DE6227T1 - - Google Patents

Info

Publication number

DE6227T1

DE6227T1 DE1979101934 DE79101934T DE6227T1 DE 6227 T1 DE6227 T1 DE 6227T1 DE 1979101934 DE1979101934 DE 1979101934 DE 79101934 T DE79101934 T DE 79101934T DE 6227 T1 DE6227 T1 DE 6227T1

Authority

DE

Germany

Prior art keywords

group

formula

namely

chain

dithiobis

Prior art date

1978-06-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 239000003814 drug Substances 0.000 claims 27
• -1 cyclohexylamino group Chemical group 0.000 claims 25
• 150000001875 compounds Chemical class 0.000 claims 16
• 125000004432 carbon atom Chemical group C* 0.000 claims 14
• 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims 10
• VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 6
• 239000005977 Ethylene Substances 0.000 claims 6
• 125000000217 alkyl group Chemical group 0.000 claims 6
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
• KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims 4
• 125000002947 alkylene group Chemical group 0.000 claims 4
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
• 125000003277 amino group Chemical group 0.000 claims 3
• SDNJNDFHCODQDQ-UHFFFAOYSA-N n-(2-ethylphenyl)-2-[[2-[(2-ethylphenyl)carbamoyl]phenyl]disulfanyl]benzamide Chemical compound CCC1=CC=CC=C1NC(=O)C1=CC=CC=C1SSC1=CC=CC=C1C(=O)NC1=CC=CC=C1CC SDNJNDFHCODQDQ-UHFFFAOYSA-N 0.000 claims 3
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
• 125000001424 substituent group Chemical group 0.000 claims 3
• YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Natural products C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims 2
• 239000004480 active ingredient Substances 0.000 claims 2
• 125000003545 alkoxy group Chemical group 0.000 claims 2
• 125000001691 aryl alkyl amino group Chemical group 0.000 claims 2
• 229910052801 chlorine Inorganic materials 0.000 claims 2
• 125000001309 chloro group Chemical group Cl* 0.000 claims 2
• 125000004093 cyano group Chemical group *C#N 0.000 claims 2
• 125000004663 dialkyl amino group Chemical group 0.000 claims 2
• 125000004986 diarylamino group Chemical group 0.000 claims 2
• 125000005843 halogen group Chemical group 0.000 claims 2
• 125000005191 hydroxyalkylamino group Chemical group 0.000 claims 2
• NQKAXKSLWJHSEC-UHFFFAOYSA-N n-(3-morpholin-4-ylpropyl)-2-[[2-(3-morpholin-4-ylpropylcarbamoyl)phenyl]disulfanyl]benzamide Chemical compound C=1C=CC=C(SSC=2C(=CC=CC=2)C(=O)NCCCN2CCOCC2)C=1C(=O)NCCCN1CCOCC1 NQKAXKSLWJHSEC-UHFFFAOYSA-N 0.000 claims 2
• 150000003839 salts Chemical class 0.000 claims 2
• ZMPGQRAMAKWWIJ-UHFFFAOYSA-N 2-(2,2-dimethoxyethyl)benzamide Chemical compound COC(CC1=C(C(=O)N)C=CC=C1)OC ZMPGQRAMAKWWIJ-UHFFFAOYSA-N 0.000 claims 1
• 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
• OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
• 101710095395 Histidine decarboxylase proenzyme Proteins 0.000 claims 1
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
• 125000003282 alkyl amino group Chemical group 0.000 claims 1
• 230000002785 anti-thrombosis Effects 0.000 claims 1
• 239000003146 anticoagulant agent Substances 0.000 claims 1
• 125000003710 aryl alkyl group Chemical group 0.000 claims 1
• 125000001769 aryl amino group Chemical group 0.000 claims 1
• 125000004429 atom Chemical group 0.000 claims 1
• 125000000440 benzylamino group Chemical group [H]N(*)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
• 229910052799 carbon Inorganic materials 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
• 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
• 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 1
• UDMOIPYMZQQHPE-UHFFFAOYSA-N n-(2,2-dimethoxyethyl)benzamide Chemical compound COC(OC)CNC(=O)C1=CC=CC=C1 UDMOIPYMZQQHPE-UHFFFAOYSA-N 0.000 claims 1
• ZKSYUNLBFSOENV-UHFFFAOYSA-N n-(2-hydroxyethyl)benzamide Chemical compound OCCNC(=O)C1=CC=CC=C1 ZKSYUNLBFSOENV-UHFFFAOYSA-N 0.000 claims 1
• ODUBEYQKYAQFNS-UHFFFAOYSA-N n-(2-hydroxypropyl)-2-[[2-(2-hydroxypropylcarbamoyl)phenyl]disulfanyl]benzamide Chemical compound CC(O)CNC(=O)C1=CC=CC=C1SSC1=CC=CC=C1C(=O)NCC(C)O ODUBEYQKYAQFNS-UHFFFAOYSA-N 0.000 claims 1
• HVEKOIABBLJFPQ-UHFFFAOYSA-N n-(2-hydroxypropyl)benzamide Chemical compound CC(O)CNC(=O)C1=CC=CC=C1 HVEKOIABBLJFPQ-UHFFFAOYSA-N 0.000 claims 1
• YFCAIOHLFKWWGE-UHFFFAOYSA-N n-(3-hydroxypropyl)-2-[[2-(3-hydroxypropylcarbamoyl)phenyl]disulfanyl]benzamide Chemical compound OCCCNC(=O)C1=CC=CC=C1SSC1=CC=CC=C1C(=O)NCCCO YFCAIOHLFKWWGE-UHFFFAOYSA-N 0.000 claims 1
• 125000005184 naphthylamino group Chemical group C1(=CC=CC2=CC=CC=C12)N* 0.000 claims 1
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
• 125000006308 propyl amino group Chemical group 0.000 claims 1