DE602004028381D1 - Er of regulator of imprinted sites) moleküls - Google Patents
Er of regulator of imprinted sites) molekülsInfo
- Publication number
- DE602004028381D1 DE602004028381D1 DE602004028381T DE602004028381T DE602004028381D1 DE 602004028381 D1 DE602004028381 D1 DE 602004028381D1 DE 602004028381 T DE602004028381 T DE 602004028381T DE 602004028381 T DE602004028381 T DE 602004028381T DE 602004028381 D1 DE602004028381 D1 DE 602004028381D1
- Authority
- DE
- Germany
- Prior art keywords
- regulator
- boris
- moleküls
- imprinted sites
- nonfunctional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 102000035118 modified proteins Human genes 0.000 abstract 1
- 108091005573 modified proteins Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229940021747 therapeutic vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464484—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Inert Electrodes (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49751103P | 2003-08-25 | 2003-08-25 | |
PCT/US2004/027856 WO2005021029A2 (en) | 2003-08-25 | 2004-08-25 | Preventive cancer vaccine based on brother of regulator of imprinted sites molecule (boris) |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004028381D1 true DE602004028381D1 (en) | 2010-09-09 |
Family
ID=34272574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004028381T Active DE602004028381D1 (en) | 2003-08-25 | 2004-08-25 | Er of regulator of imprinted sites) moleküls |
Country Status (12)
Country | Link |
---|---|
US (2) | US7579452B2 (de) |
EP (1) | EP1667711B1 (de) |
JP (1) | JP2007504154A (de) |
CN (1) | CN1871025B (de) |
AT (1) | ATE475430T1 (de) |
AU (1) | AU2004268001B2 (de) |
CA (1) | CA2537161C (de) |
DE (1) | DE602004028381D1 (de) |
DK (1) | DK1667711T3 (de) |
IL (1) | IL173943A (de) |
RU (2) | RU2385163C2 (de) |
WO (1) | WO2005021029A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1802972B1 (de) | 2004-09-21 | 2009-05-27 | Government of the United States of America as represented by The Secretary of the Department of Health and Human Services | Auf immunreaktion gegen boris basierendes verfahren für den nachweis von krebs |
US20090081245A1 (en) * | 2007-09-07 | 2009-03-26 | Reznik Boris N | Assays for development of boris mutants suitable for vaccine development and small molecule inhibitors of wild-type boris |
CA2743904A1 (en) | 2008-11-17 | 2010-05-20 | The Regents Of The University Of Michigan | Cancer vaccine compositions and methods of using the same |
WO2015159118A2 (en) * | 2013-09-17 | 2015-10-22 | Obi Pharma, Inc. | Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment |
CA2962558C (en) * | 2014-09-24 | 2023-12-12 | Sapporo Medical University | A brother of the regulator of imprinted sites (boris)-derived tumor antigen peptide |
US11130798B2 (en) | 2015-05-19 | 2021-09-28 | La Jolla Institute For Allergy And Immunology | Human APOB100 epitopes, methods and uses for modulating inflammatory responses, and treating adverse cardiovascular events, disease and atherosclerosis |
KR20180050339A (ko) | 2015-09-04 | 2018-05-14 | 오비아이 파머 인코퍼레이티드 | 글리칸 어레이 및 사용 방법 |
US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
WO2017172990A1 (en) | 2016-03-29 | 2017-10-05 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
IL262296B1 (en) | 2016-04-22 | 2024-05-01 | Obi Pharma Inc | Cancer immunotherapy using immune activation or immune modulation by Globo-series antigens |
KR20230117482A (ko) | 2016-07-27 | 2023-08-08 | 오비아이 파머 인코퍼레이티드 | 면역원성/치료 글리칸 조성물 및 그의 용도 |
EP3491026A4 (de) | 2016-07-29 | 2020-07-29 | OBI Pharma, Inc. | Menschliche antikörper, pharmazeutische zusammensetzungen und verfahren |
AU2017361549B2 (en) | 2016-11-21 | 2023-12-21 | Obi Pharma, Inc. | Conjugated biological molecules, pharmaceutical compositions and methods |
KR102668476B1 (ko) * | 2017-12-13 | 2024-05-23 | 이노비오 파마수티컬즈, 인크. | Boris를 표적으로 하는 암 백신 및 이의 용도 |
US11203645B2 (en) | 2018-06-27 | 2021-12-21 | Obi Pharma, Inc. | Glycosynthase variants for glycoprotein engineering and methods of use |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5156841A (en) * | 1988-08-26 | 1992-10-20 | United States Of America | Anti-tumor vaccine |
UY24367A1 (es) * | 1995-11-23 | 2000-10-31 | Boehringer Ingelheim Int | Vacunas contra tumores y procedimiento para su produccion |
CN1326974A (zh) * | 2000-06-07 | 2001-12-19 | 上海博德基因开发有限公司 | 一种新的多肽——人转录阻抑蛋白ccctc-结合因子(ctcf)10.23和编码这种多肽的多核苷酸 |
AU2002249531A1 (en) * | 2001-04-02 | 2002-10-28 | Alimentary Health Limited | Immunotherapy based on dendritic cells |
US7375206B2 (en) * | 2002-02-22 | 2008-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | Brother of the regulator of imprinted sites (BORIS) |
-
2004
- 2004-08-25 DK DK04782353.9T patent/DK1667711T3/da active
- 2004-08-25 RU RU2006109359/13A patent/RU2385163C2/ru active
- 2004-08-25 WO PCT/US2004/027856 patent/WO2005021029A2/en active Application Filing
- 2004-08-25 JP JP2006524877A patent/JP2007504154A/ja active Pending
- 2004-08-25 AT AT04782353T patent/ATE475430T1/de active
- 2004-08-25 CA CA2537161A patent/CA2537161C/en not_active Expired - Fee Related
- 2004-08-25 CN CN2004800314130A patent/CN1871025B/zh not_active Expired - Fee Related
- 2004-08-25 EP EP04782353A patent/EP1667711B1/de not_active Not-in-force
- 2004-08-25 RU RU2010110441/10A patent/RU2556128C2/ru active
- 2004-08-25 DE DE602004028381T patent/DE602004028381D1/de active Active
- 2004-08-25 AU AU2004268001A patent/AU2004268001B2/en not_active Ceased
- 2004-08-25 US US10/569,907 patent/US7579452B2/en active Active
-
2006
- 2006-02-26 IL IL173943A patent/IL173943A/en active IP Right Grant
-
2009
- 2009-08-24 US US12/546,561 patent/US8114405B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1871025B (zh) | 2013-06-05 |
RU2010110441A (ru) | 2011-09-27 |
CA2537161A1 (en) | 2005-03-10 |
EP1667711A2 (de) | 2006-06-14 |
JP2007504154A (ja) | 2007-03-01 |
US20060286115A1 (en) | 2006-12-21 |
RU2556128C2 (ru) | 2015-07-10 |
US8114405B2 (en) | 2012-02-14 |
AU2004268001A1 (en) | 2005-03-10 |
IL173943A0 (en) | 2006-07-05 |
WO2005021029A2 (en) | 2005-03-10 |
ATE475430T1 (de) | 2010-08-15 |
CA2537161C (en) | 2014-07-29 |
WO2005021029A3 (en) | 2005-05-26 |
US7579452B2 (en) | 2009-08-25 |
RU2385163C2 (ru) | 2010-03-27 |
CN1871025A (zh) | 2006-11-29 |
IL173943A (en) | 2011-04-28 |
DK1667711T3 (da) | 2010-11-22 |
EP1667711B1 (de) | 2010-07-28 |
AU2004268001B2 (en) | 2010-04-22 |
RU2006109359A (ru) | 2007-10-10 |
US20100166790A1 (en) | 2010-07-01 |
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