DE60223290D1 - Hemmer des komplex ii des elektronentransportsystems - Google Patents

Hemmer des komplex ii des elektronentransportsystems

Info

Publication number
DE60223290D1
DE60223290D1 DE60223290T DE60223290T DE60223290D1 DE 60223290 D1 DE60223290 D1 DE 60223290D1 DE 60223290 T DE60223290 T DE 60223290T DE 60223290 T DE60223290 T DE 60223290T DE 60223290 D1 DE60223290 D1 DE 60223290D1
Authority
DE
Germany
Prior art keywords
hammer
complex
electron transport
transport system
electron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60223290T
Other languages
English (en)
Inventor
Satoshi Omura
Kazuro Shiomi
Hiroshi Tomoda
Rokuro Masuma
Kiyoshi Kita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Application granted granted Critical
Publication of DE60223290D1 publication Critical patent/DE60223290D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/80Penicillium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60223290T 2002-06-10 2002-06-10 Hemmer des komplex ii des elektronentransportsystems Expired - Lifetime DE60223290D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2002/005727 WO2003103667A1 (ja) 2002-06-10 2002-06-10 電子伝達系の複合体ii阻害剤

Publications (1)

Publication Number Publication Date
DE60223290D1 true DE60223290D1 (de) 2007-12-13

Family

ID=29727331

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223290T Expired - Lifetime DE60223290D1 (de) 2002-06-10 2002-06-10 Hemmer des komplex ii des elektronentransportsystems

Country Status (6)

Country Link
US (1) US7514455B2 (de)
EP (1) EP1512402B1 (de)
JP (1) JP4334472B2 (de)
AU (1) AU2002306342A1 (de)
DE (1) DE60223290D1 (de)
WO (1) WO2003103667A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2063884B1 (de) * 2006-09-15 2014-08-13 Stephen John Ralph Pro-oxidative verbindungen gegen krebs
WO2010069495A1 (de) * 2008-12-18 2010-06-24 Bayer Cropscience Aktiengesellschaft Atpenine
JP5963278B2 (ja) * 2014-12-24 2016-08-03 学校法人北里研究所 種選択的な電子伝達系の複合体ii阻害活性を有する新規アトペニン類縁体
BR112018067628A2 (pt) 2016-03-09 2018-12-26 Nippon Soda Co., Ltd. composto de piridina, fungicida agrícola e hortícola, agente de controle de organismo nocivo, agente inseticida ou acaricida, e, agente de controle de ectoparasita

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50132183A (de) * 1974-03-19 1975-10-20
JPH01199582A (ja) * 1988-02-05 1989-08-10 Kitasato Inst:The 新規抗生物質fo−125a↓4、a↓5、bおよびそれらの製造法
US5313332A (en) * 1990-11-16 1994-05-17 Applied Magnetics Corporation Flexure suspension for two axis actuator
JP2503836B2 (ja) * 1992-06-08 1996-06-05 株式会社神戸製鋼所 ヒト腫瘍細胞に対する選択的細胞障害剤

Also Published As

Publication number Publication date
AU2002306342A1 (en) 2003-12-22
EP1512402B1 (de) 2007-10-31
JP4334472B2 (ja) 2009-09-30
US7514455B2 (en) 2009-04-07
EP1512402A4 (de) 2005-07-13
US20040266835A1 (en) 2004-12-30
WO2003103667A1 (ja) 2003-12-18
JPWO2003103667A1 (ja) 2005-10-06
EP1512402A1 (de) 2005-03-09

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Legal Events

Date Code Title Description
8332 No legal effect for de