DE60235393D1 - Desmin-gen mit neuer punktmutation, die dilatationscardiomyopathie verursacht - Google Patents

Desmin-gen mit neuer punktmutation, die dilatationscardiomyopathie verursacht

Info

Publication number
DE60235393D1
DE60235393D1 DE60235393T DE60235393T DE60235393D1 DE 60235393 D1 DE60235393 D1 DE 60235393D1 DE 60235393 T DE60235393 T DE 60235393T DE 60235393 T DE60235393 T DE 60235393T DE 60235393 D1 DE60235393 D1 DE 60235393D1
Authority
DE
Germany
Prior art keywords
scardiomyopathy
point mutation
new point
desmin gene
causes dilation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235393T
Other languages
English (en)
Inventor
Aiji Sakamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Japan Science and Technology Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science and Technology Agency filed Critical Japan Science and Technology Agency
Application granted granted Critical
Publication of DE60235393D1 publication Critical patent/DE60235393D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4717—Plasma globulins, lactoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0375—Animal model for cardiovascular diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60235393T 2001-11-12 2002-10-11 Desmin-gen mit neuer punktmutation, die dilatationscardiomyopathie verursacht Expired - Lifetime DE60235393D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001345491 2001-11-12
JP2002034379A JP4170633B2 (ja) 2001-11-12 2002-02-12 拡張型心筋症の原因となる新規点突然変異を有するデスミン遺伝子
PCT/JP2002/010569 WO2003042386A1 (en) 2001-11-12 2002-10-11 Desmin gene having novel point mutation causative of dilated cardiomyopathy

Publications (1)

Publication Number Publication Date
DE60235393D1 true DE60235393D1 (de) 2010-04-01

Family

ID=26624460

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235393T Expired - Lifetime DE60235393D1 (de) 2001-11-12 2002-10-11 Desmin-gen mit neuer punktmutation, die dilatationscardiomyopathie verursacht

Country Status (5)

Country Link
US (2) US7297487B2 (de)
EP (1) EP1443111B1 (de)
JP (1) JP4170633B2 (de)
DE (1) DE60235393D1 (de)
WO (1) WO2003042386A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0428255D0 (en) * 2004-12-23 2005-01-26 Health Prot Agency Detection of nucleic acid mutations
JP5094725B2 (ja) * 2005-10-04 2012-12-12 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ Ｈｉｖインテグラーゼ阻害剤
CN111004849B (zh) * 2019-12-13 2022-08-26 南京艾迪康医学检验所有限公司 检测cdh1基因的多个位点突变的引物、方法和试剂盒
CN112410418A (zh) * 2020-11-23 2021-02-26 复旦大学附属中山医院 一种扩张型心肌病分子标志物

Also Published As

Publication number Publication date
WO2003042386A1 (en) 2003-05-22
JP2003204795A (ja) 2003-07-22
US7297487B2 (en) 2007-11-20
JP4170633B2 (ja) 2008-10-22
US7825292B1 (en) 2010-11-02
EP1443111A1 (de) 2004-08-04
EP1443111A4 (de) 2005-06-22
EP1443111B1 (de) 2010-02-17
US20050155092A1 (en) 2005-07-14
HK1064408A1 (en) 2005-01-28

Similar Documents

Publication Publication Date Title
NL1021691A1 (nl) Smeermiddel-basisolien met verbeterde opbrengst.
ITTO20020167A1 (it) Ciclo di regrigerazione.
NL1021276A1 (nl) Gereedschap met verglaasd superslijpmiddel en vervaardigingswerkwijze.
NO20040654L (no) Gassmikrosfaere-liposomkompositter.
NL1024881A1 (nl) PPAR-activatoren.
MXPA03006276A (es) Auxiliar reologico, su preparacion y uso.
IT1320240B1 (it) Macchina curvatrice di profilati.
DE60112333D1 (de) Vertikale, kastenlose formgiessmaschine
ITTO20010694A1 (it) Metodo di crittografia.
DZ3441A1 (fr) Nouvelles phenylpiperazines.
ITRM20020455A1 (it) Piegatrice.
IT1315627B1 (it) Impianto idroelettrico con condotte forzate disposte sul letto di unfiume.
ITMI20021328A1 (it) Nuove piperazine 1,4 - disostituite
ITRM20010304A0 (it) Metodo di codificazione, in particolare di codificazione numerica.
ITVR20020073A1 (it) Manicotto di giunzione.
ES1050585Y (es) Plantilla adherente para calzado.
ES1050491Y (es) Chupete infantil.
ES1052636Y (es) Calzado con plantilla.
ES1049741Y (es) Moldura flocada.
ITTO20001039A0 (it) Metodo di interrogazione di banche dati.
ITMT20010003U1 (it) Dissipatore di calore.
ITBO20020533A1 (it) Decoro scanalato.
ES1047974Y (es) Teclado multiteclas configurable.
NO20012236L (no) SötpÕleggprodukt, samt dets fremstilling og anvendelse
ITVR20010038V0 (it) Profilato perimetrale universale.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition