DE667921C - Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment - Google Patents

Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment

Info

Publication number
DE667921C
DE667921C DEC50755D DEC0050755D DE667921C DE 667921 C DE667921 C DE 667921C DE C50755 D DEC50755 D DE C50755D DE C0050755 D DEC0050755 D DE C0050755D DE 667921 C DE667921 C DE 667921C
Authority
DE
Germany
Prior art keywords
porous carrier
similar substances
internal treatment
substances used
pancreatic gland
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEC50755D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DEC50755D priority Critical patent/DE667921C/en
Priority to CH205677D priority patent/CH205677A/en
Priority to FR835825D priority patent/FR835825A/en
Application granted granted Critical
Publication of DE667921C publication Critical patent/DE667921C/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2873Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Description

Es ist bekannt, flüssige Nährstoffe, Chemikalien u. dgl. in feste, im Darm unveränderlich bleibende poröse Körper, z. B. Kleie, Holzkörner, Holzkohle-, Glas- oder Quarzsandkugeln oder gebrannte Tonkugeln hineinzupressen und diese Körper nach Bedarf mit einer im Darm sich auflösenden Schutzhülle zu überziehen.It is known to convert liquid nutrients, chemicals and the like into solid ones that are immutable in the intestine permanent porous bodies, e.g. B. bran, wood grains, charcoal, glass or quartz sand balls or to press burnt clay balls into it and cover these bodies with a protective covering that dissolves in the intestine as required to cover.

Versuche haben ergeben, daß derartige poröse Körper keinesfalls eine solche Beschaffenheit besitzen, daß sie nach dem Aufladen mit dem konzentrierten reinen Sekret der Pankreasdrüse und darauf erfolgenden Versehen mit einer Schutzhülle etwa derart unverändert erhalten werden, daß der poröse Jnnenkörper von dem flüssigen Sekret nicht zerstört wird.Experiments have shown that such porous bodies in no way have such a quality own that they take place after being charged with the concentrated pure secretion of the pancreatic gland and on it Provided with a protective cover about such a way unchanged that the porous The inner body is not destroyed by the liquid secretion.

Poröse Körper aus Quarzsand können indessen als Träger für das genannte Sekret zur inneren Behandlung nutzbar gemacht werden, wenn dem Rohkörper gemäß der Erfindung andere Bestandteile zugesetzt werden und diesem alsdann durch Glühen mit einem erheblich höheren Hitzegrade, als dies bisher möglich war, eine hohe Festigkeit verbunden mit einer hochgradigen, schwammartigen Porosität erteilt wird.Porous bodies made of quartz sand can, however, be used as a carrier for the said secretion can be used for internal treatment if the raw body according to the invention other constituents are added and this then by annealing with a significantly higher degree of heat than before was possible, a high strength combined with a high grade, spongy Porosity is granted.

Erfindungsgemäß werden zur Herstellung -des Trägers der in bekannter Weise aus Quarzsand bestehenden Rohmasse bei einem Gewicht von 125 g etwa 30 g Wasserglas und 5 g Kaolin beigemischt. Die nach Trocknung dieser Masse daraus gepreßten Kugeln werden nach völliger Trocknung z. B. in einem Tiegel- oder Muffelofen mit einem Hitzegrad von etwa 1150° geglüht. Zufolge des starken Glühens erhalten die Kugeln eine hohe Festigkeit, verbunden mit einer hochgradigen, gewissermaßen schwammartigen Porosität. Das alsdann in diesem hochporösen Träger aufgeladene Sekret ist nicht imstande, nach dem in bekannter Weise er-' folgenden Versehen der Träger (Kugeln) mit einem Wachs- und Keratinüberzug, darauf erfolgendem Abkühl·η und Dragieren, diese besonders gearteten Träger irgendwie zerstörend anzugre.fen. Es wird vielmehr bis zur im Dann erfolgenden Auflösung des Überzugs des Trägers in diesem ohne Mengeneinbuße flüssig erhalten, um erst dann zur vollen $0 Einwirkung zu gelangen.According to the invention, about 30 g of water glass and 5 g of kaolin are admixed with the raw material consisting of quartz sand in a known manner and weighing 125 g to produce the carrier. The balls pressed therefrom after drying this mass are, after complete drying, z. B. annealed in a crucible or muffle furnace with a heat level of about 1150 °. As a result of the intense annealing, the balls acquire a high degree of strength, combined with a high-grade, to a certain extent spongy, porosity. The secretion then charged in this highly porous carrier is not able, after the carrier (balls) has been provided in a known manner with a wax and keratin coating, followed by cooling and coating, to destroy these special carriers in any way. fen. Rather, it is to receive liquid to the Dann taking place dissolution of the coating of the carrier in this amount without penalty to go until the full $ 0 exposure.

Claims (1)

Patentanspruch:Claim: Poröser Träger für zur inneren- Behandlung dienende konzentrierte reine Sekrete der Pankreasdrüse und ähnliche Stoffe, dadurch gekennzeichnet, daß man aus Quarzsand unter Zumischen von Wasserglas und Kaolin Kugeln formt und diese nach dem Trocknen bei etwa 1150° glüht.Porous carrier for concentrated pure secretions used for internal treatment the pancreatic gland and similar substances, characterized in that one from quartz sand by adding water glass and kaolin to form balls and these after drying, it glows at about 1150 °.
DEC50755D 1935-07-24 1935-07-24 Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment Expired DE667921C (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DEC50755D DE667921C (en) 1935-07-24 1935-07-24 Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment
CH205677D CH205677A (en) 1935-07-24 1938-02-23 Process for making porous supports.
FR835825D FR835825A (en) 1935-07-24 1938-03-28 Porous support intended to receive in particular concentrated food substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEC50755D DE667921C (en) 1935-07-24 1935-07-24 Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment

Publications (1)

Publication Number Publication Date
DE667921C true DE667921C (en) 1941-12-04

Family

ID=7027240

Family Applications (1)

Application Number Title Priority Date Filing Date
DEC50755D Expired DE667921C (en) 1935-07-24 1935-07-24 Porous carrier for concentrated secretions of the pancreatic gland and similar substances used for internal treatment

Country Status (3)

Country Link
CH (1) CH205677A (en)
DE (1) DE667921C (en)
FR (1) FR835825A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE960922C (en) * 1952-07-24 1957-03-28 Fritz Neuwald Dr Process for the production of stable mixtures of inherently incompatible drugs
DE1164813B (en) * 1956-11-05 1964-03-05 Commw Scient Ind Res Org Process for the production of molded bodies, in particular pellets, for administration to ruminants

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE960922C (en) * 1952-07-24 1957-03-28 Fritz Neuwald Dr Process for the production of stable mixtures of inherently incompatible drugs
DE1164813B (en) * 1956-11-05 1964-03-05 Commw Scient Ind Res Org Process for the production of molded bodies, in particular pellets, for administration to ruminants

Also Published As

Publication number Publication date
CH205677A (en) 1939-06-30
FR835825A (en) 1939-01-04

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