DE602005022645D1 - Implantierbare vaskuläre Vorrichtung zur Abgabe von Topotecan in Kombination mit Rapamycin - Google Patents

Implantierbare vaskuläre Vorrichtung zur Abgabe von Topotecan in Kombination mit Rapamycin

Info

Publication number
DE602005022645D1
DE602005022645D1 DE602005022645T DE602005022645T DE602005022645D1 DE 602005022645 D1 DE602005022645 D1 DE 602005022645D1 DE 602005022645 T DE602005022645 T DE 602005022645T DE 602005022645 T DE602005022645 T DE 602005022645T DE 602005022645 D1 DE602005022645 D1 DE 602005022645D1
Authority
DE
Germany
Prior art keywords
devices
agents
compounds
medical device
utilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005022645T
Other languages
English (en)
Inventor
Robert Falotico
Tom Jay Parry
Jonathon Z Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cordis Corp
Original Assignee
Cordis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cordis Corp filed Critical Cordis Corp
Publication of DE602005022645D1 publication Critical patent/DE602005022645D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005022645T 2004-03-09 2005-03-08 Implantierbare vaskuläre Vorrichtung zur Abgabe von Topotecan in Kombination mit Rapamycin Active DE602005022645D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/796,397 US8828416B2 (en) 2004-03-09 2004-03-09 Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury

Publications (1)

Publication Number Publication Date
DE602005022645D1 true DE602005022645D1 (de) 2010-09-16

Family

ID=34827610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005022645T Active DE602005022645D1 (de) 2004-03-09 2005-03-08 Implantierbare vaskuläre Vorrichtung zur Abgabe von Topotecan in Kombination mit Rapamycin

Country Status (7)

Country Link
US (1) US8828416B2 (de)
EP (1) EP1574228B1 (de)
JP (1) JP5042458B2 (de)
CN (1) CN1679573B (de)
AT (1) ATE476205T1 (de)
CA (1) CA2499691C (de)
DE (1) DE602005022645D1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7611533B2 (en) 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US7419678B2 (en) * 2000-05-12 2008-09-02 Cordis Corporation Coated medical devices for the prevention and treatment of vascular disease
ATE526038T1 (de) 2003-03-28 2011-10-15 Innovational Holdings Llc Implantierbares medizinprodukt mit kontinuierlichem mittel-konzentrationsgefälle
US7244441B2 (en) * 2003-09-25 2007-07-17 Scios, Inc. Stents and intra-luminal prostheses containing map kinase inhibitors
US20050249776A1 (en) * 2003-12-19 2005-11-10 Chen Chao C Coated aneurysmal repair device
US8652502B2 (en) * 2003-12-19 2014-02-18 Cordis Corporation Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury
US8747881B2 (en) 2003-12-19 2014-06-10 Cordis Corporation Intraluminal medical devices in combination with therapeutic agents
DE102004024552B3 (de) * 2004-05-18 2005-12-08 Infineon Technologies Ag Speicherzellenanordnung mit einer Doppel-Speicherzelle
CA2575988C (en) 2004-08-04 2014-02-18 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
EP1933785B1 (de) * 2005-10-14 2015-04-22 Abbott Laboratories Zusammensetzungen, systeme, kits und verfahren zur verabreichung von rapamycin-analoga mit paclitaxel unter verwendung von medizinprodukten
WO2009085952A1 (en) 2007-12-20 2009-07-09 Brookwood Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
CN110075355A (zh) * 2013-10-22 2019-08-02 康斯瓦维有限责任公司 用于抑制支架型心瓣膜或生物假体的狭窄、阻塞或钙化的方法
CA2998170C (en) 2015-09-15 2023-10-03 Savage Medical, Inc. Devices and methods for anchoring a sheath in a tissue cavity

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US3959078A (en) 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
SU1088712A1 (ru) 1979-11-14 1984-04-30 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Аппарат дл циркул рного сшивани кровеносных сосудов
US4366819A (en) 1980-11-17 1983-01-04 Kaster Robert L Anastomotic fitting
US4368736A (en) 1980-11-17 1983-01-18 Kaster Robert L Anastomotic fitting
US4917091A (en) 1982-06-24 1990-04-17 Unilink Ab Annular fastening means
SE431609B (sv) 1982-06-24 1984-02-20 Unilink Ab Kirurgiskt instrument for astadkommande av anastomos och festelement herfor
US4722906A (en) 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
JPH0393520A (ja) 1989-09-07 1991-04-18 Tokan Kogyo Co Ltd 感温プラスチック成形体
JPH04559A (ja) 1990-04-17 1992-01-06 Toshiba Corp データ検索方式
US5234447A (en) 1990-08-28 1993-08-10 Robert L. Kaster Side-to-end vascular anastomotic staple apparatus
US5229172A (en) 1993-01-19 1993-07-20 Medtronic, Inc. Modification of polymeric surface by graft polymerization
US5350800A (en) 1993-01-19 1994-09-27 Medtronic, Inc. Method for improving the biocompatibility of solid surfaces
US5308641A (en) 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6120536A (en) 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5677286A (en) * 1995-04-27 1997-10-14 The University Of Michigan Glycosylated analogs of camptothecin
EP1226796B1 (de) 1997-02-03 2005-06-01 Angioguard, Inc. Gefässfilter
US20030129215A1 (en) 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US6890546B2 (en) * 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US6485514B1 (en) * 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US6425898B1 (en) 1998-03-13 2002-07-30 Cordis Corporation Delivery apparatus for a self-expanding stent
JP2002519335A (ja) * 1998-06-26 2002-07-02 クアナム メディカル コーポレイション 再狭窄の予防のためのトポイソメラーゼインヒビター
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6601233B1 (en) * 1999-07-30 2003-07-29 Accenture Llp Business components framework
US20070032853A1 (en) * 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
DE60135732D1 (de) * 2000-02-28 2008-10-23 Univ British Columbia Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
AU2001294869B2 (en) * 2000-09-29 2006-06-15 Cardinal Health 529, Llc Coated medical devices
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
GB0103668D0 (en) * 2001-02-15 2001-03-28 Biointeractions Ltd Methods and clinical devices for the inhibition or prevention of mammalian cell growth
DE10127011A1 (de) 2001-06-05 2002-12-12 Jomed Gmbh Implantate mit FK506
JP2003093520A (ja) * 2001-07-06 2003-04-02 Terumo Corp ステント
EP1273314A1 (de) 2001-07-06 2003-01-08 Terumo Kabushiki Kaisha Stent
WO2003020331A1 (de) 2001-09-03 2003-03-13 Oxigene, Inc. Implantate mit combretastatin a-4
US7195640B2 (en) * 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US7108701B2 (en) * 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
US20030065382A1 (en) * 2001-10-02 2003-04-03 Fischell Robert E. Means and method for the treatment of coronary artery obstructions
CN1568166A (zh) 2001-10-15 2005-01-19 荷姆泰克股份有限公司 预防再狭窄的涂层支架
US7318945B2 (en) 2003-07-09 2008-01-15 Medtronic Vascular, Inc. Laminated drug-polymer coated stent having dipped layers
US20050033417A1 (en) * 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent

Also Published As

Publication number Publication date
CA2499691C (en) 2010-06-15
CN1679573A (zh) 2005-10-12
EP1574228A2 (de) 2005-09-14
US20050202059A1 (en) 2005-09-15
CN1679573B (zh) 2010-09-29
EP1574228B1 (de) 2010-08-04
ATE476205T1 (de) 2010-08-15
CA2499691A1 (en) 2005-09-09
US8828416B2 (en) 2014-09-09
JP5042458B2 (ja) 2012-10-03
JP2005253972A (ja) 2005-09-22
EP1574228A3 (de) 2006-01-25

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