DE60206955T8 - Nervenreparaturgerät und verfahren zu seiner herstellung - Google Patents
Nervenreparaturgerät und verfahren zu seiner herstellung Download PDFInfo
- Publication number
- DE60206955T8 DE60206955T8 DE60206955T DE60206955T DE60206955T8 DE 60206955 T8 DE60206955 T8 DE 60206955T8 DE 60206955 T DE60206955 T DE 60206955T DE 60206955 T DE60206955 T DE 60206955T DE 60206955 T8 DE60206955 T8 DE 60206955T8
- Authority
- DE
- Germany
- Prior art keywords
- nerve repair
- production
- nerve
- repair device
- repair unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
- A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/32—Polylysine, polyornithine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Prostheses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0103827A SE0103827D0 (sv) | 2001-11-16 | 2001-11-16 | Nerve repair unit and method of producing it |
SE0103827 | 2001-11-16 | ||
PCT/SE2002/002058 WO2003041758A1 (en) | 2001-11-16 | 2002-11-12 | Nerve repair unit and method of producing it |
Publications (3)
Publication Number | Publication Date |
---|---|
DE60206955D1 DE60206955D1 (de) | 2005-12-01 |
DE60206955T2 DE60206955T2 (de) | 2006-07-27 |
DE60206955T8 true DE60206955T8 (de) | 2006-12-21 |
Family
ID=20286013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60206955T Active DE60206955T8 (de) | 2001-11-16 | 2002-11-12 | Nervenreparaturgerät und verfahren zu seiner herstellung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20050069525A1 (de) |
EP (1) | EP1443983B1 (de) |
AT (1) | ATE307623T1 (de) |
DE (1) | DE60206955T8 (de) |
DK (1) | DK1443983T3 (de) |
SE (1) | SE0103827D0 (de) |
WO (1) | WO2003041758A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007503221A (ja) * | 2003-08-22 | 2007-02-22 | テファ, インコーポレイテッド | ポリヒドロキシアルカノエート神経再生デバイス |
WO2005087287A1 (en) * | 2004-03-05 | 2005-09-22 | University Of Florida Research Foundation Inc. | Novel tissue engineered scaffolds derived from copper capillary alginate gels |
US8034777B2 (en) * | 2004-09-23 | 2011-10-11 | Receptopharm, Inc. | Modified anticholinergic neurotoxins as modulators of the autoimmune reaction |
BRPI0515973B8 (pt) | 2004-10-12 | 2021-07-27 | Fmc Biopolymer As | kit para produzir um gel de alginato, composição para preparar um gel e uso |
US20060239921A1 (en) * | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
US8185176B2 (en) | 2005-04-26 | 2012-05-22 | Novadaq Technologies, Inc. | Method and apparatus for vasculature visualization with applications in neurosurgery and neurology |
WO2007016790A1 (en) * | 2005-08-10 | 2007-02-15 | Novadaq Technologies, Inc. | Intra-operative head & neck nerve mapping |
US20070122344A1 (en) * | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
AU2008296975B2 (en) | 2007-08-28 | 2014-07-24 | Fmc Corporation | Delayed self-gelling alginate systems and uses thereof |
US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
EP3372250B1 (de) | 2008-05-02 | 2019-12-25 | Novadaq Technologies ULC | Verfahren zur herstellung und verwendung substanzbeladener erythrozyten zur beobachtung und behandlung von mikrovaskulärer hämodynamik |
US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
US8758374B2 (en) | 2010-09-15 | 2014-06-24 | University Of Utah Research Foundation | Method for connecting nerves via a side-to-side epineurial window using artificial conduits |
US9931121B2 (en) | 2011-10-17 | 2018-04-03 | University Of Utah Research Foundation | Methods and devices for connecting nerves |
US10842494B2 (en) | 2011-10-17 | 2020-11-24 | University Of Utah Research Foundation | Methods and devices for connecting nerves |
US10278585B2 (en) | 2012-06-21 | 2019-05-07 | Novadaq Technologies ULC | Quantification and analysis of angiography and perfusion |
WO2016049756A1 (en) | 2014-09-29 | 2016-04-07 | Novadaq Technologies Inc. | Imaging a target fluorophore in a biological material in the presence of autofluorescence |
KR101955134B1 (ko) | 2014-10-09 | 2019-03-06 | 노바다크 테크놀러지즈 유엘씨 | 형광-조정 광전용적맥파 측정기를 사용한 조직 내의 절대적인 혈류의 정량화 |
EP3419680A4 (de) * | 2016-02-25 | 2019-08-07 | University of Miami | Herstellung von schwann-zellen |
WO2017159700A1 (ja) * | 2016-03-14 | 2017-09-21 | 公益財団法人田附興風会 | 神経再生誘導材 |
WO2018010135A1 (zh) * | 2016-07-14 | 2018-01-18 | 中山大学附属第一医院 | 人体周围神经内部束型结构三维重建可视化集成方法 |
CA3049922A1 (en) | 2017-02-10 | 2018-08-16 | Novadaq Technologies ULC | Open-field handheld fluorescence imaging systems and methods |
US20200268931A1 (en) * | 2017-09-13 | 2020-08-27 | Tazuke Kofukai | Brain damage recovery material |
-
2001
- 2001-11-16 SE SE0103827A patent/SE0103827D0/xx unknown
-
2002
- 2002-11-12 AT AT02786318T patent/ATE307623T1/de not_active IP Right Cessation
- 2002-11-12 EP EP02786318A patent/EP1443983B1/de not_active Expired - Lifetime
- 2002-11-12 DK DK02786318T patent/DK1443983T3/da active
- 2002-11-12 WO PCT/SE2002/002058 patent/WO2003041758A1/en not_active Application Discontinuation
- 2002-11-12 US US10/494,371 patent/US20050069525A1/en not_active Abandoned
- 2002-11-12 DE DE60206955T patent/DE60206955T8/de active Active
Also Published As
Publication number | Publication date |
---|---|
WO2003041758A1 (en) | 2003-05-22 |
EP1443983B1 (de) | 2005-10-26 |
US20050069525A1 (en) | 2005-03-31 |
DE60206955D1 (de) | 2005-12-01 |
ATE307623T1 (de) | 2005-11-15 |
DE60206955T2 (de) | 2006-07-27 |
EP1443983A1 (de) | 2004-08-11 |
SE0103827D0 (sv) | 2001-11-16 |
DK1443983T3 (da) | 2006-03-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60206955T8 (de) | Nervenreparaturgerät und verfahren zu seiner herstellung | |
Kaigler et al. | Tissue engineering's impact on dentistry | |
DE69930257D1 (de) | Vorrichtung und verfahren zur herstellung eines implantierbaren gefässtransplantats | |
DE602004027188D1 (de) | Verfahren zur Herstellung bioabsorbierbarer, poröser und verstärkter Gewebeimplantate und dadurch hergestellte Implantate | |
RU2006145431A (ru) | Композиция для репарации хрящевой и костной ткани | |
NO20052949D0 (no) | Implantat inneholdende dyrkede bruksceller og fremgangsmate for fremstilling | |
DE69534869D1 (de) | Matrix für Gewebekultur, Verfahren zur Kultivierung von Gewebe, Verfahren zum Fixieren von kultiviertem Gewebe und fixierte Kunsthaut | |
BRPI0407221A (pt) | Extrato de geléia de wharton, método para a obtenção de uma célula progenitora humana, métodos para a produção de uma população de células, populações de células e método para a produção de tecido ósseo | |
BR0214217A (pt) | Aumento de função de órgão | |
EA200501562A1 (ru) | Медицинские имплантаты, содержащие биосовместимые покрытия | |
CA2441994A1 (en) | Composition and methods for the production of biological tissues and tissue constructs | |
BRPI0513773A8 (pt) | células tronco obtidas da polpa decídua ou de dentes permanentes e dos germes dentais, capazes de produzir tecido ósseo humano | |
PL1970068T3 (pl) | Naprawa tkanek z wykorzystaniem komórek multipotencjalnych | |
DE69431135D1 (de) | Methode zur Herstellung von Taxan-Typ Diterpen und Methode zur Gewinnung von Kulturzellen die Taxan-Typ Diterpen in hohen Ausbeuten herstellen | |
ATE334682T1 (de) | Verfahren zur herstellung von den trans-4-n- butylcyclohexanoicsaüre- und undecanoicsaüreestern von (7-alpha,11-beta)- dimethyl-17 beta -hydroxy-4-estren-3-one und deren medizynische anwendung | |
ATE535231T1 (de) | Verfahren zur herstellung von poly-iclc und seine verwendung | |
O'Sullivan et al. | Adhesion and integration of tissue engineered cartilage to porous polyethylene for composite ear reconstruction | |
ATE548414T1 (de) | Biokompatible polymere mit dreidimensionaler struktur und mit zellen, verfahren zu deren herstellung und seine verwendung in der medizin und in der chirurgie | |
CN110964637B (zh) | 一种体外动态细胞培养装置及其培养方法 | |
EA005322B1 (ru) | Способ и устройство для получения биологической ткани в камере роста | |
DK1405906T3 (da) | Schwann-celler stammende fra stromale knoglemarvsceller | |
ATE369122T1 (de) | Verfahren zur herstellung von implantaten mittels lösungsmittelfreier herstellung eines homogenisats | |
Mao | Calvarial development: cells and mechanics | |
WO2003074665A3 (en) | Microcapillary bioreactor for growth of biological tissue | |
DE69837212D1 (de) | Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |