DE602007001596D1 - Lipid-a-antagonisten mit anti-septischer-schock-wirkung, entzündungshemmender wirkung, antiischämischer wirkung und analgetischer wirkung - Google Patents

Lipid-a-antagonisten mit anti-septischer-schock-wirkung, entzündungshemmender wirkung, antiischämischer wirkung und analgetischer wirkung

Info

Publication number
DE602007001596D1
DE602007001596D1 DE602007001596T DE602007001596T DE602007001596D1 DE 602007001596 D1 DE602007001596 D1 DE 602007001596D1 DE 602007001596 T DE602007001596 T DE 602007001596T DE 602007001596 T DE602007001596 T DE 602007001596T DE 602007001596 D1 DE602007001596 D1 DE 602007001596D1
Authority
DE
Germany
Prior art keywords
effect
antagonists
lipid
septic shock
inflammatory activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007001596T
Other languages
English (en)
Inventor
Francesco Peri
Francesco Maria Nicotra
Barbara Simona Costa
Francesca Granucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universita degli Studi di Milano Bicocca
Original Assignee
Universita degli Studi di Milano Bicocca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universita degli Studi di Milano Bicocca filed Critical Universita degli Studi di Milano Bicocca
Publication of DE602007001596D1 publication Critical patent/DE602007001596D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE602007001596T 2006-03-22 2007-03-15 Lipid-a-antagonisten mit anti-septischer-schock-wirkung, entzündungshemmender wirkung, antiischämischer wirkung und analgetischer wirkung Active DE602007001596D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000530A ITMI20060530A1 (it) 2006-03-22 2006-03-22 Antinfiammatori a struttura monosaccaridica
PCT/EP2007/002279 WO2007107285A1 (en) 2006-03-22 2007-03-15 Lipid a antagonists with anti-septic shock, anti-inflammatory, anti-ischemia and analgesic activity

Publications (1)

Publication Number Publication Date
DE602007001596D1 true DE602007001596D1 (de) 2009-08-27

Family

ID=38106406

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007001596T Active DE602007001596D1 (de) 2006-03-22 2007-03-15 Lipid-a-antagonisten mit anti-septischer-schock-wirkung, entzündungshemmender wirkung, antiischämischer wirkung und analgetischer wirkung

Country Status (5)

Country Link
EP (1) EP1996603B1 (de)
DE (1) DE602007001596D1 (de)
ES (1) ES2331633T3 (de)
IT (1) ITMI20060530A1 (de)
WO (1) WO2007107285A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201001450A1 (ru) * 2008-04-09 2011-08-30 Зе Юнивёсэти Оф Ноф Кэрэлайн Эт Чэпл Хил Способы регулирования реаранжировки актинового цитоскелета и формирования межклеточных промежутков
EP2824157B1 (de) * 2012-03-08 2020-02-12 Kyushu University Neuartiges, aus zucker gewonnenes gelierungsmittel
IT201800000728A1 (it) * 2018-01-11 2019-07-11 Univ Degli Studi Di Milano Bicocca Nuovi antagonisti del tlr4 umano

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE457733T1 (de) * 2002-05-09 2010-03-15 Oncothyreon Inc Lipid-a- und andere kohlenhydrat-liganden-analoga

Also Published As

Publication number Publication date
EP1996603B1 (de) 2009-07-15
ITMI20060530A1 (it) 2007-09-23
ES2331633T3 (es) 2010-01-11
EP1996603A1 (de) 2008-12-03
WO2007107285A1 (en) 2007-09-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition