DE602004015407D1 - Verfahren zur reduzierung des eisengehalts bei risedronat natrium - Google Patents
Verfahren zur reduzierung des eisengehalts bei risedronat natriumInfo
- Publication number
- DE602004015407D1 DE602004015407D1 DE602004015407T DE602004015407T DE602004015407D1 DE 602004015407 D1 DE602004015407 D1 DE 602004015407D1 DE 602004015407 T DE602004015407 T DE 602004015407T DE 602004015407 T DE602004015407 T DE 602004015407T DE 602004015407 D1 DE602004015407 D1 DE 602004015407D1
- Authority
- DE
- Germany
- Prior art keywords
- risedronate sodium
- iron content
- reducing iron
- iron
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title abstract 6
- IIDJRNMFWXDHID-UHFFFAOYSA-N Risedronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CC1=CC=CN=C1 IIDJRNMFWXDHID-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000759 risedronic acid Drugs 0.000 title abstract 4
- 229910052742 iron Inorganic materials 0.000 title abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacture Of Iron (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44106203P | 2003-01-17 | 2003-01-17 | |
| US44513903P | 2003-02-05 | 2003-02-05 | |
| PCT/US2004/001136 WO2004065397A1 (en) | 2003-01-17 | 2004-01-16 | Risedronate sodium having a very low content of iron |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004015407D1 true DE602004015407D1 (de) | 2008-09-11 |
Family
ID=32776044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004015407T Expired - Lifetime DE602004015407D1 (de) | 2003-01-17 | 2004-01-16 | Verfahren zur reduzierung des eisengehalts bei risedronat natrium |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7358360B2 (de) |
| EP (1) | EP1583768B1 (de) |
| JP (2) | JP3869456B2 (de) |
| AT (1) | ATE402942T1 (de) |
| CA (1) | CA2513543A1 (de) |
| DE (1) | DE602004015407D1 (de) |
| ES (1) | ES2311142T3 (de) |
| IL (1) | IL169569A (de) |
| PL (1) | PL377878A1 (de) |
| PT (1) | PT1583768E (de) |
| WO (1) | WO2004065397A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0300227A2 (hu) * | 2003-01-28 | 2004-09-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás nagy tisztaságú 2-szubsztituált -1-(hidroxi-etilidén)-1,1-biszfoszfonsavak és sóik előállítására |
| US20080286359A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| US7645460B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
| US7645459B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
| US20080287400A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| EP1888606A2 (de) * | 2005-05-28 | 2008-02-20 | PLIVA HRVATSKA d.o.o. | Verfahren und neues salz |
| JP5354858B2 (ja) * | 2006-05-09 | 2013-11-27 | 株式会社Ａｄｅｋａ | スルホンアミド化合物の金属塩を含有するポリエステル樹脂組成物 |
| MX2008014248A (es) | 2006-05-11 | 2009-02-23 | Ind Swift Lab Ltd | Proceso para la preparacion de sales y acido risedronico puros. |
| WO2009050731A2 (en) * | 2007-06-20 | 2009-04-23 | Alkem Laboratories Ltd | Novel process for preparing risedronic acid |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3623397A1 (de) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| SE9901272D0 (sv) * | 1999-04-09 | 1999-04-09 | Astra Ab | New improved formulation |
| US6677320B2 (en) * | 2000-01-20 | 2004-01-13 | Hoffmann-La Roches Inc. | Parenteral bisphosphonate composition with improved local tolerance |
| PE20011061A1 (es) * | 2000-02-01 | 2001-11-20 | Procter & Gamble | Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato |
| MXPA04010009A (es) * | 2002-04-11 | 2005-07-01 | Teva Pharma | Polimorfos y pseudopolimorfos de sodio de risedronato novedosos. |
| US7645460B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
-
2004
- 2004-01-16 CA CA002513543A patent/CA2513543A1/en not_active Abandoned
- 2004-01-16 US US10/759,919 patent/US7358360B2/en not_active Expired - Fee Related
- 2004-01-16 JP JP2005518469A patent/JP3869456B2/ja not_active Expired - Fee Related
- 2004-01-16 WO PCT/US2004/001136 patent/WO2004065397A1/en active Application Filing
- 2004-01-16 AT AT04702936T patent/ATE402942T1/de not_active IP Right Cessation
- 2004-01-16 ES ES04702936T patent/ES2311142T3/es not_active Expired - Lifetime
- 2004-01-16 DE DE602004015407T patent/DE602004015407D1/de not_active Expired - Lifetime
- 2004-01-16 PT PT04702936T patent/PT1583768E/pt unknown
- 2004-01-16 PL PL377878A patent/PL377878A1/pl not_active Application Discontinuation
- 2004-01-16 EP EP04702936A patent/EP1583768B1/de not_active Expired - Lifetime
-
2005
- 2005-07-07 IL IL169569A patent/IL169569A/en not_active IP Right Cessation
-
2006
- 2006-08-07 JP JP2006215059A patent/JP2007008956A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20040192655A1 (en) | 2004-09-30 |
| PT1583768E (pt) | 2008-09-11 |
| IL169569A (en) | 2010-04-29 |
| WO2004065397A1 (en) | 2004-08-05 |
| JP2006515867A (ja) | 2006-06-08 |
| JP2007008956A (ja) | 2007-01-18 |
| ATE402942T1 (de) | 2008-08-15 |
| US7358360B2 (en) | 2008-04-15 |
| JP3869456B2 (ja) | 2007-01-17 |
| EP1583768A1 (de) | 2005-10-12 |
| EP1583768B1 (de) | 2008-07-30 |
| PL377878A1 (pl) | 2006-02-20 |
| ES2311142T3 (es) | 2009-02-01 |
| CA2513543A1 (en) | 2004-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |