DE60326864D1 - Proteininteraktionsdifferenzabbildung - Google Patents

Proteininteraktionsdifferenzabbildung

Info

Publication number
DE60326864D1
DE60326864D1 DE60326864T DE60326864T DE60326864D1 DE 60326864 D1 DE60326864 D1 DE 60326864D1 DE 60326864 T DE60326864 T DE 60326864T DE 60326864 T DE60326864 T DE 60326864T DE 60326864 D1 DE60326864 D1 DE 60326864D1
Authority
DE
Germany
Prior art keywords
protein interaction
difference picture
interaction difference
multicomponent
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60326864T
Other languages
English (en)
Inventor
William Rich
Egisto Boschetti
Lee O Lomas
Tai-Tung Yip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Application granted granted Critical
Publication of DE60326864D1 publication Critical patent/DE60326864D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60326864T 2002-07-24 2003-07-23 Proteininteraktionsdifferenzabbildung Expired - Lifetime DE60326864D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39864102P 2002-07-24 2002-07-24
US44553603P 2003-02-06 2003-02-06
PCT/US2003/023320 WO2004009798A2 (en) 2002-07-24 2003-07-23 Protein interaction difference mapping

Publications (1)

Publication Number Publication Date
DE60326864D1 true DE60326864D1 (de) 2009-05-07

Family

ID=30773100

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60326864T Expired - Lifetime DE60326864D1 (de) 2002-07-24 2003-07-23 Proteininteraktionsdifferenzabbildung

Country Status (7)

Country Link
US (1) US7348184B2 (de)
EP (1) EP1552302B1 (de)
JP (1) JP4587954B2 (de)
AT (1) ATE426808T1 (de)
AU (1) AU2003256806A1 (de)
DE (1) DE60326864D1 (de)
WO (1) WO2004009798A2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040229294A1 (en) 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
US7402397B2 (en) 2002-05-21 2008-07-22 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
WO2005037071A2 (en) 2003-10-14 2005-04-28 Monogram Biosciences, Inc. Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy
US7707134B2 (en) * 2005-01-14 2010-04-27 Siemens Medical Solutions Usa, Inc. System and method for molecular diagnosis of depression based on boosting classification
US7672916B2 (en) * 2005-08-16 2010-03-02 The Trustees Of Columbia University In The City Of New York Methods, systems, and media for music classification
US20080023630A1 (en) * 2005-11-22 2008-01-31 Ciphergen Biosystems Inc. Polymer probe doped with conductive material for mass spectrometry
AU2006325531B2 (en) 2005-12-13 2012-04-19 Exthera Medical Corporation Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
JP2009524829A (ja) * 2006-01-27 2009-07-02 イースタン バージニア メディカル スクール ヒトivf由来胚のプロテオームフィンガープリンティング:発生能のバイオマーカーの同定法
EP2347428A1 (de) * 2008-10-10 2011-07-27 Excellims Corporation Verfahren und vorrichtung zur trennung chemischer und biologischer proben
ES2861359T3 (es) 2009-12-01 2021-10-06 Exthera Medical Corp Dispositivo para eliminar citoquinas de la sangre con polisacáridos inmovilizados en superficie
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
US9746458B2 (en) * 2011-04-27 2017-08-29 Loma Linda University Medical Center Dynactin subunit p62 biomarker for neurological conditions
MX356413B (es) * 2012-06-07 2018-05-29 Somalogic Inc Ensayos multiplexados basados en aptámeros.
ES2647577T3 (es) 2012-06-13 2017-12-22 Exthera Medical Corporation Uso de heparina y carbohidratos para tratar el cáncer
KR20150090072A (ko) 2012-10-23 2015-08-05 카리스 라이프 사이언스 스위스 홀딩스 게엠베하 압타머 및 이의 용도
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
EP2935628B1 (de) 2012-12-19 2018-03-21 Caris Life Sciences Switzerland Holdings GmbH Zusammensetzungen und verfahren für aptamer-screening
JP6648009B2 (ja) 2013-06-24 2020-02-14 エクステラ・メディカル・コーポレーション マンノース被覆基材を含有する血液濾過システム
AU2014346668C1 (en) 2013-11-08 2018-04-26 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
DE15782250T1 (de) 2014-04-24 2017-08-10 Exthera Medical Corporation Verfahren zur Entfernung von Bakterien aus Blut unter Verwendung einer hohen Durchflussrate
CN106714669B (zh) 2014-09-22 2021-05-14 艾克塞拉医疗公司 可穿戴的血液灌流装置
EP3112869A1 (de) * 2015-06-30 2017-01-04 IMEC vzw Sensorvorrichtung
US10386351B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using gas species diffusion
US11988662B2 (en) 2015-12-07 2024-05-21 Nanohmics, Inc. Methods for detecting and quantifying gas species analytes using differential gas species diffusion
US10386365B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using ionic species diffusion
EP3422943A4 (de) 2016-03-02 2019-10-16 ExThera Medical Corporation Verfahren zur behandlung von arzneimittelintoxikation
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
ITUA20163876A1 (it) * 2016-05-27 2017-11-27 Univ Del Salento Biorecettore per ioni metallici.
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
GB2595583A (en) 2018-11-07 2021-12-01 Seer Inc Compositions, methods and systems for protein corona analysis and uses thereof
EP3969014A4 (de) 2019-05-16 2023-01-25 ExThera Medical Corporation Verfahren zur modulation der endothelialen glycocalyxstruktur

