DE60232742D1 - Ul16-bindungsprotein 4 - Google Patents
Ul16-bindungsprotein 4Info
- Publication number
- DE60232742D1 DE60232742D1 DE60232742T DE60232742T DE60232742D1 DE 60232742 D1 DE60232742 D1 DE 60232742D1 DE 60232742 T DE60232742 T DE 60232742T DE 60232742 T DE60232742 T DE 60232742T DE 60232742 D1 DE60232742 D1 DE 60232742D1
- Authority
- DE
- Germany
- Prior art keywords
- ulbp4
- binding protein
- cells
- encoding
- vectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101001132524 Homo sapiens Retinoic acid early transcript 1E Proteins 0.000 title abstract 4
- 102100033964 Retinoic acid early transcript 1E Human genes 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 1
- 239000012642 immune effector Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 210000000822 natural killer cell Anatomy 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32725201P | 2001-10-04 | 2001-10-04 | |
| PCT/US2002/031994 WO2003029436A2 (en) | 2001-10-04 | 2002-10-04 | Ul16 binding protein 4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60232742D1 true DE60232742D1 (de) | 2009-08-06 |
Family
ID=23275763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60232742T Expired - Lifetime DE60232742D1 (de) | 2001-10-04 | 2002-10-04 | Ul16-bindungsprotein 4 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7563450B2 (enExample) |
| EP (1) | EP1451333B1 (enExample) |
| JP (1) | JP2005523681A (enExample) |
| AT (1) | ATE434624T1 (enExample) |
| AU (1) | AU2002340118B2 (enExample) |
| CA (1) | CA2462790A1 (enExample) |
| DE (1) | DE60232742D1 (enExample) |
| MX (1) | MXPA04003057A (enExample) |
| PL (1) | PL373594A1 (enExample) |
| WO (1) | WO2003029436A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2483343A1 (en) * | 2002-04-22 | 2003-10-30 | Fred Hutchinson Cancer Research Center | Soluble mic polypeptides as markers for diagnosis, prognosis and treatment of cancer and autoimmune diseases or conditions |
| AU2003270063A1 (en) * | 2002-09-04 | 2004-03-29 | The Trustees Of The University Of Pennsylvania | Immune cell receptor ligand and immune cell receptor |
| US7666417B2 (en) * | 2003-04-22 | 2010-02-23 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating autoimmune diseases or conditions |
| US7834155B2 (en) | 2003-07-21 | 2010-11-16 | Immunogen Inc. | CA6 antigen-specific cytotoxic conjugate and methods of using the same |
| EP1660513B9 (en) * | 2003-07-21 | 2012-04-04 | ImmunoGen, Inc. | A ca6 antigen-specific cytotoxic conjugate and methods of using the same |
| US7998481B2 (en) | 2004-04-05 | 2011-08-16 | The Regents Of The University Of California | Modulation of NKG2D for treating or preventing solid organ allograft rejection |
| DE102004042894A1 (de) * | 2004-08-30 | 2006-03-02 | Eberhard-Karls-Universität Tübingen | Verwendung von Blockern der NKG2D-Rezeptor-/NKG2D-Liganden-Interaktion bei Autoimmunerkrankungen |
| CA2587572A1 (en) * | 2004-11-24 | 2006-06-01 | Schering Corporation | Dap-10 and uses thereof |
| WO2011130749A2 (en) | 2010-04-16 | 2011-10-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-hsv receptors |
| US20130156808A1 (en) * | 2011-11-22 | 2013-06-20 | Stipan Jonjic | Vaccine comprising beta-herpesvirus |
| JP6518199B6 (ja) | 2013-03-15 | 2019-06-12 | ノヴェロジックス・バイオテクノロジー,インコーポレーテッド | Micaおよびmicbタンパク質に対する抗体 |
| JP6588024B2 (ja) | 2013-10-28 | 2019-10-09 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | 腫瘍溶解性hsvベクター |
| BR112018015390A2 (pt) | 2016-01-27 | 2018-12-18 | Oncorus, Inc. | vetores virais oncolíticos e usos dos mesmos |
| WO2017218689A1 (en) | 2016-06-14 | 2017-12-21 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Expression of nkg2d activating ligand proteins for sensitizing cancer cells to attack by cytotoxic immune cells |
| WO2018006005A1 (en) | 2016-06-30 | 2018-01-04 | Oncorus, Inc. | Pseudotyped oncolytic viral delivery of therapeutic polypeptides |
| AU2017344411A1 (en) | 2016-10-19 | 2019-05-09 | Novelogics Biotechnology, Inc. | Antibodies to MICA and MICB proteins |
| WO2019023483A1 (en) | 2017-07-26 | 2019-01-31 | Oncorus, Inc. | ONCOLYTIC VIRAL VECTORS AND USES THEREOF |
| US11661447B2 (en) | 2017-08-03 | 2023-05-30 | The Cleveland Clinic Foundation | Human β2-glycoprotein I expression |
| US11865081B2 (en) | 2017-12-29 | 2024-01-09 | Virogin Biotech Canada Ltd. | Oncolytic viral delivery of therapeutic polypeptides |
| CN112285360B (zh) * | 2020-09-23 | 2023-08-22 | 台州市第一人民医院 | I-309在制备原发性干燥综合征诊断试剂或试剂盒中的应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US22239A (en) * | 1858-12-07 | Limekiln | ||
| US4311A (en) * | 1845-12-16 | William beebe | ||
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4965195A (en) | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US4968607A (en) | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
| WO1990005183A1 (en) | 1988-10-31 | 1990-05-17 | Immunex Corporation | Interleukin-4 receptors |
| WO1991018982A1 (en) | 1990-06-05 | 1991-12-12 | Immunex Corporation | Type ii interleukin-1 receptors |
| DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US20030004311A1 (en) | 1997-06-18 | 2003-01-02 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030022239A1 (en) | 1997-06-18 | 2003-01-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| ATE305510T1 (de) | 1997-12-17 | 2005-10-15 | Immunex Corp | Zelloberflächenglycoproteinen zusammenhang mit menschlicher b zell lymphomen - ulbp, dns und polypeptiden |
| DE69841110D1 (de) | 1997-12-17 | 2009-10-08 | Serono Genetics Inst Sa | Verlängerte cdns, die für sekretierte proteine kodieren |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| JP2003505082A (ja) | 1999-07-26 | 2003-02-12 | ジェネンテック・インコーポレーテッド | 新規なポリヌクレオチドとその使用法 |
| JP2004522404A (ja) | 1999-12-01 | 2004-07-29 | ジェネンテック・インコーポレーテッド | 分泌及び膜貫通ポリペプチドとそれをコードしている核酸 |
| AU2404001A (en) | 2000-01-06 | 2001-07-16 | Protegene Inc. | Human proteins having hydrophobic domains and dnas encoding these proteins |
| US20040219521A1 (en) * | 2000-01-21 | 2004-11-04 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| IL151873A0 (en) | 2000-03-24 | 2003-04-10 | Micromet Ag | Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex |
| WO2001083545A1 (fr) * | 2000-04-27 | 2001-11-08 | Takeda Chemical Industries, Ltd. | Nouvelle proteine et son utilisation |
| AU5943201A (en) | 2000-05-03 | 2001-11-12 | Amgen Inc | Modified peptides as therapeutic agents |
| WO2002068615A2 (en) | 2001-02-28 | 2002-09-06 | Fred Hutchinson Cancer Research Center, Inc. | Activation of lymphocyte populations expressing nkg2d using anti-nkg2d antibodies and ligand derivatives |
| US6821522B2 (en) * | 2001-05-31 | 2004-11-23 | The Regents Of The University Of California | Tumor Therapy |
| JP2005502335A (ja) * | 2001-08-08 | 2005-01-27 | インサイト・ゲノミックス・インコーポレイテッド | 細胞成長、分化および細胞死関連タンパク質 |
| WO2003054152A2 (en) * | 2001-12-10 | 2003-07-03 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
| AU2002238359A1 (en) * | 2002-03-04 | 2003-09-16 | Shanghai Genomics, Inc. | Tumor tag and the use thereof |
| AU2003270063A1 (en) * | 2002-09-04 | 2004-03-29 | The Trustees Of The University Of Pennsylvania | Immune cell receptor ligand and immune cell receptor |
-
2002
- 2002-10-04 MX MXPA04003057A patent/MXPA04003057A/es unknown
- 2002-10-04 CA CA002462790A patent/CA2462790A1/en not_active Abandoned
- 2002-10-04 WO PCT/US2002/031994 patent/WO2003029436A2/en not_active Ceased
- 2002-10-04 AT AT02778459T patent/ATE434624T1/de not_active IP Right Cessation
- 2002-10-04 DE DE60232742T patent/DE60232742D1/de not_active Expired - Lifetime
- 2002-10-04 EP EP02778459A patent/EP1451333B1/en not_active Expired - Lifetime
- 2002-10-04 AU AU2002340118A patent/AU2002340118B2/en not_active Ceased
- 2002-10-04 JP JP2003532654A patent/JP2005523681A/ja active Pending
- 2002-10-04 PL PL02373594A patent/PL373594A1/xx unknown
- 2002-10-04 US US10/265,811 patent/US7563450B2/en not_active Expired - Fee Related
-
2009
- 2009-06-05 US US12/479,543 patent/US8129167B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090274699A1 (en) | 2009-11-05 |
| WO2003029436A3 (en) | 2003-11-13 |
| US7563450B2 (en) | 2009-07-21 |
| JP2005523681A (ja) | 2005-08-11 |
| AU2002340118B2 (en) | 2007-09-13 |
| ATE434624T1 (de) | 2009-07-15 |
| WO2003029436A2 (en) | 2003-04-10 |
| MXPA04003057A (es) | 2005-06-20 |
| EP1451333A2 (en) | 2004-09-01 |
| CA2462790A1 (en) | 2003-04-10 |
| PL373594A1 (en) | 2005-09-05 |
| US8129167B2 (en) | 2012-03-06 |
| EP1451333B1 (en) | 2009-06-24 |
| EP1451333A4 (en) | 2005-03-30 |
| US20030195337A1 (en) | 2003-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |