DE60233520D1 - Markierungsreagens und anwendungsverfahren - Google Patents
Markierungsreagens und anwendungsverfahrenInfo
- Publication number
- DE60233520D1 DE60233520D1 DE60233520T DE60233520T DE60233520D1 DE 60233520 D1 DE60233520 D1 DE 60233520D1 DE 60233520 T DE60233520 T DE 60233520T DE 60233520 T DE60233520 T DE 60233520T DE 60233520 D1 DE60233520 D1 DE 60233520D1
- Authority
- DE
- Germany
- Prior art keywords
- lysine
- labels
- present
- polypeptide
- terminal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/36—Radio frequency spectrometers, e.g. Bennett-type spectrometers, Redhead-type spectrometers
- H01J49/38—Omegatrons ; using ion cyclotron resonance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33298801P | 2001-11-05 | 2001-11-05 | |
US38583502P | 2002-06-03 | 2002-06-03 | |
US41038202P | 2002-09-12 | 2002-09-12 | |
PCT/US2002/035581 WO2003056299A2 (en) | 2001-11-05 | 2002-11-05 | Labeling reagent and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60233520D1 true DE60233520D1 (de) | 2009-10-08 |
Family
ID=27406887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60233520T Expired - Fee Related DE60233520D1 (de) | 2001-11-05 | 2002-11-05 | Markierungsreagens und anwendungsverfahren |
Country Status (7)
Country | Link |
---|---|
US (2) | US20030228700A1 (de) |
EP (1) | EP1451207B1 (de) |
JP (1) | JP4328625B2 (de) |
AT (1) | ATE441115T1 (de) |
AU (1) | AU2002365152A1 (de) |
DE (1) | DE60233520D1 (de) |
WO (1) | WO2003056299A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6977370B1 (en) * | 2003-04-07 | 2005-12-20 | Ciphergen Biosystems, Inc. | Off-resonance mid-IR laser desorption ionization |
CA2545685A1 (en) * | 2003-11-14 | 2005-06-02 | Irm Llc | Fluorous labeling for selective processing of biologically-derived samples |
US20070054345A1 (en) | 2004-05-19 | 2007-03-08 | Hunter Christie L | Expression quantification using mass spectrometry |
WO2006017208A1 (en) * | 2004-07-12 | 2006-02-16 | Applera Corporation | Mass tags for quantitative analyses |
US20070048752A1 (en) | 2004-07-12 | 2007-03-01 | Applera Corporation | Mass tags for quantitative analyses |
US20060014293A1 (en) * | 2004-07-16 | 2006-01-19 | Joyce Timothy H | Lock mass ions for use with derivatized peptides for de novo sequencing using tandem mass spectrometry |
US7371514B2 (en) | 2004-07-16 | 2008-05-13 | Agilent Technologies, Inc. | Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry |
US20060183238A1 (en) | 2005-02-09 | 2006-08-17 | Applera Corporation | Amine-containing compound analysis methods |
JP2010537172A (ja) * | 2007-08-21 | 2010-12-02 | エムディーエス アナリティカル テクノロジーズ, ア ビジネス ユニット オブ エムディーエス インコーポレイテッド, ドゥーイング ビジネス スルー イッツ サイエックス ディビジョン | 質量割り当て精度を向上させる方法 |
KR101081053B1 (ko) | 2008-07-18 | 2011-11-07 | 포항공과대학교 산학협력단 | 가변질량 라벨링제와 이를 이용한 아미노산 서열 및 단백질정량 동시 분석방법 |
WO2010109022A1 (en) | 2009-03-27 | 2010-09-30 | Universitetet I Oslo | Quantitative proteomics method |
US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
US9625469B2 (en) | 2011-06-23 | 2017-04-18 | Board Of Regents, The University Of Texas System | Identifying peptides at the single molecule level |
JP6281349B2 (ja) * | 2014-03-19 | 2018-02-21 | 株式会社島津製作所 | 質量分析用ペプチド混合物試料の調製方法 |
US10545153B2 (en) | 2014-09-15 | 2020-01-28 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
CA2999331A1 (en) | 2015-10-14 | 2017-04-20 | Wisconsin Alumni Research Foundation | Mass defect-based multiplex dimethyl pyrimidinyl ornithine (dipyro) tags for high-throughput quantitative proteomics and peptidomics |
JP6857569B2 (ja) * | 2017-07-26 | 2021-04-14 | 日本電子株式会社 | 質量分析システム及び質量スペクトル表示方法 |
CN116813693B (zh) * | 2023-08-29 | 2023-12-01 | 苏州金顶生物有限公司 | 一种用于多肽合成的标签化合物及其在多肽合成中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB869977A (en) * | 1957-12-26 | 1961-06-07 | Pfizer & Co C | Diazacycloalkenes and the preparation thereof |
FI832053L (fi) * | 1982-06-10 | 1983-12-11 | Syntex Inc | Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande |
US4530920A (en) * | 1983-11-07 | 1985-07-23 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist |
US4659693A (en) * | 1984-04-30 | 1987-04-21 | Syntex (U.S.A.) Inc. | N,N'-dialkyl substituted guanidino amino acyl residue substituted GRF-analog peptides |
US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
CA2136717A1 (en) * | 1992-05-29 | 1993-12-09 | Brian T. Chait | Method and product for the sequence determination of peptides using a mass spectrometer |
US5859295A (en) * | 1994-12-05 | 1999-01-12 | University Of Kentucky Research Foundation | Canavanine analogs and their use as chemotherapeutic agents |
EP1688987A1 (de) * | 1999-04-06 | 2006-08-09 | Micromass UK Limited | Verfahren zur Identifizierung von Peptiden und Proteinen mittels Massenspektromterie |
-
2002
- 2002-11-05 JP JP2003556774A patent/JP4328625B2/ja not_active Expired - Fee Related
- 2002-11-05 WO PCT/US2002/035581 patent/WO2003056299A2/en active Application Filing
- 2002-11-05 EP EP02803304A patent/EP1451207B1/de not_active Expired - Lifetime
- 2002-11-05 US US10/289,009 patent/US20030228700A1/en not_active Abandoned
- 2002-11-05 AU AU2002365152A patent/AU2002365152A1/en not_active Abandoned
- 2002-11-05 DE DE60233520T patent/DE60233520D1/de not_active Expired - Fee Related
- 2002-11-05 AT AT02803304T patent/ATE441115T1/de not_active IP Right Cessation
-
2007
- 2007-05-07 US US11/745,358 patent/US20080242838A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003056299A2 (en) | 2003-07-10 |
JP4328625B2 (ja) | 2009-09-09 |
US20030228700A1 (en) | 2003-12-11 |
WO2003056299A3 (en) | 2004-02-26 |
EP1451207A2 (de) | 2004-09-01 |
ATE441115T1 (de) | 2009-09-15 |
JP2005514404A (ja) | 2005-05-19 |
EP1451207B1 (de) | 2009-08-26 |
AU2002365152A8 (en) | 2003-07-15 |
AU2002365152A1 (en) | 2003-07-15 |
US20080242838A1 (en) | 2008-10-02 |
EP1451207A4 (de) | 2005-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |