DE602005012365D1 - Verfahren zur synthese von n-ä3-(3-cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n-ethylacetamid - Google Patents
Verfahren zur synthese von n-ä3-(3-cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n-ethylacetamidInfo
- Publication number
- DE602005012365D1 DE602005012365D1 DE602005012365T DE602005012365T DE602005012365D1 DE 602005012365 D1 DE602005012365 D1 DE 602005012365D1 DE 602005012365 T DE602005012365 T DE 602005012365T DE 602005012365 T DE602005012365 T DE 602005012365T DE 602005012365 D1 DE602005012365 D1 DE 602005012365D1
- Authority
- DE
- Germany
- Prior art keywords
- ethylacetamide
- phenylü
- synthesis
- propenyl
- dimethylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- FZSDJRKAWHMQFF-UHFFFAOYSA-N n-[3-[3-(dimethylamino)prop-2-enoyl]phenyl]-n-ethylacetamide;hydrochloride Chemical compound Cl.CCN(C(C)=O)C1=CC=CC(C(=O)C=CN(C)C)=C1 FZSDJRKAWHMQFF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0400325A HUP0400325A3 (en) | 2004-02-02 | 2004-02-02 | Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates |
| PCT/HU2005/000008 WO2005073235A2 (en) | 2004-02-02 | 2005-01-31 | Process for the synthesis of n- [3-(3-cyanopyrazolo [1,5a] pyrimidin-7-yl)-phenyl]-n-ethyl-acetamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005012365D1 true DE602005012365D1 (de) | 2009-03-05 |
Family
ID=89981959
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005012365T Expired - Fee Related DE602005012365D1 (de) | 2004-02-02 | 2005-01-31 | Verfahren zur synthese von n-ä3-(3-cyanopyrazoloä1,5aüpyrimidin-7-yl)-phenylü-n-ethylacetamid |
| DE602005015902T Expired - Fee Related DE602005015902D1 (de) | 2004-02-02 | 2005-01-31 | N-ä3- Ä3-(dimethylamino)-1-oxo-2-propenylÜphenylü-N-ethyl-acetamide hydrochlorid |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005015902T Expired - Fee Related DE602005015902D1 (de) | 2004-02-02 | 2005-01-31 | N-ä3- Ä3-(dimethylamino)-1-oxo-2-propenylÜphenylü-N-ethyl-acetamide hydrochlorid |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1950213B1 (de) |
| JP (1) | JP2007519700A (de) |
| AT (2) | ATE420882T1 (de) |
| DE (2) | DE602005012365D1 (de) |
| EA (1) | EA010830B1 (de) |
| HU (1) | HUP0400325A3 (de) |
| NO (1) | NO20063917L (de) |
| RS (1) | RS20060427A (de) |
| WO (1) | WO2005073235A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005099712A2 (en) * | 2004-04-19 | 2005-10-27 | Sanmar Speciality Chemicals Limited | Process for preparation of n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide |
| WO2006070244A2 (en) * | 2004-11-22 | 2006-07-06 | Bakulesh Mafatlal Khamar | A process for the preparation of zaleplon |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4626538A (en) | 1983-06-23 | 1986-12-02 | American Cyanamid Company | [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines |
| US5714607A (en) * | 1995-12-01 | 1998-02-03 | American Cyanamid Company | Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide |
| TR200402588T3 (tr) * | 2001-06-12 | 2004-11-22 | Biogal Gyogyszergyar Rt | N-[3-(3-siyanopirazolo[1,5-A]pirimidin-7-il)fenil]-N- etilasetamidin(zaleplon) üretim işlemi |
| WO2003011228A2 (en) * | 2001-08-01 | 2003-02-13 | Biogal Gyogyszergyar Rt | Purification and crystalline forms of zaleplon |
| PL207322B1 (pl) * | 2002-05-14 | 2010-11-30 | Adamed Społka Z Ograniczoną Odpowiedzialnością | Sposób wytwarzania zaleplonu |
-
2004
- 2004-02-02 HU HU0400325A patent/HUP0400325A3/hu unknown
-
2005
- 2005-01-31 DE DE602005012365T patent/DE602005012365D1/de not_active Expired - Fee Related
- 2005-01-31 EP EP08008434A patent/EP1950213B1/de active Active
- 2005-01-31 DE DE602005015902T patent/DE602005015902D1/de not_active Expired - Fee Related
- 2005-01-31 EP EP05708499A patent/EP1711501B1/de active Active
- 2005-01-31 JP JP2006550312A patent/JP2007519700A/ja active Pending
- 2005-01-31 EA EA200601417A patent/EA010830B1/ru not_active IP Right Cessation
- 2005-01-31 WO PCT/HU2005/000008 patent/WO2005073235A2/en active Application Filing
- 2005-01-31 AT AT05708499T patent/ATE420882T1/de not_active IP Right Cessation
- 2005-01-31 RS RSP-2006/0427A patent/RS20060427A/sr unknown
- 2005-01-31 AT AT08008434T patent/ATE438647T1/de not_active IP Right Cessation
-
2006
- 2006-09-01 NO NO20063917A patent/NO20063917L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HU0400325D0 (en) | 2004-04-28 |
| EP1711501B1 (de) | 2009-01-14 |
| EP1950213B1 (de) | 2009-08-05 |
| RS20060427A (en) | 2008-08-07 |
| JP2007519700A (ja) | 2007-07-19 |
| HUP0400325A2 (hu) | 2005-09-28 |
| EP1950213A2 (de) | 2008-07-30 |
| HUP0400325A3 (en) | 2005-11-28 |
| EP1711501A2 (de) | 2006-10-18 |
| EP1950213A3 (de) | 2008-08-13 |
| WO2005073235A2 (en) | 2005-08-11 |
| EA010830B1 (ru) | 2008-12-30 |
| NO20063917L (no) | 2006-11-01 |
| DE602005015902D1 (de) | 2009-09-17 |
| ATE420882T1 (de) | 2009-01-15 |
| EA200601417A1 (ru) | 2006-12-29 |
| WO2005073235A3 (en) | 2005-10-06 |
| ATE438647T1 (de) | 2009-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |