DE602004011385D1 - Substituierte arylcycloalkanolderivate und verfahren zur deren verwendung - Google Patents
Substituierte arylcycloalkanolderivate und verfahren zur deren verwendungInfo
- Publication number
- DE602004011385D1 DE602004011385D1 DE602004011385T DE602004011385T DE602004011385D1 DE 602004011385 D1 DE602004011385 D1 DE 602004011385D1 DE 602004011385 T DE602004011385 T DE 602004011385T DE 602004011385 T DE602004011385 T DE 602004011385T DE 602004011385 D1 DE602004011385 D1 DE 602004011385D1
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- Germany
- Prior art keywords
- derivatives
- combinations
- fibromyalgia
- vasomotor symptoms
- substituted
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
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- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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- Pyrrole Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US963111 | 1978-11-22 | ||
US51094303P | 2003-10-14 | 2003-10-14 | |
US510943P | 2003-10-14 | ||
US56130104P | 2004-04-12 | 2004-04-12 | |
US561301P | 2004-04-12 | ||
US56999604P | 2004-05-11 | 2004-05-11 | |
US569996P | 2004-05-11 | ||
US10/963,111 US7365076B2 (en) | 2003-10-14 | 2004-10-12 | Substituted aryl cycloalkanol derivatives and methods of their use |
PCT/US2004/033990 WO2005037809A1 (en) | 2003-10-14 | 2004-10-13 | Substituted aryl cycloalkanol derivatives and methods of their use |
Publications (2)
Publication Number | Publication Date |
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DE602004011385D1 true DE602004011385D1 (de) | 2008-03-06 |
DE602004011385T2 DE602004011385T2 (de) | 2009-05-14 |
Family
ID=34468487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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DE602004011385T Expired - Fee Related DE602004011385T2 (de) | 2003-10-14 | 2004-10-13 | Substituierte arylcycloalkanolderivate und verfahren zu deren verwendung |
Country Status (20)
Country | Link |
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US (2) | US7365076B2 (de) |
EP (1) | EP1687288B1 (de) |
JP (1) | JP2007509076A (de) |
KR (1) | KR20070026323A (de) |
AT (1) | ATE384055T1 (de) |
AU (1) | AU2004282193A1 (de) |
BR (1) | BRPI0415380A (de) |
CA (1) | CA2540207A1 (de) |
CR (1) | CR8313A (de) |
DE (1) | DE602004011385T2 (de) |
DK (1) | DK1687288T3 (de) |
EC (1) | ECSP066505A (de) |
ES (1) | ES2300841T3 (de) |
IL (1) | IL174539A0 (de) |
MX (1) | MXPA06003882A (de) |
NO (1) | NO20061383L (de) |
PE (1) | PE20050478A1 (de) |
PL (1) | PL1687288T3 (de) |
TW (1) | TW200526602A (de) |
WO (1) | WO2005037809A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7517899B2 (en) * | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7414052B2 (en) * | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
GB0513702D0 (en) | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
US20070129377A1 (en) * | 2005-12-05 | 2007-06-07 | Wyeth | Process for Preparing Substituted Aryl Cycloalkanol Derivatives |
US7612210B2 (en) | 2005-12-05 | 2009-11-03 | Wyeth | Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols |
US10407672B2 (en) * | 2006-03-27 | 2019-09-10 | Seattle Children's Hospital | Compositions and methods comprising the use of cell surface displayed homing endonucleases |
Family Cites Families (30)
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US3454554A (en) * | 1960-10-14 | 1969-07-08 | Colgate Palmolive Co | Aminoalkyliminodibenzyl compounds |
CS175831B1 (de) | 1974-12-17 | 1977-05-31 | ||
IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
US4310524A (en) * | 1980-04-11 | 1982-01-12 | Richardson-Merrell, Inc. | TCA Composition and method for rapid onset antidepressant therapy |
PH18686A (en) | 1981-05-26 | 1985-08-29 | Merck & Co Inc | 1-(3 halo-2-pyridinyl) piperazine |
US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
ZA864772B (en) | 1985-07-02 | 1987-02-25 | Merrell Dow Pharma | Novel chemical compounds |
ZA885824B (en) | 1987-08-14 | 1989-04-26 | Merrell Dow Pharma | Novel antidepressants |
US4826844A (en) | 1987-09-30 | 1989-05-02 | American Home Products Corporation | Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols |
AU652759B2 (en) | 1990-06-01 | 1994-09-08 | Aventisub Ii Inc. | (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)- 4-piperidinemethanol |
US5502047A (en) * | 1993-03-22 | 1996-03-26 | Kavey; Neil B. | Treatment for insomnia |
CN1146421C (zh) | 1996-03-25 | 2004-04-21 | 伊莱利利公司 | 治疗疼痛的组合物以及药物在制备所述组合物中的应用 |
PL342883A1 (en) | 1998-03-02 | 2001-07-16 | Lilly Co Eli | Fluoxetine hydrochloride for decreasing hot flashes |
DE60039132D1 (de) | 1999-04-06 | 2008-07-17 | Sepracor Inc | O-Desmethylvenlafaxin-Succinat |
ES2246485T3 (es) * | 1999-07-01 | 2006-02-16 | PHARMACIA & UPJOHN COMPANY LLC | (s,s)-reboxetina para tratar la incontinencia. |
HN2002000030A (es) | 2001-02-12 | 2004-06-07 | Wyeth Corp | Nueva sal succinato de o-desmetil-venlafaxina |
CA2442410A1 (en) | 2001-03-29 | 2002-10-10 | Owen Brendan Wallace | Duloxetine for treatment of hot flashes |
EP1266659A1 (de) | 2001-06-11 | 2002-12-18 | Pantarhei Bioscience B.V. | Pyridoxal im Verbindung mit Serotonine-hebenhemmer für die Behandlung des heissen Errötens |
US20040259850A1 (en) | 2001-10-31 | 2004-12-23 | Alves Stephen E. | Method for treating or preventing symptoms of hormonal variation including hot flashes |
US6602911B2 (en) | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
PT1485078E (pt) | 2002-03-15 | 2013-01-14 | Cypress Bioscience Inc | Milnacipran para o tratamento do síndrome do intestino irritável |
TW200402289A (en) * | 2002-05-17 | 2004-02-16 | Wyeth Corp | Methods of treating gastrointestinary and genitourinary pain disorders |
ITMI20021328A1 (it) | 2002-06-14 | 2003-12-15 | Recordati Ind Chimica E Farma | Nuove piperazine 1,4 - disostituite |
ITMI20021327A1 (it) | 2002-06-14 | 2003-12-15 | Recordati Chem Pharm | Nuove ossialchilpiperazine |
JP2005537307A (ja) | 2002-08-14 | 2005-12-08 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | のぼせの治療のためのレボキセチンの使用 |
US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
US20040180879A1 (en) | 2002-10-15 | 2004-09-16 | Deecher Darlene Coleman | Novel method of treating vasomotor symptoms |
US7345096B2 (en) * | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
JP2005336172A (ja) | 2004-04-26 | 2005-12-08 | Japan Tobacco Inc | 腎虚血再灌流障害治療又は予防薬 |
US20060122127A1 (en) | 2004-11-17 | 2006-06-08 | Cypress Bioscience, Inc. | Methods for reducing the side effects associated with mirtzapine treatment |
-
2004
- 2004-10-12 US US10/963,111 patent/US7365076B2/en not_active Expired - Fee Related
- 2004-10-13 WO PCT/US2004/033990 patent/WO2005037809A1/en active IP Right Grant
- 2004-10-13 TW TW093131003A patent/TW200526602A/zh unknown
- 2004-10-13 AT AT04795187T patent/ATE384055T1/de not_active IP Right Cessation
- 2004-10-13 EP EP04795187A patent/EP1687288B1/de active Active
- 2004-10-13 AU AU2004282193A patent/AU2004282193A1/en not_active Withdrawn
- 2004-10-13 JP JP2006535675A patent/JP2007509076A/ja not_active Withdrawn
- 2004-10-13 PL PL04795187T patent/PL1687288T3/pl unknown
- 2004-10-13 DE DE602004011385T patent/DE602004011385T2/de not_active Expired - Fee Related
- 2004-10-13 BR BRPI0415380-4A patent/BRPI0415380A/pt not_active IP Right Cessation
- 2004-10-13 CA CA002540207A patent/CA2540207A1/en not_active Abandoned
- 2004-10-13 DK DK04795187T patent/DK1687288T3/da active
- 2004-10-13 MX MXPA06003882A patent/MXPA06003882A/es active IP Right Grant
- 2004-10-13 KR KR1020067007287A patent/KR20070026323A/ko not_active Application Discontinuation
- 2004-10-13 ES ES04795187T patent/ES2300841T3/es active Active
- 2004-10-14 PE PE2004000996A patent/PE20050478A1/es not_active Application Discontinuation
-
2006
- 2006-03-23 IL IL174539A patent/IL174539A0/en unknown
- 2006-03-23 CR CR8313A patent/CR8313A/es unknown
- 2006-03-27 NO NO20061383A patent/NO20061383L/no not_active Application Discontinuation
- 2006-04-12 EC EC2006006505A patent/ECSP066505A/es unknown
-
2008
- 2008-02-14 US US12/031,187 patent/US7550456B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PL1687288T3 (pl) | 2008-06-30 |
DK1687288T3 (da) | 2008-07-07 |
MXPA06003882A (es) | 2006-07-03 |
JP2007509076A (ja) | 2007-04-12 |
EP1687288B1 (de) | 2008-01-16 |
TW200526602A (en) | 2005-08-16 |
US7550456B2 (en) | 2009-06-23 |
CA2540207A1 (en) | 2005-04-28 |
CR8313A (es) | 2006-10-04 |
ATE384055T1 (de) | 2008-02-15 |
US20080153826A1 (en) | 2008-06-26 |
WO2005037809A1 (en) | 2005-04-28 |
DE602004011385T2 (de) | 2009-05-14 |
IL174539A0 (en) | 2006-08-01 |
ECSP066505A (es) | 2006-10-10 |
AU2004282193A1 (en) | 2005-04-28 |
NO20061383L (no) | 2006-06-02 |
EP1687288A1 (de) | 2006-08-09 |
KR20070026323A (ko) | 2007-03-08 |
PE20050478A1 (es) | 2005-09-20 |
US20050143579A1 (en) | 2005-06-30 |
US7365076B2 (en) | 2008-04-29 |
BRPI0415380A (pt) | 2006-12-12 |
ES2300841T3 (es) | 2008-06-16 |
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