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234811A (en) * 1991-09-27 1993-08-10 The Scripps Research Institute Assay for a new gaucher disease mutation
US5571729A (en) * 1992-06-17 1996-11-05 Wako Pure Chemical Industries, Ltd. Process for separating complex
WO1994028418A1 (en) * 1993-05-28 1994-12-08 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6548021B1 (en) * 1997-10-10 2003-04-15 President And Fellows Of Harvard College Surface-bound, double-stranded DNA protein arrays
US6265715B1 (en) * 1998-02-02 2001-07-24 Helene Perreault Non-porous membrane for MALDI-TOFMS
AU4338300A (en) * 1999-04-09 2000-11-14 Geron Corporation A second mammalian tankyrase
AU2001261392A1 (en) * 2000-05-12 2001-11-26 Admetric Biochem Inc. High throughput chromatographic systems
US20030091976A1 (en) 2001-11-14 2003-05-15 Ciphergen Biosystems, Inc. Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry

Also Published As

Publication number Publication date
WO2004009798A2 (en) 2004-01-29
EP1552302B1 (de) 2009-03-25
JP4587954B2 (ja) 2010-11-24
AU2003256806A8 (en) 2004-02-09
ATE426808T1 (de) 2009-04-15
US20040146937A1 (en) 2004-07-29
US7348184B2 (en) 2008-03-25
WO2004009798A3 (en) 2004-10-07
AU2003256806A1 (en) 2004-02-09
JP2005534043A (ja) 2005-11-10
EP1552302A2 (de) 2005-07-13
EP1552302A4 (de) 2006-09-13

Similar Documents

Publication Publication Date Title
ATE426808T1 (de) Proteininteraktionsdifferenzabbildung
EA200400063A1 (ru) Антитела к опг лиганду
EP1545582A4 (de) Von amyolid-beta abgeleitete diffundierbare liganden (addls), addl-ersatzstoffe, addl-bindungsmoleküle und verwendungen davon
WO2003072803A3 (en) Nanostructures containing antibody assembly units
DK0600866T3 (da) Præparater og fremgangsmåder til identifikation af biologisk aktive molekyler
WO2005118857A3 (en) Methods and agents for screening for compounds capable of modulating vegf expression
AU2003224674A8 (en) Compounds and methods for analyzing the proteome
EP1623227A4 (de) Proteine, sensoren und verfahren zur charakterisierung von analyten damit
DE502006008140D1 (de) Verwendung von grenzflächenaktiven, nicht-enzymatischen proteinen für die textilwäsche
ATE366419T1 (de) Auswahl von epitop-bindungsfähigen verbindungen aus bibliotheken
MY147996A (en) Sequential protein isolation and purification schemes by affinity chromatography.
SE9604815D0 (sv) A metod of diagnosis
EP0753744A3 (de) Bestimmung einer an Immunophilin gebundenen immunosuppressiven Verbindung
WO2002014351A3 (en) α7 NICOTINIC RECEPTOR PEPTIDES AS LIGANDS FOR β AMYLOID P EPTIDES
EA200801174A1 (ru) Антитела-миметики glp-2, полипептиды, композиции, способы и применения
WO2003072595A3 (en) Methods and products based on oligomerization of stress proteins
ATE437185T1 (de) Gegen das gemeinsame epitop von mutierten p53 gerichtete humane synthetische einzelkettenantikörper und anwendungen davon
ATE389881T1 (de) Detektion von kleinen molekülen mit piezo- elektrischem sensor
WO1999030165A3 (en) Processes for identifying a solvent condition suitable for determining a biophysical property of a protein
ITPN20020017U1 (it) Vaschetta per sostanze detergenti e macchina lavatrice comprendente detta vaschetta.
WO2005041631A3 (en) Endotheliase-1 ligands
TR200003467T2 (tr) Neisseria meningitidis antijenik polipeptidler, mütekabil polinükleotidler ve koruyucu antikorlar
DE69005088D1 (de) Vibrierende seismische Quelle, insbesondere anwendbar in Bohrlöchern.
EP1480124A3 (de) Verfahren und Vorrichtung zur Zuordnung von Betriebsmittelpools zu Betriebssystempartitionen
ATA13642000A (de) Vorrichtung zum lageverändern und feststellen von teilen, z.b. lordosenstützen, von möbeln zum sitzen und/oder liegen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition