DE602005026667D1 - Pharmazeutische zusammensetzung zur behandlung von knochenfrakturen - Google Patents
Pharmazeutische zusammensetzung zur behandlung von knochenfrakturenInfo
- Publication number
- DE602005026667D1 DE602005026667D1 DE602005026667T DE602005026667T DE602005026667D1 DE 602005026667 D1 DE602005026667 D1 DE 602005026667D1 DE 602005026667 T DE602005026667 T DE 602005026667T DE 602005026667 T DE602005026667 T DE 602005026667T DE 602005026667 D1 DE602005026667 D1 DE 602005026667D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- bony
- composition
- bony callus
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000010392 Bone Fractures Diseases 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 210000003364 bony callus Anatomy 0.000 abstract 4
- VXGZBVMAPSWHLP-UHFFFAOYSA-N 4-[5-[4-(2-methyl-5-propan-2-yl-1,3-thiazol-4-yl)phenoxy]pentoxy]benzenecarboximidamide Chemical compound S1C(C)=NC(C=2C=CC(OCCCCCOC=3C=CC(=CC=3)C(N)=N)=CC=2)=C1C(C)C VXGZBVMAPSWHLP-UHFFFAOYSA-N 0.000 abstract 1
- 206010017076 Fracture Diseases 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 210000002808 connective tissue Anatomy 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000011164 ossification Effects 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20040052069 | 2004-07-05 | ||
| PCT/KR2005/002138 WO2006004369A1 (en) | 2004-07-05 | 2005-07-05 | Pharmaceutical composition for the treatment of bone fracture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005026667D1 true DE602005026667D1 (de) | 2011-04-14 |
Family
ID=35783131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005026667T Active DE602005026667D1 (de) | 2004-07-05 | 2005-07-05 | Pharmazeutische zusammensetzung zur behandlung von knochenfrakturen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7923443B2 (de) |
| EP (1) | EP1773332B1 (de) |
| JP (1) | JP4657296B2 (de) |
| KR (1) | KR100639041B1 (de) |
| CN (1) | CN101022800B (de) |
| AT (1) | ATE499938T1 (de) |
| AU (1) | AU2005260327B2 (de) |
| BR (1) | BRPI0513044A (de) |
| CA (1) | CA2572897C (de) |
| DE (1) | DE602005026667D1 (de) |
| ES (1) | ES2359721T3 (de) |
| HK (1) | HK1105585A1 (de) |
| IL (1) | IL180525A (de) |
| WO (1) | WO2006004369A1 (de) |
| ZA (1) | ZA200700115B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060017929A (ko) * | 2004-08-04 | 2006-02-28 | 동화약품공업주식회사 | 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물 |
| US7943646B2 (en) | 2006-01-31 | 2011-05-17 | Dong Wha Pharmaceutical Co., Ltd. | Benzamidine derivative, process for the preparation thereof and pharmaceutical composition comprising same |
| MX2009010339A (es) * | 2007-04-19 | 2009-10-16 | Dong Wha Pharm Co Ltd | Sal del acido 2-etanosulfonico de n-hidroxi-4{5-[4-(5-isopropil-2- metil-1,3-tiazol-4-il)fenoxi]pentoxi} benzamidina, procedimiento para su preparacion, y composicion farmaceutica que comprende la misma. |
| CA2732863A1 (en) * | 2008-08-01 | 2010-02-04 | Dong Wha Pharmaceutical Co., Ltd. | A pharmaceutical composition for preventing or treating osteoporosis comprising benzamidine derivatives or their salts, and alendronic acid or its salt |
| KR20100014090A (ko) * | 2008-08-01 | 2010-02-10 | 동화약품주식회사 | 벤즈아미딘 유도체 또는 이의 염, 및 비스포스포네이트를 포함하는 골다공증의 예방 또는 치료용 약학 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020037279A1 (en) * | 1996-09-13 | 2002-03-28 | Herman H. Vandenburgh | Delivery of bioactive compounds to an organism |
| KR100513302B1 (ko) * | 1997-02-04 | 2005-11-11 | 동화약품공업주식회사 | 3-아미노-1,2-벤조이소옥사졸 유도체, 이의 제조방법및 용도 |
| KR100454767B1 (ko) * | 2001-07-19 | 2004-11-03 | 동화약품공업주식회사 | 4-[(4-티아졸릴)페녹시]알콕시-벤즈아미딘 유도체의골다공증 예방 및 치료제로서의 용도 |
-
2005
- 2005-07-05 US US11/631,828 patent/US7923443B2/en not_active Expired - Fee Related
- 2005-07-05 WO PCT/KR2005/002138 patent/WO2006004369A1/en active Application Filing
- 2005-07-05 BR BRPI0513044-1A patent/BRPI0513044A/pt not_active IP Right Cessation
- 2005-07-05 DE DE602005026667T patent/DE602005026667D1/de active Active
- 2005-07-05 AU AU2005260327A patent/AU2005260327B2/en not_active Ceased
- 2005-07-05 EP EP05756781A patent/EP1773332B1/de not_active Not-in-force
- 2005-07-05 KR KR1020050060425A patent/KR100639041B1/ko not_active IP Right Cessation
- 2005-07-05 ES ES05756781T patent/ES2359721T3/es active Active
- 2005-07-05 CA CA2572897A patent/CA2572897C/en not_active Expired - Fee Related
- 2005-07-05 AT AT05756781T patent/ATE499938T1/de active
- 2005-07-05 CN CN2005800225540A patent/CN101022800B/zh not_active Expired - Fee Related
- 2005-07-05 JP JP2007519132A patent/JP4657296B2/ja not_active Expired - Fee Related
-
2007
- 2007-01-03 IL IL180525A patent/IL180525A/en not_active IP Right Cessation
- 2007-01-05 ZA ZA200700115A patent/ZA200700115B/en unknown
- 2007-10-10 HK HK07110938.7A patent/HK1105585A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006004369A1 (en) | 2006-01-12 |
| KR100639041B1 (ko) | 2006-10-27 |
| US20080287509A1 (en) | 2008-11-20 |
| ES2359721T3 (es) | 2011-05-26 |
| IL180525A0 (en) | 2008-03-20 |
| US7923443B2 (en) | 2011-04-12 |
| CN101022800B (zh) | 2010-05-05 |
| HK1105585A1 (en) | 2008-02-22 |
| KR20060049858A (ko) | 2006-05-19 |
| AU2005260327B2 (en) | 2009-10-01 |
| JP2008505068A (ja) | 2008-02-21 |
| CA2572897A1 (en) | 2006-01-12 |
| BRPI0513044A (pt) | 2008-04-22 |
| CN101022800A (zh) | 2007-08-22 |
| ATE499938T1 (de) | 2011-03-15 |
| ZA200700115B (en) | 2008-04-30 |
| EP1773332B1 (de) | 2011-03-02 |
| CA2572897C (en) | 2010-08-24 |
| AU2005260327A1 (en) | 2006-01-12 |
| EP1773332A4 (de) | 2008-03-12 |
| IL180525A (en) | 2011-10-31 |
| JP4657296B2 (ja) | 2011-03-23 |
| EP1773332A1 (de) | 2007-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004013971D1 (de) | Marknagel zur Behandlung von proximalen Oberschenkelknochenbrüchen | |
| CY1113286T1 (el) | Συνθεση με στροντιο και βιταμινη d για την προφυλαξη ή/καιθεραπευτικη αντιμετωπιση των παθησεων των χονδρων ή/και των οστων | |
| ATE499938T1 (de) | Pharmazeutische zusammensetzung zur behandlung von knochenfrakturen | |
| Ueng et al. | Management of large infected tibial defects with radical debridement and staged double-rib composite free transfer | |
| BR0211329A (pt) | Composição farmacêutica de derivados de 4-[(4-tiazolil)-fenoxi]alcoxi-benzamidina para tratamento de osteoporose | |
| EP0968729A3 (de) | Knochenregenerierungsmaterial | |
| Hsiao et al. | Exchange nailing for aseptic tibial shaft nonunion: emphasis on the influence of a concomitant fibulotomy | |
| WO2004019873A9 (en) | Methods of promoting osteogenesis | |
| Wu et al. | Tibial shaft malunion treated with reamed intramedullary nailing: a revised technique | |
| Bishop et al. | Provisional mini-fragment plate fixation in clavicle shaft fractures | |
| RU2405485C1 (ru) | Способ коррекции посттравматической вальгусной деформации заднего отдела стопы | |
| ATE450222T1 (de) | Osteosyntheseplatte zur operativen versorgung von knochenfrakturen | |
| Jo et al. | Results of Exchange Nailing in Hypertrophic Nonunion of Femoral Shaft Fracture Treated with Nailing | |
| Bari et al. | Infected gap non-union of lower tibia, fidelity by Ilizarov technique | |
| Rob et al. | Accordion maneuver with Ilizarov placed plate in situ, in a case of femoral shaft non-union and re-fracture with quiescent infection, discussion on treatment strategies: a case report | |
| RU1810050C (ru) | Способ лечени перелома шейки бедренной кости | |
| Hsu et al. | Indirect reduction with sliding compression screw stabilization for subtrochanteric fractures | |
| RU2392895C1 (ru) | Способ хирургического лечения привычного вывиха плеча | |
| Kim et al. | Minimally invasive percutaneous plate osteosynthesis using periarticular plate for distal tibial fractures | |
| Dickson et al. | The use of sulfathiazole in the treatment of subacute and chronic osteomyelitis: Frank D. Dickson MD (1882-1964), Rex L. Diveley MD, Richard Kiene MD. The 4th president of the AAOS 1935 (FDD). | |
| Arunpriya et al. | Treatment of condylar fractures: therapeutic controversies continue… | |
| Chand et al. | Managing difficult fractures due to Ballistic trauma with Ilizarov ring fixation | |
| Bramlage | Treatment of posttraumatic infections of bone | |
| Jeong et al. | The Effect of Sliding Inlay Bone Graft with Cancellous Chip Bone Graft in Non-Union or Delayed Union of the Tibia | |
| Potturi et al. | Effect of time lag on the treatment outcome of compound mandibular fractures |