DE60322882D1 - T zell-subpopulation zur regelung der darmimmunität - Google Patents
T zell-subpopulation zur regelung der darmimmunitätInfo
- Publication number
- DE60322882D1 DE60322882D1 DE60322882T DE60322882T DE60322882D1 DE 60322882 D1 DE60322882 D1 DE 60322882D1 DE 60322882 T DE60322882 T DE 60322882T DE 60322882 T DE60322882 T DE 60322882T DE 60322882 D1 DE60322882 D1 DE 60322882D1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- polypeptide
- activity
- vivo
- regulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001105 regulatory effect Effects 0.000 title abstract 3
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 5
- 230000000694 effects Effects 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000028774 intestinal disease Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/143,822 US7829289B2 (en) | 2002-05-14 | 2002-05-14 | T cell subpopulation regulating gut immunity |
| PCT/EP2003/004992 WO2003095606A2 (en) | 2002-05-14 | 2003-05-13 | A t cell subpopulation regulating gut immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60322882D1 true DE60322882D1 (de) | 2008-09-25 |
Family
ID=29418471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60322882T Expired - Lifetime DE60322882D1 (de) | 2002-05-14 | 2003-05-13 | T zell-subpopulation zur regelung der darmimmunität |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7829289B2 (de) |
| EP (1) | EP1504261B1 (de) |
| AT (1) | ATE404865T1 (de) |
| AU (1) | AU2003240631A1 (de) |
| DE (1) | DE60322882D1 (de) |
| DK (1) | DK1504261T3 (de) |
| ES (1) | ES2312782T3 (de) |
| WO (1) | WO2003095606A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7829289B2 (en) * | 2002-05-14 | 2010-11-09 | Institut National De La Sante Et De Recherche Medicale | T cell subpopulation regulating gut immunity |
| WO2008087219A1 (en) * | 2007-01-19 | 2008-07-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for regulating t cell activity |
| JP2011503104A (ja) | 2007-11-09 | 2011-01-27 | カリフォルニア インスティテュート オブ テクノロジー | 免疫調節化合物ならびに関連組成物および方法 |
| US20100275282A1 (en) * | 2009-04-23 | 2010-10-28 | Round June L | Methods and systems for identifying immunomodulatory substances |
| ES2694100T3 (es) | 2010-04-07 | 2018-12-18 | California Institute Of Technology | Vehículo para distribuir un compuesto en una membrana mucosa y composiciones, procedimientos y sistemas relacionados |
| WO2013009945A1 (en) | 2011-07-12 | 2013-01-17 | The Brigham And Women's Hospital, Inc. | Lipid-containing psa compositions, methods of isolation and methods of use thereof |
| US10011602B2 (en) | 2012-07-06 | 2018-07-03 | The University Of Melbourne | Immunological reagents and uses therefor |
| EP2994161B1 (de) | 2013-05-10 | 2020-10-28 | California Institute of Technology | Probiotische prävention und behandlung von dickdarmkrebs |
| US11331335B2 (en) | 2015-06-10 | 2022-05-17 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
| WO2017031431A1 (en) | 2015-08-19 | 2017-02-23 | President And Fellows Of Harvard College | Lipidated psa compositions and methods |
| EP3484441A4 (de) | 2016-07-15 | 2020-03-18 | President and Fellows of Harvard College | Glycolipidzusammensetzungen und verfahren zur verwendung |
| AU2018231405B2 (en) * | 2017-03-07 | 2024-02-08 | Universität Basel | MR1 restricted T cell receptors for cancer immunotherapy |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7829289B2 (en) * | 2002-05-14 | 2010-11-09 | Institut National De La Sante Et De Recherche Medicale | T cell subpopulation regulating gut immunity |
-
2002
- 2002-05-14 US US10/143,822 patent/US7829289B2/en not_active Expired - Fee Related
-
2003
- 2003-05-13 EP EP03730020A patent/EP1504261B1/de not_active Expired - Lifetime
- 2003-05-13 DK DK03730020T patent/DK1504261T3/da active
- 2003-05-13 AT AT03730020T patent/ATE404865T1/de active
- 2003-05-13 ES ES03730020T patent/ES2312782T3/es not_active Expired - Lifetime
- 2003-05-13 AU AU2003240631A patent/AU2003240631A1/en not_active Abandoned
- 2003-05-13 WO PCT/EP2003/004992 patent/WO2003095606A2/en active IP Right Grant
- 2003-05-13 DE DE60322882T patent/DE60322882D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1504261T3 (da) | 2009-01-05 |
| WO2003095606A2 (en) | 2003-11-20 |
| AU2003240631A1 (en) | 2003-11-11 |
| ES2312782T3 (es) | 2009-03-01 |
| US7829289B2 (en) | 2010-11-09 |
| WO2003095606A3 (en) | 2004-03-25 |
| EP1504261A2 (de) | 2005-02-09 |
| US20030215808A1 (en) | 2003-11-20 |
| ATE404865T1 (de) | 2008-08-15 |
| AU2003240631A8 (en) | 2003-11-11 |
| EP1504261B1 (de) | 2008-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |