DE60210254D1 - Aminosubstituierter hypocrelline zur verwendung als sonosensitizer - Google Patents

Aminosubstituierter hypocrelline zur verwendung als sonosensitizer

Info

Publication number
DE60210254D1
DE60210254D1 DE60210254T DE60210254T DE60210254D1 DE 60210254 D1 DE60210254 D1 DE 60210254D1 DE 60210254 T DE60210254 T DE 60210254T DE 60210254 T DE60210254 T DE 60210254T DE 60210254 D1 DE60210254 D1 DE 60210254D1
Authority
DE
Germany
Prior art keywords
hypocrelline
sonosensitizer
amino
substituted
substituted hypocrelline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60210254T
Other languages
English (en)
Inventor
G Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quest Pharmatech Inc
Original Assignee
Altachem Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altachem Pharma Ltd filed Critical Altachem Pharma Ltd
Application granted granted Critical
Publication of DE60210254D1 publication Critical patent/DE60210254D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A61K41/0033—Sonodynamic cancer therapy with sonochemically active agents or sonosensitizers, having their cytotoxic effects enhanced through application of ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60210254T 2002-01-29 2002-01-29 Aminosubstituierter hypocrelline zur verwendung als sonosensitizer Expired - Lifetime DE60210254D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2002/000268 WO2003063901A1 (en) 2002-01-29 2002-01-29 Amino-substituted hypocrellins for use as sonosensitizers

Publications (1)

Publication Number Publication Date
DE60210254D1 true DE60210254D1 (de) 2006-05-18

Family

ID=27637598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60210254T Expired - Lifetime DE60210254D1 (de) 2002-01-29 2002-01-29 Aminosubstituierter hypocrelline zur verwendung als sonosensitizer

Country Status (4)

Country Link
US (1) US20050143406A1 (de)
EP (1) EP1476190B1 (de)
DE (1) DE60210254D1 (de)
WO (1) WO2003063901A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1349965A (zh) * 2000-10-25 2002-05-22 中国科学院感光化学研究所 带有脂肪环或芳香环的脂肪胺基取代去甲氧基竹红菌素及其合成方法和用途
US7816563B1 (en) * 2009-12-08 2010-10-19 Alberta Innovates-Technology Futures Method for preparing hypocrellin
CA3002695C (en) 2015-10-21 2020-12-22 Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences Monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof
CN105541647A (zh) * 2015-10-21 2016-05-04 中国科学院理化技术研究所 含长链季铵盐的竹红菌素衍生物及其制备方法和应用
WO2017067497A2 (zh) * 2015-10-21 2017-04-27 中国科学院理化技术研究所 一种单取代或多取代的酯水双亲性竹红菌素衍生物及其制备方法和应用
CN111825624B (zh) * 2016-10-13 2021-07-27 中国科学院理化技术研究所 酯水双亲性竹红菌素衍生物及其制备方法和应用
CN109422640A (zh) * 2017-08-25 2019-03-05 中国科学院化学研究所 竹红菌素衍生物及其制备方法与应用
CN116135831A (zh) * 2021-11-18 2023-05-19 中国科学院理化技术研究所 一种竹红菌素的2-位聚乙二醇取代的水溶性衍生物及其在治疗肿瘤中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9710049D0 (en) * 1997-05-19 1997-07-09 Nycomed Imaging As Method
IL120891A0 (en) * 1997-05-22 1997-09-30 Technion Res & Dev Foundation Photodynamic and sonodynamic therapy and agents for use therefor
AU4859699A (en) * 1998-07-06 2000-01-24 Pharmacyclics, Inc. Intracellular sensitizers for sonodynamic therapy
CN1349965A (zh) * 2000-10-25 2002-05-22 中国科学院感光化学研究所 带有脂肪环或芳香环的脂肪胺基取代去甲氧基竹红菌素及其合成方法和用途
CA2450370A1 (en) * 2001-06-11 2002-12-19 Jody Mesaros Accelerators for increasing the rate of formation of free radicals and reactive oxygen species

Also Published As

Publication number Publication date
EP1476190B1 (de) 2006-03-29
US20050143406A1 (en) 2005-06-30
WO2003063901A1 (en) 2003-08-07
EP1476190A1 (de) 2004-11-17

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Legal Events

Date Code Title Description
8332 No legal effect for de