DE60232585D1 - Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus - Google Patents

Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus

Info

Publication number
DE60232585D1
DE60232585D1 DE60232585T DE60232585T DE60232585D1 DE 60232585 D1 DE60232585 D1 DE 60232585D1 DE 60232585 T DE60232585 T DE 60232585T DE 60232585 T DE60232585 T DE 60232585T DE 60232585 D1 DE60232585 D1 DE 60232585D1
Authority
DE
Germany
Prior art keywords
expansion
development
cell types
haematopoietic
progenitor cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60232585T
Other languages
English (en)
Inventor
Dolores Baksh
John E Davies
Peter Zandstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60232585D1 publication Critical patent/DE60232585D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
DE60232585T 2001-04-24 2002-04-23 Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus Expired - Lifetime DE60232585D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28570101P 2001-04-24 2001-04-24
US32811001P 2001-10-11 2001-10-11
PCT/CA2002/000550 WO2002086104A1 (en) 2001-04-24 2002-04-23 Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom

Publications (1)

Publication Number Publication Date
DE60232585D1 true DE60232585D1 (de) 2009-07-23

Family

ID=26963332

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60232585T Expired - Lifetime DE60232585D1 (de) 2001-04-24 2002-04-23 Vorläuferzellpopulationen, deren expansion und die entstehung von nicht-hämatopoetischen zelltypen daraus

Country Status (9)

Country Link
US (2) US20040137612A1 (de)
EP (2) EP1383869B1 (de)
JP (1) JP2004531256A (de)
AT (1) ATE433484T1 (de)
CA (2) CA2843001A1 (de)
DE (1) DE60232585D1 (de)
DK (2) DK1383869T3 (de)
ES (1) ES2328460T3 (de)
WO (1) WO2002086104A1 (de)

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US7807458B2 (en) 2003-01-30 2010-10-05 The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs Multilineage-inducible cells and uses thereof
DE602004028803D1 (de) 2003-02-11 2010-10-07 John E Davies Vorläuferzellen aus der wharton sulze von humanen nabelschnüren
JP2006524092A (ja) * 2003-04-24 2006-10-26 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ 非侵襲性左心室容積決定
JP4604238B2 (ja) * 2003-09-19 2011-01-05 独立行政法人産業技術総合研究所 燐酸カルシウムと生理活性物質を含有する高分子複合体、その製造方法及びそれを用いた医療用材料
DK1725656T3 (da) * 2004-03-05 2014-01-13 John E Davies Serumfri suspensionskultursystem til mesenchymale progenitorceller
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
CN101080486B (zh) * 2004-04-23 2012-05-16 佰欧益股份有限公司 多谱系祖细胞
ES2417065T3 (es) 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
WO2007022348A2 (en) * 2005-08-18 2007-02-22 Massachusetts Institute Of Technology Amplification of cell polulations from embryonic stem cells
EP1962719A4 (de) 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd Medien zur züchtung von stammzellen
JP2009520466A (ja) 2005-12-22 2009-05-28 エニス，ジエーン 凍結臍帯組織由来の生存可能な細胞
ITTO20060282A1 (it) * 2006-04-14 2007-10-15 Univ Degli Studi Torino Mezzo di coltura e composizione farmaceutica per la rigenerazione del tessuto cartilagineo relativo procedimento relativi usi e prodotti
EP2019858B1 (de) * 2006-04-17 2012-06-13 BioE LLC Differenzierung von vorläuferzellen mit mehreren abstammungslinien in respiratorischen epithelzellen
WO2007128115A1 (en) * 2006-05-05 2007-11-15 Univ Toronto Immune privileged and modulatory progenitor cells
AU2007272313B2 (en) * 2006-07-12 2013-11-21 Mesoblast, Inc. Treatment of excessive neovascularization
ES2874223T3 (es) * 2006-08-02 2021-11-04 Technion Res & Dev Foundation Métodos de expansión de células madre embrionarias en un cultivo en suspensión
US20090029463A1 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of Multi-Lineage Progenitor Cells to Chondrocytes
JP2011512992A (ja) * 2008-03-03 2011-04-28 ウイリアム、マーシュ、ライス、ユーニヴァーサティ 改良された組織工学的に作製された軟骨を組み立てる方法
KR20170005148A (ko) 2008-04-21 2017-01-11 티슈 리제너레이션 쎄라퓨틱스, 인코포레이티드 생물학적 또는 화학적 물질에 대한 예방 또는 치료를 위한 유전적으로 변형된 인간 탯줄 혈관주위 세포
US20110104126A1 (en) * 2008-05-14 2011-05-05 Public University Corporation Yokohama City Univer Human Hepatic Stem Cell, Method for Preparation of the Same, Method for Induction of Differentiation of the Same, and Method for Utilization of the Same
CA2724839A1 (en) * 2008-05-21 2009-11-26 Bioe Llc Differentiation of multi-lineage progenitor cells to pancreatic cells
SG10201503700WA (en) 2010-05-12 2015-06-29 Abt Holding Co Modulation of splenocytes in cell therapy
EP2625267A2 (de) 2010-10-06 2013-08-14 Omnicyte Ltd. Kulturverfahren zur kultivierung pluripotenter zellen mit einem mirna-181a*-inhibitor
EP2625264B1 (de) 2010-10-08 2022-12-07 Terumo BCT, Inc. Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
HUE052516T2 (hu) 2013-04-12 2021-05-28 Houston Methodist Hospital Szervek javítása transzplantációhoz
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
EP3242692A4 (de) * 2015-01-05 2018-09-05 Histogenics Corporation Neoknorpelkonstrukte mit universellen zellen
EP3098304A1 (de) 2015-05-28 2016-11-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Hybrides zellenablösungsfreies zellenerweiterungssystem für anklebende zellkultivierung und zugehöriges verfahrensprotokoll
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
AU2016387339B2 (en) 2016-01-21 2022-11-17 Abt Holding Company Stem cells for wound healing
KR102557574B1 (ko) * 2016-05-17 2023-07-20 엘지전자 주식회사 디지털 디바이스 및 그 제어 방법
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2020061408A1 (en) * 2018-09-21 2020-03-26 Tarachon Llc Cartilage regeneration by synovial fluid-derived stem cells and their derivatives

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US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6010696A (en) * 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US7514074B2 (en) * 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
JP2002507407A (ja) * 1998-03-23 2002-03-12 ザイモジェネティクス，インコーポレイティド 心臓由来幹細胞
IL142914A0 (en) 1998-11-09 2002-04-21 Consorzio Per La Gestione Del Serum free medium for chondrocyte-like cells
IL147990A0 (en) * 1999-08-05 2002-09-12 Mcl Llc Multipotent adult stem cells and methods for isolation
US20040137612A1 (en) 2001-04-24 2004-07-15 Dolores Baksh Progenitor cell populations , expansions thereof, and growth of non-hematopoietic cell types and tissues therefrom
KR100534215B1 (ko) 2003-11-11 2005-12-08 (주)히스토스템 냉동 보관된 제대혈로부터 중간엽 줄기세포의 분리 및 배양 방법

Also Published As

Publication number Publication date
JP2004531256A (ja) 2004-10-14
CA2843001A1 (en) 2002-10-31
EP2105497A1 (de) 2009-09-30
ATE433484T1 (de) 2009-06-15
DK1383869T3 (da) 2009-10-05
US9644182B2 (en) 2017-05-09
WO2002086104A1 (en) 2002-10-31
CA2444959C (en) 2014-07-08
US20040137612A1 (en) 2004-07-15
CA2444959A1 (en) 2002-10-31
EP1383869A1 (de) 2004-01-28
EP2105497B1 (de) 2019-04-03
DK2105497T3 (da) 2019-06-24
EP1383869B1 (de) 2009-06-10
US20080020459A1 (en) 2008-01-24
ES2328460T3 (es) 2009-11-13

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