DE60321487D1 - Verfahren zur identifizierung und quantifizierung von proteinen, isoformen des angiotensin i umsetzenden enzyms - Google Patents
Verfahren zur identifizierung und quantifizierung von proteinen, isoformen des angiotensin i umsetzenden enzymsInfo
- Publication number
- DE60321487D1 DE60321487D1 DE60321487T DE60321487T DE60321487D1 DE 60321487 D1 DE60321487 D1 DE 60321487D1 DE 60321487 T DE60321487 T DE 60321487T DE 60321487 T DE60321487 T DE 60321487T DE 60321487 D1 DE60321487 D1 DE 60321487D1
- Authority
- DE
- Germany
- Prior art keywords
- isoforms
- angiotensin
- identifying
- quantifying proteins
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000001708 Protein Isoforms Human genes 0.000 title abstract 3
- 108010029485 Protein Isoforms Proteins 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 abstract 1
- 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 abstract 1
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/007—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isoenzyme profiles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
- G01N2410/02—Angiotensins; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0206903A BRPI0206903B8 (pt) | 2002-12-20 | 2002-12-20 | método de prognóstico de uma predisposição para o desenvolvimento de hipertensão e lesões no coração, sistema nervoso, sistema vascular ou rins, e uso da isoforma de 90 kda da enzima conversora de angiotensina i no referido método |
| PCT/BR2003/000202 WO2004057020A1 (en) | 2002-12-20 | 2003-12-22 | Method of identification and quantification of proteins, isoforms of the angiotensin i converting enzyme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60321487D1 true DE60321487D1 (de) | 2008-07-17 |
Family
ID=36165445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60321487T Expired - Lifetime DE60321487D1 (de) | 2002-12-20 | 2003-12-22 | Verfahren zur identifizierung und quantifizierung von proteinen, isoformen des angiotensin i umsetzenden enzyms |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7687237B2 (de) |
| EP (1) | EP1573059B1 (de) |
| JP (1) | JP2006510365A (de) |
| AT (1) | ATE397671T1 (de) |
| AU (1) | AU2003287794A1 (de) |
| BR (1) | BRPI0206903B8 (de) |
| DE (1) | DE60321487D1 (de) |
| ES (1) | ES2310251T3 (de) |
| PT (1) | PT1573059E (de) |
| WO (1) | WO2004057020A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1955075A2 (de) * | 2005-11-30 | 2008-08-13 | mosaiques diagnostics and therapeutics AG | Polypeptidmarker zur diagnostik und beurteilung vaskulären erkrankungen |
| US20160003857A1 (en) * | 2014-07-02 | 2016-01-07 | Cecil Bennett | Methods and systems for detecting polypharmacy |
| RU2600442C1 (ru) * | 2015-11-13 | 2016-10-20 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт медицины труда" (ФГБНУ "НИИ МТ") | Способ определения риска развития артериальной гипертензии |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153386A (en) * | 1992-09-30 | 2000-11-28 | University Of Utah Research Foundation | Method to determine predisposition to hypertension |
| JP2001510328A (ja) * | 1996-10-04 | 2001-07-31 | ミカエル マルヴァニー | 高血圧マーカー |
| US6610497B1 (en) * | 1997-12-11 | 2003-08-26 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| GB9810085D0 (en) * | 1998-05-11 | 1998-07-08 | Gemini Research Limited | Polymorphism in a nitric oxide synthase gene |
| US7028537B2 (en) * | 2001-09-20 | 2006-04-18 | Esa Biosciences, Inc. | Coupling electrochemistry to mass spectrometry and high performance liquid chromatography |
-
2002
- 2002-12-20 BR BRPI0206903A patent/BRPI0206903B8/pt not_active IP Right Cessation
-
2003
- 2003-12-22 JP JP2004560930A patent/JP2006510365A/ja active Pending
- 2003-12-22 AU AU2003287794A patent/AU2003287794A1/en not_active Abandoned
- 2003-12-22 EP EP03779591A patent/EP1573059B1/de not_active Expired - Lifetime
- 2003-12-22 ES ES03779591T patent/ES2310251T3/es not_active Expired - Lifetime
- 2003-12-22 DE DE60321487T patent/DE60321487D1/de not_active Expired - Lifetime
- 2003-12-22 WO PCT/BR2003/000202 patent/WO2004057020A1/en active IP Right Grant
- 2003-12-22 AT AT03779591T patent/ATE397671T1/de active
- 2003-12-22 US US10/540,193 patent/US7687237B2/en not_active Expired - Fee Related
- 2003-12-22 PT PT03779591T patent/PT1573059E/pt unknown
-
2010
- 2010-02-23 US US12/710,770 patent/US20100209954A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7687237B2 (en) | 2010-03-30 |
| US20060057739A1 (en) | 2006-03-16 |
| WO2004057020A1 (en) | 2004-07-08 |
| ATE397671T1 (de) | 2008-06-15 |
| EP1573059A1 (de) | 2005-09-14 |
| EP1573059B1 (de) | 2008-06-04 |
| BRPI0206903B8 (pt) | 2021-07-27 |
| WO2004057020A8 (en) | 2004-09-30 |
| PT1573059E (pt) | 2008-09-16 |
| AU2003287794A8 (en) | 2004-07-14 |
| BRPI0206903B1 (pt) | 2015-09-08 |
| US20100209954A1 (en) | 2010-08-19 |
| AU2003287794A1 (en) | 2004-07-14 |
| BR0206903A (pt) | 2004-08-10 |
| ES2310251T3 (es) | 2009-01-01 |
| JP2006510365A (ja) | 2006-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: HOESSLE PATENTANWAELTE PARTNERSCHAFT, 70173 STUTTG |