DE602005026525D1 - Verfahren zur bestimmung eines gewebeabbauverfahrens durch nachweis von comp-neoepitopen - Google Patents
Verfahren zur bestimmung eines gewebeabbauverfahrens durch nachweis von comp-neoepitopenInfo
- Publication number
- DE602005026525D1 DE602005026525D1 DE602005026525T DE602005026525T DE602005026525D1 DE 602005026525 D1 DE602005026525 D1 DE 602005026525D1 DE 602005026525 T DE602005026525 T DE 602005026525T DE 602005026525 T DE602005026525 T DE 602005026525T DE 602005026525 D1 DE602005026525 D1 DE 602005026525D1
- Authority
- DE
- Germany
- Prior art keywords
- comp
- neoepitopes
- determining
- tissue removal
- removal procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000055007 Cartilage Oligomeric Matrix Human genes 0.000 abstract 8
- 101710176668 Cartilage oligomeric matrix protein Proteins 0.000 abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 108700005376 Cartilage Oligomeric Matrix Proteins 0.000 abstract 1
- 101000725508 Homo sapiens Cartilage oligomeric matrix protein Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 102000050578 human COMP Human genes 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 230000008354 tissue degradation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200400815 | 2004-05-24 | ||
| PCT/EP2005/005706 WO2005116658A2 (en) | 2004-05-24 | 2005-05-24 | Method for determining a tissue degradation process by detection of comp neoepitopes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005026525D1 true DE602005026525D1 (de) | 2011-04-07 |
Family
ID=34973791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005026525T Active DE602005026525D1 (de) | 2004-05-24 | 2005-05-24 | Verfahren zur bestimmung eines gewebeabbauverfahrens durch nachweis von comp-neoepitopen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080318337A1 (de) |
| EP (1) | EP1766411B1 (de) |
| AT (1) | ATE499614T1 (de) |
| DE (1) | DE602005026525D1 (de) |
| ES (1) | ES2360804T3 (de) |
| WO (1) | WO2005116658A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2236517A1 (de) * | 2009-03-31 | 2010-10-06 | Takara Bio, Inc. | Monoklonaler Anti-Fibronektinfragment-Antikörper |
| US20130084584A1 (en) * | 2010-03-31 | 2013-04-04 | Anna Blom | Method to detect tissue degradation leading to inflammation |
| EP2867679B1 (de) * | 2012-06-28 | 2018-07-18 | Nordic Bioscience A/S | Bestimmung des pathologischen knorpelumsatzes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4795702A (en) * | 1986-02-05 | 1989-01-03 | Immunogon Associates | Diagnostic method for gonorrhea by assay of IgA1 fragments |
| US5387504A (en) * | 1992-09-30 | 1995-02-07 | Merck & Co., Inc. | Monospecific antibodies and assay system for detecting stromelysin cleavage products |
| US5464820A (en) * | 1993-06-22 | 1995-11-07 | The University Hospital | Specific inhibitors of tissue kallikrein |
| US7300918B2 (en) * | 1994-01-14 | 2007-11-27 | Matthias Rath | Method of producing vaccines from protein signal oligopeptides |
| JP4189033B2 (ja) * | 1996-08-15 | 2008-12-03 | ノバルティス アクチエンゲゼルシャフト | 定量的関節炎状態のアッセイ |
| WO2001077384A2 (de) * | 2000-04-07 | 2001-10-18 | Epigenomics Ag | DETEKTION VON SNPs UND CYTOSIN-METHYLIERUNGEN |
-
2005
- 2005-05-24 AT AT05748087T patent/ATE499614T1/de not_active IP Right Cessation
- 2005-05-24 EP EP05748087A patent/EP1766411B1/de not_active Not-in-force
- 2005-05-24 DE DE602005026525T patent/DE602005026525D1/de active Active
- 2005-05-24 US US11/597,488 patent/US20080318337A1/en not_active Abandoned
- 2005-05-24 WO PCT/EP2005/005706 patent/WO2005116658A2/en active Application Filing
- 2005-05-24 ES ES05748087T patent/ES2360804T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1766411A2 (de) | 2007-03-28 |
| WO2005116658A2 (en) | 2005-12-08 |
| ES2360804T3 (es) | 2011-06-09 |
| EP1766411B1 (de) | 2011-02-23 |
| WO2005116658A3 (en) | 2006-05-26 |
| ATE499614T1 (de) | 2011-03-15 |
| US20080318337A1 (en) | 2008-12-25 |
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