DE602004032262D1 - Verfahren zur kryogranulierung und lagerung von allergenen - Google Patents

Verfahren zur kryogranulierung und lagerung von allergenen

Info

Publication number
DE602004032262D1
DE602004032262D1 DE602004032262T DE602004032262T DE602004032262D1 DE 602004032262 D1 DE602004032262 D1 DE 602004032262D1 DE 602004032262 T DE602004032262 T DE 602004032262T DE 602004032262 T DE602004032262 T DE 602004032262T DE 602004032262 D1 DE602004032262 D1 DE 602004032262D1
Authority
DE
Germany
Prior art keywords
low temperature
temperature particles
relates
particles
storing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004032262T
Other languages
German (de)
English (en)
Inventor
Martin Richter-Friis
Signe Kolmos Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
ALK Abello AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALK Abello AS filed Critical ALK Abello AS
Priority claimed from PCT/DK2004/000878 external-priority patent/WO2005058474A1/en
Publication of DE602004032262D1 publication Critical patent/DE602004032262D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glanulating (AREA)
DE602004032262T 2003-12-19 2004-12-17 Verfahren zur kryogranulierung und lagerung von allergenen Active DE602004032262D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200301896 2003-12-19
US53167903P 2003-12-23 2003-12-23
PCT/DK2004/000878 WO2005058474A1 (en) 2003-12-19 2004-12-17 Cryogranulation and storage method for active pharmaceutical agents

Publications (1)

Publication Number Publication Date
DE602004032262D1 true DE602004032262D1 (de) 2011-05-26

Family

ID=34973435

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004032262T Active DE602004032262D1 (de) 2003-12-19 2004-12-17 Verfahren zur kryogranulierung und lagerung von allergenen

Country Status (6)

Country Link
JP (1) JP4755992B2 (ja)
CN (2) CN102657863A (ja)
AT (1) ATE505263T1 (ja)
DE (1) DE602004032262D1 (ja)
DK (1) DK1697033T3 (ja)
ES (1) ES2363342T3 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127173B (zh) * 2013-03-06 2015-01-21 苏州市红冠庄国药饮片有限公司 生产鹿血晶的雾化多层覆盖结晶工艺
CN114160040B (zh) * 2021-12-09 2022-07-12 广州风行乳业股份有限公司 一种液氮深冷制粒设备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5242846B2 (ja) * 1974-04-03 1977-10-27
WO2000006179A1 (en) * 1998-07-31 2000-02-10 Eli Lilly And Company Cryogranulation of activated protein c
DE60141680D1 (de) * 2000-01-14 2010-05-12 Univ Brown Res Found Verfahren zur herstellung von mikronisierte gefriergetrocknete partikeln
NZ525820A (en) * 2000-11-16 2005-01-28 Alk Abello As Mutant allergens
AUPR750501A0 (en) * 2001-09-05 2001-09-27 Gauci, Mark Products comprising quantum of bioparticles and method for production thereof

Also Published As

Publication number Publication date
JP2007514490A (ja) 2007-06-07
CN1894026B (zh) 2012-01-25
ATE505263T1 (de) 2011-04-15
ES2363342T3 (es) 2011-08-01
JP4755992B2 (ja) 2011-08-24
CN1894026A (zh) 2007-01-10
DK1697033T3 (da) 2011-06-27
CN102657863A (zh) 2012-09-12

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