DE602005015241D1 - Hemmung des tumorwachstums und der metastasenbildung mit von atf2 stammenden peptiden - Google Patents

Hemmung des tumorwachstums und der metastasenbildung mit von atf2 stammenden peptiden

Info

Publication number
DE602005015241D1
DE602005015241D1 DE602005015241T DE602005015241T DE602005015241D1 DE 602005015241 D1 DE602005015241 D1 DE 602005015241D1 DE 602005015241 T DE602005015241 T DE 602005015241T DE 602005015241 T DE602005015241 T DE 602005015241T DE 602005015241 D1 DE602005015241 D1 DE 602005015241D1
Authority
DE
Germany
Prior art keywords
atf2
inhibition
therapies
metastasic
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005015241T
Other languages
English (en)
Inventor
Anindita Bhoumik
Ze Ev Ronai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icahn School of Medicine at Mount Sinai
Original Assignee
Mount Sinai School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai School of Medicine filed Critical Mount Sinai School of Medicine
Publication of DE602005015241D1 publication Critical patent/DE602005015241D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602005015241T 2004-10-18 2005-10-17 Hemmung des tumorwachstums und der metastasenbildung mit von atf2 stammenden peptiden Active DE602005015241D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62018404P 2004-10-18 2004-10-18
PCT/US2005/037634 WO2006044984A1 (en) 2004-10-18 2005-10-17 Inhibition of tumor growth and metastasis by atf2-derived peptides

Publications (1)

Publication Number Publication Date
DE602005015241D1 true DE602005015241D1 (de) 2009-08-13

Family

ID=35695674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005015241T Active DE602005015241D1 (de) 2004-10-18 2005-10-17 Hemmung des tumorwachstums und der metastasenbildung mit von atf2 stammenden peptiden

Country Status (6)

Country Link
US (1) US20090281025A1 (de)
EP (1) EP1809315B1 (de)
AT (1) ATE435025T1 (de)
CA (1) CA2595669A1 (de)
DE (1) DE602005015241D1 (de)
WO (1) WO2006044984A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007047093B4 (de) * 2007-10-01 2010-07-01 Ferton Holding S.A. Vorrichtung zur Messung von Fluoreszenzstrahlung an biologischen Substanzen mit einer Halbleitersensorenanordnung
US20110129844A1 (en) * 2007-12-21 2011-06-02 Ronai Ze Ev Use of Activating Transcription Factor-2 (ATF2) for Detecting Skin Cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650764A (en) * 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4797368A (en) * 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5034506A (en) * 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5139941A (en) * 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US4861719A (en) * 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4980289A (en) * 1987-04-27 1990-12-25 Wisconsin Alumni Research Foundation Promoter deficient retroviral vector
EP0623679B1 (de) * 1987-05-21 2003-06-25 Micromet AG Multifunktionelle Proteine mit vorbestimmter Zielsetzung
US5132405A (en) * 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5124263A (en) * 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) * 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5783682A (en) * 1990-07-27 1998-07-21 Isis Pharmaceuticals, Inc. Oligonucleotide mimics having nitrogen-containing linkages
US5792844A (en) * 1990-07-27 1998-08-11 Isis Pharmaceuticals, Inc. Oligonucleoside linkages containing adjacent nitrogen atoms
US5217889A (en) * 1990-10-19 1993-06-08 Roninson Igor B Methods and applications for efficient genetic suppressor elements
WO1997014709A1 (en) * 1995-10-13 1997-04-24 F. Hoffmann-La Roche Ag Antisense oligomers
US5677684A (en) * 1996-08-26 1997-10-14 Mcarthur; Evan B. Emergency vehicle sound-actuated traffic controller
US5814500A (en) * 1996-10-31 1998-09-29 The Johns Hopkins University School Of Medicine Delivery construct for antisense nucleic acids and methods of use
AU2002242214A1 (en) * 2001-02-15 2002-08-28 Mount Sinai School Of Medicine Of New York University Inhibition of atf2 activity to treat cancer

Also Published As

Publication number Publication date
WO2006044984A1 (en) 2006-04-27
CA2595669A1 (en) 2006-04-27
US20090281025A1 (en) 2009-11-12
EP1809315A1 (de) 2007-07-25
ATE435025T1 (de) 2009-07-15
EP1809315B1 (de) 2009-07-01

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Legal Events

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