DE60230990D1 - Zellkulturmethode zur erzeugung von prostata-ähnlichen acini - Google Patents

Zellkulturmethode zur erzeugung von prostata-ähnlichen acini

Info

Publication number
DE60230990D1
DE60230990D1 DE60230990T DE60230990T DE60230990D1 DE 60230990 D1 DE60230990 D1 DE 60230990D1 DE 60230990 T DE60230990 T DE 60230990T DE 60230990 T DE60230990 T DE 60230990T DE 60230990 D1 DE60230990 D1 DE 60230990D1
Authority
DE
Germany
Prior art keywords
acini
prostate
cell culture
culture method
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230990T
Other languages
English (en)
Inventor
Shona Lang
Norman Maitland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procure Therapeutics Ltd
Original Assignee
Procure Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0119533A external-priority patent/GB0119533D0/en
Application filed by Procure Therapeutics Ltd filed Critical Procure Therapeutics Ltd
Application granted granted Critical
Publication of DE60230990D1 publication Critical patent/DE60230990D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0683—Cells of the male genital tract, e.g. prostate, epididymis; Non-germinal cells from testis, e.g. Leydig cells, Sertoli cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C12N2501/392—Sexual steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
DE60230990T 2001-08-09 2002-08-09 Zellkulturmethode zur erzeugung von prostata-ähnlichen acini Expired - Lifetime DE60230990D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31120201P 2001-08-09 2001-08-09
GB0119533A GB0119533D0 (en) 2001-08-10 2001-08-10 Cell differentiation
PCT/GB2002/003675 WO2003014334A1 (en) 2001-08-09 2002-08-09 Cell culture method for obtaining prostate-like acini

Publications (1)

Publication Number Publication Date
DE60230990D1 true DE60230990D1 (de) 2009-03-12

Family

ID=26246428

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230990T Expired - Lifetime DE60230990D1 (de) 2001-08-09 2002-08-09 Zellkulturmethode zur erzeugung von prostata-ähnlichen acini

Country Status (7)

Country Link
US (1) US20050003527A1 (de)
EP (1) EP1414945B8 (de)
JP (1) JP2004537999A (de)
AT (1) ATE421574T1 (de)
DE (1) DE60230990D1 (de)
GB (1) GB2393735B (de)
WO (1) WO2003014334A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005071400A2 (en) * 2004-01-26 2005-08-04 Procure Therapeutics Limited Screening model
GB0406215D0 (en) 2004-03-19 2004-04-21 Procure Therapeutics Ltd Prostate stem cell
GB0625041D0 (en) * 2006-12-15 2007-01-24 Procure Therapeutics Ltd Prostate stem cell model
EP2625264B1 (de) 2010-10-08 2022-12-07 Terumo BCT, Inc. Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
GB201213654D0 (en) 2012-08-01 2012-09-12 Univ Singapore Cell culture
WO2014082096A1 (en) 2012-11-26 2014-05-30 The Trustees Of Columbia University In The City Of New York Method for culture of human and mouse prostate organoids and uses thereof
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117050934B (zh) * 2023-10-11 2024-01-30 四川大学华西医院 小鼠前列腺类器官制备方法及原发原位前列腺癌动物模型

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824488A (en) * 1994-04-28 1998-10-20 Board Of Trustees Operating Michigan State University Immortalized and malignant human prostatic cell lines

Also Published As

Publication number Publication date
EP1414945B1 (de) 2009-01-21
GB2393735A (en) 2004-04-07
EP1414945A1 (de) 2004-05-06
GB0401201D0 (en) 2004-02-25
EP1414945B8 (de) 2009-04-01
JP2004537999A (ja) 2004-12-24
US20050003527A1 (en) 2005-01-06
ATE421574T1 (de) 2009-02-15
WO2003014334A1 (en) 2003-02-20
GB2393735B (en) 2006-01-18

Similar Documents

Publication Publication Date Title
DE60230990D1 (de) Zellkulturmethode zur erzeugung von prostata-ähnlichen acini
DE60025015D1 (de) Verfahren zur herstellung von rekombinanten proteinen mittels inhibitoren von apoptose
TR199900781T2 (xx) H�cre yap��ma inhibit�rleri
SG129236A1 (en) Somatic pluripotent cells
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
DE69928697D1 (de) Sulfohydroxamsäure and sulfohydroxamate und ihre verwendung als mek-inhibitoren
DE602005009852D1 (de) Verwendung von cannabidiol zur hemmung von gehirntumorzellmigration
DE60038951D1 (de) Verfahren zur inhibierung von gehirntumorwachstum durch verwendung von antagonisten von integrinen
ATE501126T1 (de) Verfahren zur herstellung von rosuvastatin
ATE340857T1 (de) Verfahren zur herstellung von l-aminosäuren durch erhöhung des zellulären nadph
ATE394124T1 (de) Verfahren, zusammensetzungen und herstellungsgegenstände zur modulierung des knochenwachstums
ATE510553T1 (de) Beta-2-glycoprotein 1 als angiogenesehemmer
ATE309353T1 (de) Verfahren zur herstellung von rekombinanten peptiden
DK1272457T3 (da) Forbindelser til modulation af celleproliferation
TW200506059A (en) Method for obtaining mastocyte lines from pig tissues and for producing heparin-type molecules
DE50211985D1 (de) Verwendung von pyridin-2,4-dicarbons urediamiden und pyrimid in-4,6-dicarbons urediamiden zur selektiven inhibierung von kollagenasen
ATE339208T1 (de) Verwendung von progesteronrezeptorhemmern zur behandlung von steroid-resistentem brustkrebs
DK1058739T3 (da) Fremgangsmåde til dannelse af genekspressionsprofiler
ATE385503T1 (de) Verfahren zur modulierung von integrin- vermittelter zellaktivitaet und hierfuer geeignete reagenzien
WO2002050301A3 (en) Gene expression profiles associated with osteoblast differentiation
ATE423129T1 (de) Inhibitoren von lyn-verbundener signaltransduktion (last) und deren verwendung zur behandlung von prostatakrebs
PT1276722E (pt) Inibidores de naftamidina-uroquinase
ATE480237T1 (de) Tumorhemmende nitroacridin-zusammensetzungen
EP1440085B8 (de) Transiente immortalisierung von zellen durch onkogenproteine oder telomerproteine
TWI266804B (en) Method of generating neurons from stem cells and medium for culturing stem cells

Legal Events

Date Code Title Description
8364 No opposition during term of opposition