DE68912477D1 - Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzien zu dessen messung. - Google Patents

Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzien zu dessen messung.

Info

Publication number
DE68912477D1
DE68912477D1 DE89902805T DE68912477T DE68912477D1 DE 68912477 D1 DE68912477 D1 DE 68912477D1 DE 89902805 T DE89902805 T DE 89902805T DE 68912477 T DE68912477 T DE 68912477T DE 68912477 D1 DE68912477 D1 DE 68912477D1
Authority
DE
Germany
Prior art keywords
measuring
reagents
biological effect
antithrombin iii
antithrombin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89902805T
Other languages
English (en)
Other versions
DE68912477T3 (de
DE68912477T2 (de
Inventor
Masayasu Enomoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shoji Co Ltd
Original Assignee
Nippon Shoji Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12910808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68912477(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Shoji Co Ltd filed Critical Nippon Shoji Co Ltd
Application granted granted Critical
Publication of DE68912477D1 publication Critical patent/DE68912477D1/de
Publication of DE68912477T2 publication Critical patent/DE68912477T2/de
Publication of DE68912477T3 publication Critical patent/DE68912477T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE68912477T 1988-03-03 1989-02-22 Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzkit zu dessen messung Expired - Fee Related DE68912477T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5229588 1988-03-03
PCT/JP1989/000173 WO1989008150A1 (en) 1988-03-03 1989-02-22 Method for measuring biological activity of antithrombin iii and reagents for the measurement

Publications (3)

Publication Number Publication Date
DE68912477D1 true DE68912477D1 (de) 1994-03-03
DE68912477T2 DE68912477T2 (de) 1994-06-30
DE68912477T3 DE68912477T3 (de) 1999-12-23

Family

ID=12910808

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68912477T Expired - Fee Related DE68912477T3 (de) 1988-03-03 1989-02-22 Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzkit zu dessen messung

Country Status (5)

Country Link
US (1) US5093237A (de)
EP (1) EP0360871B2 (de)
DE (1) DE68912477T3 (de)
FI (1) FI895215A0 (de)
WO (1) WO1989008150A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221614A (en) * 1988-03-03 1993-06-22 Nippon Shoji Kabushiki Kaisha Method and reagent for determining the biological activity of antithrombin III by measuring coagulation time
DE4133946A1 (de) * 1991-10-14 1993-04-15 Behringwerke Ag Funktioneller test und reagenz zur bestimmung von fibrinogen
KR100305306B1 (ko) * 1993-02-17 2001-11-22 존 펑크하우저 건식화학캐스케이드면역분석법및친화도분석법
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
JPH078298A (ja) * 1993-06-28 1995-01-13 Nippon Shoji Kk アンチトロンビンｉｉｉ活性の測定方法および該測定用試薬キット
EP0716744B1 (de) * 1994-06-30 2001-11-07 Dade Behring Inc. Bioaktive poröse trennteile
DE19538716A1 (de) * 1995-10-18 1997-04-24 Behringwerke Ag Verfahren zur Quantifizierung von aktiviertem Gerinnungsfaktor VII (FVIIa)
DE19538715A1 (de) 1995-10-18 1997-04-30 Behringwerke Ag Verfahren zur Reinigung von Faktor VII und aktiviertem Faktor VII
US5958716A (en) * 1996-06-06 1999-09-28 Dade Behring Inc. Blood factor assay
US5985582A (en) * 1997-12-09 1999-11-16 Sigma-Aldrich Co. Thrombin-based assay for antithrombin III
US6432658B1 (en) 2000-09-13 2002-08-13 Affinity Biologicals, Inc. Method for measuring antithrombin activity
EP1918718A1 (de) * 2006-10-31 2008-05-07 Roche Diagnostics GmbH Verfahren und Vorrichtungen zur elektrochemischen Bestimmung von Faktor Xa-Inhibitoren in Blutproben

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1043913B (it) * 1973-04-02 1980-02-29 Behringwerke Ag Tromboplastina parziale suo impiego come diagnostico e processo per la sua prparazione
DE3005540A1 (de) * 1980-02-14 1981-08-20 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagens zur bestimmung der biologischen aktivitaet von heparin im plasma
JPS57102650A (en) * 1980-12-19 1982-06-25 Ricoh Co Ltd Electrophotographic receptor
JPS58220697A (ja) * 1982-06-15 1983-12-22 Green Cross Corp:The アンテイトロンビン−３の活性測定方法及びその方法を使用するキツト
DE3413311A1 (de) * 1984-04-09 1985-10-17 Behringwerke Ag, 3550 Marburg Reagenz zur bestimmung der thromboplastinzeit
US4948724A (en) * 1985-09-05 1990-08-14 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
ATE64470T1 (de) * 1985-09-05 1991-06-15 E Thye Yin Verfahren und zusammensetzungen zur bestimmung von heparin.
JPS62159048A (ja) * 1986-01-03 1987-07-15 Eiken Kagaku Kk プロテインｓの生物活性測定法
JPH0442154Y2 (de) * 1986-01-04 1992-10-05

Also Published As

Publication number Publication date
US5093237A (en) 1992-03-03
WO1989008150A1 (en) 1989-09-08
DE68912477T3 (de) 1999-12-23
DE68912477T2 (de) 1994-06-30
EP0360871A1 (de) 1990-04-04
EP0360871B2 (de) 1999-06-30
EP0360871A4 (en) 1990-10-24
FI895215A0 (fi) 1989-11-02
EP0360871B1 (de) 1994-01-19

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee