DE60207913D1 - Als Matrix-Metalloproteinasehemmer verwendbare tricyclische Sulfonamide - Google Patents
Als Matrix-Metalloproteinasehemmer verwendbare tricyclische SulfonamideInfo
- Publication number
- DE60207913D1 DE60207913D1 DE60207913T DE60207913T DE60207913D1 DE 60207913 D1 DE60207913 D1 DE 60207913D1 DE 60207913 T DE60207913 T DE 60207913T DE 60207913 T DE60207913 T DE 60207913T DE 60207913 D1 DE60207913 D1 DE 60207913D1
- Authority
- DE
- Germany
- Prior art keywords
- matrix metalloproteinase
- metalloproteinase inhibitors
- alkyl
- tricyclic
- sulfonamides useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26873701P | 2001-02-14 | 2001-02-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60207913D1 true DE60207913D1 (de) | 2006-01-19 |
Family
ID=23024247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60207913T Expired - Lifetime DE60207913D1 (de) | 2001-02-14 | 2002-02-08 | Als Matrix-Metalloproteinasehemmer verwendbare tricyclische Sulfonamide |
Country Status (8)
Country | Link |
---|---|
US (1) | US6559142B2 (de) |
EP (1) | EP1233017B1 (de) |
JP (1) | JP2002308859A (de) |
AT (1) | ATE312829T1 (de) |
BR (1) | BR0200414A (de) |
CA (1) | CA2371481A1 (de) |
DE (1) | DE60207913D1 (de) |
MX (1) | MXPA01013172A (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
ES2537514T3 (es) | 2003-04-04 | 2015-06-09 | Incyte Corporation | Composiciones, métodos y kits relacionados con la escisión de HER-2 |
EP2074107A2 (de) * | 2006-10-27 | 2009-07-01 | Wyeth a Corporation of the State of Delaware | Trizyklische verbindungen als matrix-metalloprotease-hemmer |
DK2099442T3 (en) * | 2006-12-26 | 2015-02-16 | Pharmacyclics Inc | Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy |
CL2008001257A1 (es) * | 2007-05-04 | 2008-07-04 | Wyeth Corp | Compuestos triciclicos, inhibidores de metaloproteinasas matriciales; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como artritis reumatoide, osteoartritis, aterosclerosis, cancer de pulmon, entre otras. |
US9492423B2 (en) | 2011-09-13 | 2016-11-15 | Pharmacyclics Llc | Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1131215C (zh) | 1995-11-13 | 2003-12-17 | 赫彻斯特股份公司 | 环和杂环N-取代的α-亚氨基异羟肟酸和羧酸 |
AU735013B2 (en) * | 1996-09-04 | 2001-06-28 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
US6008243A (en) | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
IL128545A0 (en) | 1996-12-09 | 2000-01-31 | Warner Lambert Co | Method for treating and preventing heart failure and ventricular dilatation |
AU722784B2 (en) | 1997-02-11 | 2000-08-10 | Pfizer Inc. | Arylsulfonyl hydroxamic acid derivatives |
US6934639B1 (en) | 2000-02-25 | 2005-08-23 | Wyeth | Methods for designing agents that interact with MMP-13 |
-
2001
- 2001-12-18 MX MXPA01013172A patent/MXPA01013172A/es active IP Right Grant
-
2002
- 2002-02-08 EP EP02002815A patent/EP1233017B1/de not_active Expired - Lifetime
- 2002-02-08 US US10/071,662 patent/US6559142B2/en not_active Expired - Fee Related
- 2002-02-08 AT AT02002815T patent/ATE312829T1/de not_active IP Right Cessation
- 2002-02-08 BR BR0200414-3A patent/BR0200414A/pt not_active IP Right Cessation
- 2002-02-08 DE DE60207913T patent/DE60207913D1/de not_active Expired - Lifetime
- 2002-02-12 CA CA002371481A patent/CA2371481A1/en not_active Abandoned
- 2002-02-13 JP JP2002035628A patent/JP2002308859A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE312829T1 (de) | 2005-12-15 |
EP1233017A1 (de) | 2002-08-21 |
US20020169160A1 (en) | 2002-11-14 |
EP1233017B1 (de) | 2005-12-14 |
BR0200414A (pt) | 2003-04-29 |
JP2002308859A (ja) | 2002-10-23 |
US6559142B2 (en) | 2003-05-06 |
MXPA01013172A (es) | 2002-08-21 |
CA2371481A1 (en) | 2002-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA27567A1 (fr) | Perindopril | |
NO20040100L (no) | Nye forbindelser som anti-inflammasjons, immunmodulerende og anti-proliferative midler | |
ATE526319T1 (de) | Aktivator für den peroxisome proliferator- responsiven rezeptor delta | |
DK1485359T3 (da) | Natriumkanalblokkere | |
BR0207865A (pt) | Benzotiadiazinas inibidores de metaloproteinases de matriz | |
NO994482L (no) | Visse cykliske tiosubstituerte acylaminosyreamidderivater | |
ATE198739T1 (de) | 2,3-diaminopropionsäurederivate | |
ATE452889T1 (de) | Die hiv-protease inhibierende sulfonamide | |
KR960007592A (ko) | 신규한 피롤로카바졸 | |
DE60130766D1 (de) | Serotoninwiederaufnahme-inhibitoren | |
DE60207913D1 (de) | Als Matrix-Metalloproteinasehemmer verwendbare tricyclische Sulfonamide | |
ATE502005T1 (de) | Amphotere lipidverbindung und deren verwendung | |
ATE380172T1 (de) | Benzylaminanalogen | |
EA200400806A1 (ru) | Способ получения эхинокандиновых соединений | |
BRPI0416678A (pt) | pirazolpirimidinas | |
ATE291015T1 (de) | Alkylaminoderivate | |
EA200400666A3 (ru) | Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат | |
DK0819687T3 (da) | Benzothiophenforbindelser og anvendelser og formuleringer deraf | |
DE60221250D1 (de) | Bis(5-aryl-2-pyridyl)derivate | |
DK1312608T3 (da) | Discodermolid-analoge samt deres farmaceutiske anvendelse | |
TW200508211A (en) | 2-naphthylimino-1,3-thiazine derivatives | |
EA200200462A1 (ru) | Производные 2-арилхинолина, их получение и терапевтическое применение |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |