) 1990-03-07
CA1307225C (en) 1992-09-08
EP0353893B1 (de) 1994-05-04
US4906577A (en) 1990-03-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee