DE60223524D1 - Verfahren zur vorbeugung von zelltod unter verwendung von antikörpern gegen neural thread proteine - Google Patents

Verfahren zur vorbeugung von zelltod unter verwendung von antikörpern gegen neural thread proteine

Info

Publication number
DE60223524D1
DE60223524D1 DE60223524T DE60223524T DE60223524D1 DE 60223524 D1 DE60223524 D1 DE 60223524D1 DE 60223524 T DE60223524 T DE 60223524T DE 60223524 T DE60223524 T DE 60223524T DE 60223524 D1 DE60223524 D1 DE 60223524D1
Authority
DE
Germany
Prior art keywords
antibody
ntp
deod
antibodies
cell death
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60223524T
Other languages
English (en)
Inventor
Paul A Averback
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nymox Corp Canada
Nymox Corp
Original Assignee
Nymox Corp Canada
Nymox Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nymox Corp Canada, Nymox Corp filed Critical Nymox Corp Canada
Application granted granted Critical
Publication of DE60223524D1 publication Critical patent/DE60223524D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60223524T 2001-05-04 2002-05-06 Verfahren zur vorbeugung von zelltod unter verwendung von antikörpern gegen neural thread proteine Expired - Lifetime DE60223524D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28846301P 2001-05-04 2001-05-04
PCT/CA2002/000681 WO2002089841A2 (en) 2001-05-04 2002-05-06 Method of preventing cell death using antibodies to neural thread proteins

Publications (1)

Publication Number Publication Date
DE60223524D1 true DE60223524D1 (de) 2007-12-27

Family

ID=23107207

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223524T Expired - Lifetime DE60223524D1 (de) 2001-05-04 2002-05-06 Verfahren zur vorbeugung von zelltod unter verwendung von antikörpern gegen neural thread proteine

Country Status (10)

Country Link
US (1) US20030003445A1 (de)
EP (1) EP1387698B1 (de)
JP (1) JP2004528367A (de)
KR (1) KR20040029968A (de)
CN (1) CN1635906A (de)
AT (1) ATE378069T1 (de)
AU (1) AU2002308327B2 (de)
CA (1) CA2446480A1 (de)
DE (1) DE60223524D1 (de)
WO (1) WO2002089841A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160361380A1 (en) * 2015-06-12 2016-12-15 Nymox Corporation Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880816A (en) * 1982-05-18 1989-11-14 University Of Florida Brain-specific delivery of dopamine utilizing dihydropyridine/pyridinium salt-type redox carriers
US5187158A (en) * 1982-05-18 1993-02-16 University Of Florida Brain-specific drug delivery
US5017566A (en) * 1987-12-30 1991-05-21 University Of Florida Redox systems for brain-targeted drug delivery
ES2094733T3 (es) * 1988-12-21 1997-02-01 Gen Hospital Corp Deteccion de enfermedades o disfunciones neurologicas.
US5948634A (en) * 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
EP0975651A4 (de) * 1997-02-26 2005-03-09 Gen Hospital Corp Transgene tiere und zellinien zur erkennung von zur behandlung oder vorbeugung der alzheimerschen krankheit wirksamen medikamente
WO1999000150A2 (en) * 1997-06-27 1999-01-07 Regents Of The University Of California Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
KR100632903B1 (ko) * 2001-03-08 2006-10-13 니목스 파마슈티칼스 코포레이션 신경 사 단백질을 사용하여 종양 및 세포의 제거 또는파괴를 필요로 하는 다른 증상을 치료하는 방법
US6770797B2 (en) * 2001-06-01 2004-08-03 Rhode Island Hospital Non-Transgenic nonhuman model for Alzheimer's Disease using a AD7c-NTP nucleic acid

Also Published As

Publication number Publication date
JP2004528367A (ja) 2004-09-16
US20030003445A1 (en) 2003-01-02
CA2446480A1 (en) 2002-11-14
KR20040029968A (ko) 2004-04-08
AU2002308327B2 (en) 2006-11-30
ATE378069T1 (de) 2007-11-15
CN1635906A (zh) 2005-07-06
EP1387698B1 (de) 2007-11-14
WO2002089841A3 (en) 2003-04-24
EP1387698A2 (de) 2004-02-11
WO2002089841A2 (en) 2002-11-14

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DE60223524D1 (de) Verfahren zur vorbeugung von zelltod unter verwendung von antikörpern gegen neural thread proteine
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EA199901043A1 (ru) ИНГИБИТОРЫ ФАРНЕЗИЛТРАНСФЕРАЗЫ В КОМБИНАЦИИ С ИНГИБИТОРАМИ HMG-CoA-РЕДУКТАЗЫ ДЛЯ ЛЕЧЕНИЯ РАКА

Legal Events

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