DE60227178D1 - R herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration - Google Patents

R herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration

Info

Publication number
DE60227178D1
DE60227178D1 DE60227178T DE60227178T DE60227178D1 DE 60227178 D1 DE60227178 D1 DE 60227178D1 DE 60227178 T DE60227178 T DE 60227178T DE 60227178 T DE60227178 T DE 60227178T DE 60227178 D1 DE60227178 D1 DE 60227178D1
Authority
DE
Germany
Prior art keywords
negatively charged
makular
medicament
prevention
generation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60227178T
Other languages
English (en)
Inventor
Christoph Richter
Paolo Gazzotti
Hamdy Shaban
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LYNKEUS BIOTECH GmbH
Original Assignee
LYNKEUS BIOTECH GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LYNKEUS BIOTECH GmbH filed Critical LYNKEUS BIOTECH GmbH
Application granted granted Critical
Publication of DE60227178D1 publication Critical patent/DE60227178D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60227178T 2001-08-22 2002-07-01 R herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration Expired - Lifetime DE60227178D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10141018A DE10141018A1 (de) 2001-08-22 2001-08-22 Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
PCT/EP2002/007237 WO2003018028A1 (en) 2001-08-22 2002-07-01 Compositions comprising negatively charched phospholipids for treatment and/or prevention of macular degeneration and method for its manufacture

Publications (1)

Publication Number Publication Date
DE60227178D1 true DE60227178D1 (de) 2008-07-31

Family

ID=7696167

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10141018A Ceased DE10141018A1 (de) 2001-08-22 2001-08-22 Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
DE60227178T Expired - Lifetime DE60227178D1 (de) 2001-08-22 2002-07-01 R herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10141018A Ceased DE10141018A1 (de) 2001-08-22 2001-08-22 Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges

Country Status (7)

Country Link
US (1) US20030050283A1 (de)
EP (1) EP1418922B1 (de)
JP (1) JP2005501109A (de)
AT (1) ATE398456T1 (de)
CA (1) CA2458132A1 (de)
DE (2) DE10141018A1 (de)
WO (1) WO2003018028A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7470659B2 (en) * 2001-12-07 2008-12-30 The Regents Of The University Of California Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)
US8197851B2 (en) * 2004-09-29 2012-06-12 Michael Ary Bos Carotenoid composition and method for preparation thereof
US20060252107A1 (en) * 2005-02-22 2006-11-09 Acucela, Inc. Compositions and methods for diagnosing and treating retinal diseases
EP1922062A2 (de) * 2005-09-08 2008-05-21 DSMIP Assets B.V. Verfahren zur behandlung oder prävention von altersbedingter makula-degeneration
WO2007038549A1 (en) * 2005-09-26 2007-04-05 Vasogen Ireland Limited Treatment of inflammation and vascular abnormalities of the eye
US20070254832A1 (en) * 2006-02-17 2007-11-01 Pressler Milton L Methods for the treatment of macular degeneration and related eye conditions
WO2007096744A1 (en) * 2006-02-21 2007-08-30 Pfizer Products Inc. Methods for the treatment of macular degeneration and related eye conditions
CN101686665B (zh) 2007-04-20 2014-04-23 奥克塞拉有限公司 用于治疗眼科疾病和紊乱的苯乙烯基衍生化合物
BRPI0812755A2 (pt) 2007-06-29 2014-09-30 Acucela Inc Compostos de derivados de fenil alquinila para tratar doenças, e desordens oftálmicas
CN101889017B (zh) 2007-10-05 2013-11-27 奥克塞拉有限公司 用于治疗疾病的烷氧基化合物
US20090312438A1 (en) * 2008-06-13 2009-12-17 Bernstein Paul S Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium
EP2804605A4 (de) 2012-01-20 2015-07-08 Acucela Inc Substituierte heterocyclische verbindungen zur behandlung von krankheiten
EP2970099A4 (de) 2013-03-12 2016-12-21 Acucela Inc Substituierte 3-phenylpropylaminderivate zur behandlung von augenerkrankungen und -leiden
US10292943B2 (en) 2014-08-11 2019-05-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Delivery of bioactive, nanoencapsulated antioxidants

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
WO1990011781A1 (en) * 1989-04-04 1990-10-18 Alcon Laboratories, Inc. The use of liposomes for the delivery of therapeutic agents to wounds, cuts and abrasions
ES2084722T3 (es) * 1990-05-29 1996-05-16 Boston Ocular Res Composicion para tratamiento del ojo seco.
EP0531933B1 (de) * 1991-09-09 1997-07-09 Canon Kabushiki Kaisha Quantitativer Nachweis vom Lipid
AU719671B2 (en) * 1995-06-07 2000-05-18 Howard Foundation, The Pharmaceutically active carotenoids
US6075058A (en) * 1998-12-12 2000-06-13 Tufts University Compositions for increased bioavailability of carotenoids

Also Published As

Publication number Publication date
CA2458132A1 (en) 2003-03-06
EP1418922A1 (de) 2004-05-19
EP1418922B1 (de) 2008-06-18
JP2005501109A (ja) 2005-01-13
WO2003018028A1 (en) 2003-03-06
DE10141018A1 (de) 2003-03-13
ATE398456T1 (de) 2008-07-15
US20030050283A1 (en) 2003-03-13

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Legal Events

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8364 No opposition during term of opposition