DE60236688D1 - Hyaluronansynthase-gene und expression davon - Google Patents

Hyaluronansynthase-gene und expression davon

Info

Publication number
DE60236688D1
DE60236688D1 DE60236688T DE60236688T DE60236688D1 DE 60236688 D1 DE60236688 D1 DE 60236688D1 DE 60236688 T DE60236688 T DE 60236688T DE 60236688 T DE60236688 T DE 60236688T DE 60236688 D1 DE60236688 D1 DE 60236688D1
Authority
DE
Germany
Prior art keywords
expression
synthase genes
hyaluronate synthase
host cell
bacillus host
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60236688T
Other languages
English (en)
Inventor
Paul L Deangelis
Paul H Weigel
Kshama Kumari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oklahoma State University
University of Oklahoma
Original Assignee
Oklahoma State University
University of Oklahoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma State University, University of Oklahoma filed Critical Oklahoma State University
Application granted granted Critical
Publication of DE60236688D1 publication Critical patent/DE60236688D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60236688T 2001-06-13 2002-06-13 Hyaluronansynthase-gene und expression davon Expired - Lifetime DE60236688D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29774401P 2001-06-13 2001-06-13
US29778801P 2001-06-13 2001-06-13
PCT/US2002/018915 WO2003060063A2 (en) 1999-12-21 2002-06-13 Hyaluronan synthase genes and expression thereof

Publications (1)

Publication Number Publication Date
DE60236688D1 true DE60236688D1 (de) 2010-07-22

Family

ID=31498148

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60236688T Expired - Lifetime DE60236688D1 (de) 2001-06-13 2002-06-13 Hyaluronansynthase-gene und expression davon

Country Status (10)

Country Link
EP (1) EP1481052B1 (de)
JP (1) JP2005514059A (de)
CN (2) CN1620511A (de)
AT (1) ATE470708T1 (de)
AU (2) AU2002365206B2 (de)
CA (1) CA2451443C (de)
DE (1) DE60236688D1 (de)
DK (1) DK1481052T3 (de)
ES (1) ES2346196T3 (de)
WO (1) WO2003060063A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212928B1 (pl) 2001-12-21 2012-12-31 Novozymes Biopolymer As Sposób wytwarzania kwasu hialuronowego i komórka gospodarz Bacillus
AU2008200910C1 (en) * 2001-12-21 2012-11-22 Novozymes A/S Methods for producing hyaluronan in a recombinant host cell
AU2005230844A1 (en) * 2004-03-31 2005-10-20 Novozymes Biopharma Dk A/S Methods for producing hyaluronic acid in a bacillus cell
EP1696032A1 (de) 2005-02-23 2006-08-30 Bayer CropScience GmbH Verfahren und Mittel zur Herstellung von Hyaluronan in Pilzen
JP4639904B2 (ja) 2005-03-30 2011-02-23 チッソ株式会社 蛍光活性を有するルシフェラーゼの活性増強方法
JP4609177B2 (ja) 2005-04-28 2011-01-12 チッソ株式会社 カルシウム結合型発光蛋白質溶液の発光時間延長方法
US20080038780A1 (en) * 2006-02-15 2008-02-14 Novozymes Biopolymer A/S Production of low molecular weight hyaluronic acid
GB0610498D0 (en) * 2006-05-26 2006-07-05 Univ York Modified molecule
WO2009026635A1 (en) * 2007-08-31 2009-03-05 The University Of Queensland Production of hyaluronic acid
CN102559559A (zh) * 2012-02-21 2012-07-11 山东福瑞达生物医药有限公司 一种芽孢杆菌及采用该菌种生产透明质酸酶的方法
WO2013123791A1 (zh) * 2012-02-21 2013-08-29 华熙福瑞达生物医药有限公司 一种芽孢杆菌、一种透明质酸酶、以及其用途
CN108587918A (zh) * 2018-05-30 2018-09-28 昆明理工大学 一种基于兼养微藻油脂积累的方法
CN108841862A (zh) * 2018-07-19 2018-11-20 中国农业科学院北京畜牧兽医研究所 一种含有ha蛋白融合标签的植物表达质粒载体及其载体的构建方法
CN111518736B (zh) * 2019-10-24 2022-04-15 华熙生物科技股份有限公司 一种高效合成高纯度透明质酸及其寡聚糖的重组谷氨酸棒状杆菌
CN115315242A (zh) * 2020-04-22 2022-11-08 株式会社资生堂 透明质酸产生促进剂
EP4067499A1 (de) * 2021-04-01 2022-10-05 Givaudan SA Hyaluronsäureproduzierende rekombinante zellen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455304B1 (en) * 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
US6492150B1 (en) * 1996-07-03 2002-12-10 Clear Colutions Biotech, Inc. Gene encoding hyaluronan synthase
IL138803A0 (en) * 1998-04-02 2001-10-31 Univ Oklahoma Nucleic acid encoding hyaluronan synthase
EP1478746A4 (de) * 2001-12-03 2005-06-29 Regents For The University Of Hyaluronsynthasen und verfahren zur herstellung und verwendung davon
PL212928B1 (pl) * 2001-12-21 2012-12-31 Novozymes Biopolymer As Sposób wytwarzania kwasu hialuronowego i komórka gospodarz Bacillus

Also Published As

Publication number Publication date
AU2008202651A1 (en) 2008-07-10
DK1481052T3 (da) 2010-09-20
EP1481052A2 (de) 2004-12-01
WO2003060063A3 (en) 2004-09-16
CN1620511A (zh) 2005-05-25
EP1481052A4 (de) 2005-11-16
AU2008202651B2 (en) 2011-06-02
AU2002365206A1 (en) 2003-07-30
CN101709285A (zh) 2010-05-19
WO2003060063A2 (en) 2003-07-24
AU2002365206B2 (en) 2008-03-20
ATE470708T1 (de) 2010-06-15
CA2451443C (en) 2013-05-28
CN101709285B (zh) 2014-03-26
JP2005514059A (ja) 2005-05-19
CA2451443A1 (en) 2003-07-24
EP1481052B1 (de) 2010-06-09
ES2346196T3 (es) 2010-10-13

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