DE60220921D1 - Vorrichtung zur elektrophoretischen trennung auf mikrokanälen und zum laserinduzierten fluoreszenznachweis - Google Patents

Vorrichtung zur elektrophoretischen trennung auf mikrokanälen und zum laserinduzierten fluoreszenznachweis

Info

Publication number
DE60220921D1
DE60220921D1 DE60220921T DE60220921T DE60220921D1 DE 60220921 D1 DE60220921 D1 DE 60220921D1 DE 60220921 T DE60220921 T DE 60220921T DE 60220921 T DE60220921 T DE 60220921T DE 60220921 D1 DE60220921 D1 DE 60220921D1
Authority
DE
Germany
Prior art keywords
laser
electrophoretic separation
fluorescent detection
micro channels
induced fluorescent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60220921T
Other languages
English (en)
Other versions
DE60220921T2 (de
Inventor
Francois Couderc
Michel Nertz
Bernard Feurer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Picometrics SA
Original Assignee
Picometrics SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picometrics SA filed Critical Picometrics SA
Publication of DE60220921D1 publication Critical patent/DE60220921D1/de
Application granted granted Critical
Publication of DE60220921T2 publication Critical patent/DE60220921T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G01N2030/746—Optical detectors detecting along the line of flow, e.g. axial
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE60220921T 2001-07-25 2002-07-22 Vorrichtung zur elektrophoretischen trennung auf mikrokanälen und zum laserinduzierten fluoreszenznachweis Expired - Lifetime DE60220921T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0109955 2001-07-25
FR0109955A FR2827957B1 (fr) 2001-07-25 2001-07-25 Appareil de separation par electrophorese sur veine liquide et de detection par fluorescence induite par laser
PCT/FR2002/002612 WO2003010522A1 (fr) 2001-07-25 2002-07-22 Appareil de separation par electrophorese sur microcanaux et de detection par fluorescence induite par laser

Publications (2)

Publication Number Publication Date
DE60220921D1 true DE60220921D1 (de) 2007-08-09
DE60220921T2 DE60220921T2 (de) 2008-02-28

Family

ID=8865900

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60220921T Expired - Lifetime DE60220921T2 (de) 2001-07-25 2002-07-22 Vorrichtung zur elektrophoretischen trennung auf mikrokanälen und zum laserinduzierten fluoreszenznachweis

Country Status (5)

Country Link
US (1) US20050000812A1 (de)
EP (1) EP1409999B1 (de)
DE (1) DE60220921T2 (de)
FR (1) FR2827957B1 (de)
WO (1) WO2003010522A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1586893A1 (de) * 2005-02-16 2005-10-19 Agilent Technologies Inc Mikrofluidische Vorrichtung mit Formanpassung der Probe
US7846390B2 (en) * 2006-03-30 2010-12-07 King Fahd University Of Petroleum And Minerals Apparatus and method for measuring concentrations of fuel mixtures using depth-resolved laser-induced fluorescence
JP6755188B2 (ja) * 2014-03-07 2020-09-16 ライフ テクノロジーズ コーポレーション キャピラリー電気泳動のための光学システム
WO2015134943A1 (en) 2014-03-07 2015-09-11 Life Technologies Corporation Capillary array cartridge for capillary electrophoresis systems
US10028720B2 (en) * 2014-10-07 2018-07-24 Carestream Health, Inc. Quality control phantom
CN105760810B (zh) * 2015-02-10 2021-11-19 公安部第一研究所 透射式三维指静脉数据采集装置
WO2017065163A1 (ja) 2015-10-14 2017-04-20 アルプス電気株式会社 流路構造体および測定対象液体の測定装置
CN107576639A (zh) * 2017-08-28 2018-01-12 博奥生物集团有限公司 便携式全集成dna现场检验微型全分析系统检测光路

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0341928A1 (de) * 1988-05-10 1989-11-15 AMERSHAM INTERNATIONAL plc Oberflächen-Resonanzplasmawellen-Sensoren
US4908112A (en) * 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
US4960999A (en) * 1989-02-13 1990-10-02 Kms Fusion, Inc. Scanning and storage of electrophoretic records
US5062942A (en) * 1989-04-12 1991-11-05 Hitachi, Ltd. Fluorescence detection type electrophoresis apparatus
DE59104604D1 (de) * 1990-11-26 1995-03-23 Ciba Geigy Ag Detektorzelle.
US6454945B1 (en) * 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US6008055A (en) * 1998-06-30 1999-12-28 Transgenomic, Inc. Modular component fiber optic fluorescence detector system, and method of use
US6454925B1 (en) * 1997-08-25 2002-09-24 Shimadzu Corporation Device for electrophoresis and component therefor
JP2001518624A (ja) * 1997-09-26 2001-10-16 ユニバーシティ・オブ・ワシントン 同時の粒子分離および化学反応
FR2774472B1 (fr) * 1998-01-30 2000-04-21 Centre Nat Rech Scient Perfectionnements aux systemes d'electrophorese multicapillaire
US6224830B1 (en) * 1998-01-30 2001-05-01 The Governors Of The University Of Alberta Absorbance cell for microfluid devices
DE19817738C2 (de) * 1998-04-21 2003-02-06 Karl-Friedrich Klein Hohle optische Wellenleiter für die Spurenanalyse in wässrigen Lösungen
SE9802558D0 (sv) * 1998-07-16 1998-07-16 Hanning Instr Ab Device for detection of fluorescent
US6906797B1 (en) * 1999-09-13 2005-06-14 Aclara Biosciences, Inc. Side light activated microfluid channels
US6942773B1 (en) * 2001-01-26 2005-09-13 The Regents Of The University Of California Particle sizer and DNA sequencer
US6596140B2 (en) * 2001-05-01 2003-07-22 Applera Corporation Multi-channel capillary electrophoresis device and method
US6731437B2 (en) * 2001-05-04 2004-05-04 Applera Corporation Energy beam guide for an electrophoresis system
FR2827958B1 (fr) * 2001-07-25 2003-09-26 Picometrics Dispositif d'analyse par fluorescence induite par laser et appareil de separation avec un tel dispositif

Also Published As

Publication number Publication date
US20050000812A1 (en) 2005-01-06
EP1409999A1 (de) 2004-04-21
FR2827957A1 (fr) 2003-01-31
FR2827957B1 (fr) 2003-09-26
EP1409999B1 (de) 2007-06-27
WO2003010522A1 (fr) 2003-02-06
DE60220921T2 (de) 2008-02-28

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